| New arylthioindoles: Potent Inhibitors of tubulin polymerization. 2. Structure− activity relationships and molecular modeling studies G De Martino, MC Edler, G La Regina, A Coluccia, MC Barbera, D Barrow, ... Journal of medicinal chemistry 49 (3), 947-954, 2006 | 448 | 2006 |
| Indole, a core nucleus for potent inhibitors of tubulin polymerization A Brancale, R Silvestri Medicinal research reviews 27 (2), 209-238, 2007 | 405 | 2007 |
| Arylthioindoles, potent inhibitors of tubulin polymerization G De Martino, G La Regina, A Coluccia, MC Edler, MC Barbera, ... Journal of medicinal chemistry 47 (25), 6120-6123, 2004 | 343 | 2004 |
| Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base C McGuigan, CJ Yarnold, G Jones, S Velázquez, H Barucki, A Brancale, ... Journal of medicinal chemistry 42 (22), 4479-4484, 1999 | 263 | 1999 |
| Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure− activity relationships and molecular modeling studies G La Regina, MC Edler, A Brancale, S Kandil, A Coluccia, F Piscitelli, ... Journal of medicinal chemistry 50 (12), 2865-2874, 2007 | 227 | 2007 |
| Synthesis and antitumor activity of 1, 5-disubstituted 1, 2, 4-triazoles as cis-restricted combretastatin analogues R Romagnoli, PG Baraldi, O Cruz-Lopez, C Lopez Cara, MD Carrion, ... Journal of medicinal chemistry 53 (10), 4248-4258, 2010 | 197 | 2010 |
| Synthesis and evaluation of 1, 5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity R Romagnoli, PG Baraldi, MK Salvador, D Preti, M Aghazadeh Tabrizi, ... Journal of medicinal chemistry 55 (1), 475-488, 2012 | 193 | 2012 |
| Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay A Narayanan, M Narwal, SA Majowicz, C Varricchio, SA Toner, ... Communications Biology 5 (1), 169, 2022 | 191 | 2022 |
| The tubulin colchicine domain: a molecular modeling perspective A Massarotti, A Coluccia, R Silvestri, G Sorba, A Brancale ChemMedChem 7 (1), 33-42, 2012 | 186 | 2012 |
| Synthesis and biological evaluation of 2-and 3-aminobenzo [b] thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, CL Cara, D Preti, F Fruttarolo, ... Journal of medicinal chemistry 50 (9), 2273-2277, 2007 | 186 | 2007 |
| Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer G Brahemi, FR Kona, A Fiasella, D Buac, J Soukupová, A Brancale, ... Journal of medicinal chemistry 53 (7), 2757-2765, 2010 | 181 | 2010 |
| Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide G La Regina, A Coluccia, A Brancale, F Piscitelli, V Gatti, G Maga, ... Journal of medicinal chemistry 54 (6), 1587-1598, 2011 | 170 | 2011 |
| Design, synthesis, and biological evaluation of thiophene analogues of chalcones R Romagnoli, PG Baraldi, MD Carrion, CL Cara, O Cruz-Lopez, D Preti, ... Bioorganic & medicinal chemistry 16 (10), 5367-5376, 2008 | 159 | 2008 |
| Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus C McGuigan, K Madela, M Aljarah, A Gilles, A Brancale, N Zonta, ... Bioorganic & medicinal chemistry letters 20 (16), 4850-4854, 2010 | 150 | 2010 |
| Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors G La Regina, R Bai, WM Rensen, E Di Cesare, A Coluccia, F Piscitelli, ... Journal of medicinal chemistry 56 (1), 123-149, 2013 | 141 | 2013 |
| Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus M Bassetto, T De Burghgraeve, L Delang, A Massarotti, A Coluccia, ... Antiviral research 98 (1), 12-18, 2013 | 125 | 2013 |
| Synthesis and biological evaluation of 1-methyl-2-(3′, 4′, 5′-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors R Romagnoli, PG Baraldi, T Sarkar, MD Carrion, CL Cara, O Cruz-Lopez, ... Journal of medicinal chemistry 51 (5), 1464-1468, 2008 | 121 | 2008 |
| The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition M Derudas, D Carta, A Brancale, C Vanpouille, A Lisco, L Margolis, ... Journal of medicinal chemistry 52 (17), 5520-5530, 2009 | 120 | 2009 |
| New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies G La Regina, T Sarkar, R Bai, MC Edler, R Saletti, A Coluccia, F Piscitelli, ... Journal of medicinal chemistry 52 (23), 7512-7527, 2009 | 117 | 2009 |
| Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents R Romagnoli, PG Baraldi, M Kimatrai Salvador, D Preti, ... Journal of medicinal chemistry 56 (6), 2606-2618, 2013 | 113 | 2013 |
