| Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-d-xylulose 5-phosphate precursor to isoprenoids … GA Sprenger, U Schörken, T Wiegert, S Grolle, AA De Graaf, SV Taylor, ... Proceedings of the National Academy of Sciences 94 (24), 12857-12862, 1997 | 654 | 1997 |
| Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing A Marx, AA de Graaf, W Wiechert, L Eggeling, H Sahm Biotechnology and bioengineering 49 (2), 111-129, 1996 | 456 | 1996 |
| A universal framework for 13C metabolic flux analysis W Wiechert, M Möllney, S Petersen, AA De Graaf Metabolic engineering 3 (3), 265-283, 2001 | 443 | 2001 |
| Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems W Wiechert, M Möllney, N Isermann, M Wurzel, AA de Graaf Biotechnology and bioengineering 66 (2), 69-85, 1999 | 370 | 1999 |
| Bidirectional reaction steps in metabolic networks: I. Modeling and simulation of carbon isotope labeling experiments W Wiechert, AA de Graaf Biotechnology and bioengineering 55 (1), 101-117, 1997 | 349 | 1997 |
| Quantitative Determination of Metabolic Fluxes during Coutilization of Two Carbon Sources: Comparative Analyses withCorynebacterium glutamicum during … VF Wendisch, AA de Graaf, H Sahm, BJ Eikmanns Journal of Bacteriology 182 (11), 3088-3096, 2000 | 345 | 2000 |
| Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis W Wiechert, C Siefke, AA de Graaf, A Marx Biotechnology and bioengineering 55 (1), 118-135, 1997 | 313 | 1997 |
| Beyond diversity: functional microbiomics of the human colon M Egert, AA De Graaf, H Smidt, WM De Vos, K Venema Trends in microbiology 14 (2), 86-91, 2006 | 282 | 2006 |
| Bidirectional reaction steps in metabolic networks: IV. Optimal design of isotopomer labeling experiments M Möllney, W Wiechert, D Kownatzki, AA de Graaf Biotechnology and bioengineering 66 (2), 86-103, 1999 | 251 | 1999 |
| Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria S Textor, VF Wendisch, AAD Graaf, U Müller, MI Linder, D Linder, ... Archives of microbiology 168, 428-436, 1997 | 242 | 1997 |
| In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum S Petersen, AA de Graaf, L Eggeling, M Mollney, W Wiechert, H Sahm Journal of Biological Chemistry 275 (46), 35932-35941, 2000 | 239 | 2000 |
| Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA‐based stable isotope probing P Kovatcheva‐Datchary, M Egert, A Maathuis, M Rajilić‐Stojanović, ... Environmental microbiology 11 (4), 914-926, 2009 | 215 | 2009 |
| Pathway analysis and metabolic engineering in Corynebacterium glutamicum H Sahm, L Eggeling, AA Graaf Walter de Gruyter 381 (9-10), 899-910, 2000 | 209 | 2000 |
| Kinetic properties of the glucose‐6‐phosphate and 6 phosphogluconate dehydrogenases from Corynebacterium glutamicum and their application for predicting pentose … B Moritz, K Striegel, AA de Graaf, H Sahm European Journal of Biochemistry 267 (12), 3442-3452, 2000 | 202 | 2000 |
| Analysis of carbon metabolism in Escherichia coli strains with an inactive phosphotransferase system by 13C labeling and NMR spectroscopy S Flores, G Gosset, N Flores, AA De Graaf, F Bolı́var Metabolic Engineering 4 (2), 124-137, 2002 | 184 | 2002 |
| Flux partitioning in the split pathway of lysine synthesis in Corynebacterium glutamicum Quantification by 13C‐ and 1H‐NMR spectroscopy K Sonntag, L Eggeling, AA De Graaf, H Sahm European journal of biochemistry 213 (3), 1325-1331, 1993 | 184 | 1993 |
| QUALITY: quantification improvement by converting lineshapes to the Lorentzian type AA De Graaf, JE Van Dijk, W BoéE Magnetic resonance in medicine 13 (3), 343-357, 1990 | 175 | 1990 |
| Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy MF Van Stee, AA de Graaf, AK Groen Cardiovascular diabetology 17, 1-22, 2018 | 162 | 2018 |
| Improved quantification of in vivo1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fitting AA De Graaf, W Bovee Magnetic Resonance in Medicine 15 (2), 305-319, 1990 | 158 | 1990 |
| Response of the central metabolism inCorynebacterium glutamicumto the use of an NADH-dependent glutamate dehydrogenase A Marx, BJ Eikmanns, H Sahm, AA de Graaf, L Eggeling Metabolic engineering 1 (1), 35-48, 1999 | 147 | 1999 |