Does modulation of tau hyperphosphorylation represent a reasonable therapeutic strategy for Alzheimer’s disease? From preclinical studies to the clinical trials N Basheer, T Smolek, I Hassan, F Liu, K Iqbal, N Zilka, P Novak Molecular psychiatry 28 (6), 2197-2214, 2023 | 60 | 2023 |
Polo-like Kinase 1 as an emerging drug target: structure, function and therapeutic implications I Shakeel, N Basheer, GM Hasan, M Afzal, MI Hassan Journal of drug targeting 29 (2), 168-184, 2021 | 51 | 2021 |
Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase M Kunova Bosakova, A Nita, T Gregor, M Varecha, I Gudernova, B Fafilek, ... Proceedings of the National Academy of Sciences 116 (10), 4316-4325, 2019 | 43 | 2019 |
Monoclonal antibodies targeting two immunodominant epitopes on the Spike protein neutralize emerging SARS-CoV-2 variants of concern B Kovacech, L Fialova, P Filipcik, R Skrabana, M Zilkova, ... EBioMedicine 76, 2022 | 19 | 2022 |
Enriched environment ameliorates propagation of tau pathology and improves cognition in rat model of tauopathy V Mate, T Smolek, ZV Kazmerova, S Jadhav, V Brezovakova, B Jurkanin, ... Frontiers in Aging Neuroscience 14, 935973, 2022 | 6 | 2022 |
Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models N Basheer, L Buee, JP Brion, T Smolek, MK Muhammadi, J Hritz, ... Acta neuropathologica communications 12 (1), 52, 2024 | 1 | 2024 |
Disruption of extracellular matrix and perineuronal nets modulates extracellular space volume and geometry E Syková, I Voříšek, Z Starčuk, J Kratochvíla, I Pavlova, Y Ichikawa, ... Journal of Neuroscience 45 (8), 2025 | | 2025 |
TLR4-mediated chronic neuroinflammation has no effect on tangle pathology in a tauopathy mouse model N Basheer, MK Muhammadi, CL Freites, M Avila, MUD Momand, ... Frontiers in Aging Neuroscience 16, 1468602, 2024 | | 2024 |
AD-TAU INDUCED TANGLE-LIKE PATHOLOGY IN A NEWLY CHARACTERIZED TRANSGENIC MOUSE MODEL MK Muhammadi, T Smolek, I Uhrinova, N Basheer, N Zilka IBRO Neuroscience Reports 15, S283-S284, 2023 | | 2023 |
Second-Generation Antibodies Neutralize Emerging SARS-CoV-2 Variants of Concern B Kovacech, L Fialova, P Filipcik, R Skrabana, M Zilkova, ... bioRxiv, 2021.06. 09.447527, 2021 | | 2021 |