| VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression J Woolard, WY Wang, HS Bevan, Y Qiu, L Morbidelli, RO Pritchard-Jones, ... Cancer research 64 (21), 7822-7835, 2004 | 663 | 2004 |
| Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2 CJ Peach, VW Mignone, MA Arruda, DC Alcobia, SJ Hill, LE Kilpatrick, ... International journal of molecular sciences 19 (4), 1264, 2018 | 468 | 2018 |
| Expression of pro-and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors DG Nowak, J Woolard, EM Amin, O Konopatskaya, MA Saleem, ... Journal of cell science 121 (20), 3487-3495, 2008 | 435 | 2008 |
| Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis DG Nowak, EM Amin, ES Rennel, C Hoareau-Aveilla, M Gammons, ... Journal of Biological Chemistry 285 (8), 5532-5540, 2010 | 282 | 2010 |
| The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice ES Rennel, E Waine, H Guan, Y Schüler, W Leenders, J Woolard, ... British journal of cancer 98 (7), 1250-1257, 2008 | 179 | 2008 |
| Molecular diversity of VEGF-A as a regulator of its biological activity J Woolard, HS Bevan, SJ Harper, DO Bates Microcirculation 16 (7), 572-592, 2009 | 173 | 2009 |
| Role of the renin–angiotensin–aldosterone and kinin–kallikrein systems in the cardiovascular complications of COVID-19 and long COVID SL Cooper, E Boyle, SR Jefferson, CRA Heslop, P Mohan, GGJ Mohanraj, ... International Journal of Molecular Sciences 22 (15), 8255, 2021 | 73 | 2021 |
| Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization SJ Hill, LT May, B Kellam, J Woolard British journal of pharmacology 171 (5), 1102-1113, 2014 | 65 | 2014 |
| Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor … LE Kilpatrick, R Friedman-Ohana, DC Alcobia, K Riching, CJ Peach, ... Biochemical Pharmacology 136, 62-75, 2017 | 54 | 2017 |
| Use of a new proximity assay (NanoBRET) to investigate the ligand‐binding characteristics of three fluorescent ligands to the human β1‐adrenoceptor expressed … M Soave, LA Stoddart, A Brown, J Woolard, SJ Hill Pharmacology research & perspectives 4 (5), e00250, 2016 | 45 | 2016 |
| NanoBiT Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization M Soave, B Kellam, J Woolard, SJ Briddon, SJ Hill SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (2), 186-194, 2020 | 43 | 2020 |
| Real-time ligand binding of fluorescent VEGF-A isoforms that discriminate between VEGFR2 and NRP1 in living cells CJ Peach, LE Kilpatrick, R Friedman-Ohana, K Zimmerman, MB Robers, ... Cell chemical biology 25 (10), 1208-1218. e5, 2018 | 41 | 2018 |
| Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells LA Stoddart, ND Kindon, O Otun, CR Harwood, F Patera, DB Veprintsev, ... Communications biology 3 (1), 722, 2020 | 39 | 2020 |
| Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment CJ Hutchings, G Cseke, G Osborne, J Woolard, A Zhukov, M Koglin, ... MAbs 6 (1), 246-261, 2014 | 38 | 2014 |
| Complex formation between VEGFR2 and the β2-adrenoceptor LE Kilpatrick, DC Alcobia, CW White, CJ Peach, JR Glenn, K Zimmerman, ... Cell Chemical Biology 26 (6), 830-841. e9, 2019 | 37 | 2019 |
| Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms J Woolard, W Vousden, SJ Moss, A Krishnakumar, MVR Gammons, ... Chemical Science 2 (2), 273-278, 2011 | 34 | 2011 |
| A perspective on studying G-protein–coupled receptor signaling with resonance energy transfer biosensors in living organisms J van Unen, J Woolard, A Rinken, C Hoffmann, SJ Hill, J Goedhart, ... Molecular pharmacology 88 (3), 589-595, 2015 | 33 | 2015 |
| Visualizing ligand binding to a GPCR in vivo using NanoBRET DC Alcobia, AI Ziegler, A Kondrashov, E Comeo, S Mistry, B Kellam, ... Iscience 6, 280-288, 2018 | 31 | 2018 |
| Effects of 4 multitargeted receptor tyrosine kinase inhibitors on regional hemodynamics in conscious, freely moving rats JJ Carter, LV Fretwell, J Woolard The FASEB Journal 31 (3), 1193, 2016 | 27 | 2016 |
| Monitoring allosteric interactions with CXCR4 using NanoBiT conjugated nanobodies M Soave, R Heukers, B Kellam, J Woolard, MJ Smit, SJ Briddon, SJ Hill Cell Chemical Biology 27 (10), 1250-1261. e5, 2020 | 26 | 2020 |
