| Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design J Lin, D Zhou, TA Steitz, YS Polikanov, MG Gagnon Annual Review of Biochemistry 87, 2018 | 343 | 2018 |
| The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin RN Roy, IB Lomakin, MG Gagnon, TA Steitz Nature Structural & Molecular Biology 22 (6), 466-469, 2015 | 199 | 2015 |
| Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition MG Gagnon, RN Roy, IB Lomakin, T Florin, AS Mankin, TA Steitz Nucleic acids research 44 (5), 2439-2450, 2016 | 186 | 2016 |
| Conformational changes of elongation factor G on the ribosome during tRNA translocation J Lin, MG Gagnon, D Bulkley, TA Steitz Cell 160 (1), 219-227, 2015 | 150 | 2015 |
| Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome MG Gagnon, SV Seetharaman, D Bulkley, TA Steitz Science 335 (6074), 1370-1372, 2012 | 135 | 2012 |
| Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome MG Gagnon, J Lin, D Bulkley, TA Steitz Science 345 (6197), 684-687, 2014 | 50 | 2014 |
| GU receptors of double helices mediate tRNA movement in the ribosome. MG Gagnon, SV Steinberg RNA 8 (7), 873-877, 2002 | 41 | 2002 |
| Structural basis for ribosome recycling by RRF and tRNA D Zhou, T Tanzawa, J Lin, MG Gagnon Nature Structural & Molecular Biology 27 (1), 25-32, 2020 | 38 | 2020 |
| Study of the functional interaction of the 900 tetraloop of 16S ribosomal RNA with helix 24 within the bacterial ribosome F Bélanger, MG Gagnon, SV Steinberg, PR Cunningham, ... Journal of molecular biology 338 (4), 683-693, 2004 | 29 | 2004 |
| Elongation factor 4 remodels the A-site tRNA on the ribosome MG Gagnon, J Lin, TA Steitz Proceedings of the National Academy of Sciences 113 (18), 4994-4999, 2016 | 24 | 2016 |
| Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation RS Basu, MB Sherman, MG Gagnon Nature communications 13 (1), 3388, 2022 | 18 | 2022 |
| The adenosine wedge: A new structural motif in ribosomal RNA MG Gagnon, SV Steinberg RNA 16 (2), 375-381, 2010 | 18 | 2010 |
| Mapping of the RNA recognition site of Escherichia coli ribosomal protein S7. F Robert, M Gagnon, D Sans, S Michnick, L Brakier-Gingras RNA 6 (11), 1649-1659, 2000 | 18 | 2000 |
| Close packing of helices 3 and 12 of 16 S rRNA is required for the normal ribosome function MG Gagnon, A Mukhopadhyay, SV Steinberg Journal of Biological Chemistry 281 (51), 39349-39357, 2006 | 15 | 2006 |
| A new family of bacterial ribosome hibernation factors K Helena-Bueno, MY Rybak, CL Ekemezie, R Sullivan, CR Brown, ... Nature 626 (8001), 1125-1132, 2024 | 14 | 2024 |
| Mechanisms of ribosome recycling in bacteria and mitochondria: a structural perspective SM Seely, MG Gagnon RNA biology 19 (1), 662-677, 2022 | 10 | 2022 |
| Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome SM Seely, NP Parajuli, A De Tarafder, X Ge, S Sanyal, MG Gagnon Nature Communications 14 (1), 4666, 2023 | 9 | 2023 |
| Antimicrobial peptides targeting bacterial ribosome IB Lomakin, MG Gagnon, TA Steitz Oncotarget 6 (22), 18744, 2015 | 8 | 2015 |
| Mechanistic insights into the alternative ribosome recycling by HflXr SM Seely, RS Basu, MG Gagnon Nucleic Acids Research 52 (7), 4053-4066, 2024 | 6 | 2024 |
| Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin MN Paranjpe, VI Marina, AA Grachev, TP Maviza, OA Tolicheva, ... Nucleic Acids Research 51 (1), 449-462, 2023 | 6 | 2023 |
Ivan LomakinAssociate Research Scientist, Yale UniversityVerified email at yale.edu