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David S. Leake
David S. Leake
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Cited by
Year
Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.
UP Steinbrecher, S Parthasarathy, DS Leake, JL Witztum, D Steinberg
Proceedings of the National Academy of Sciences 81 (12), 3883-3887, 1984
22861984
Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages
CV de Whalley, SM Rankin, JRS Hoult, W Jessup, DS Leake
Biochemical pharmacology 39 (11), 1743-1750, 1990
8681990
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal
T Ishii, K Itoh, E Ruiz, DS Leake, H Unoki, M Yamamoto, GE Mann
Circulation research 94 (5), 609-616, 2004
4952004
Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a …
CH MACPHEE, KE MOORES, HF BOYD, D DHANAK, RJ IFE, CA LEACH, ...
Biochemical Journal 338 (2), 479-487, 1999
4681999
α-tocopherol consumption during low-density-lipoprotein oxidation
W Jessup, SM Rankin, CV De Whalley, JRS Hoult, J Scott, DS Leake
Biochemical Journal 265 (2), 399-405, 1990
3741990
In vitro antioxidant activity of coffee compounds and their metabolites
JÁ Gómez-Ruiz, DS Leake, JM Ames
Journal of agricultural and food chemistry 55 (17), 6962-6969, 2007
3202007
The oxidative modification of low-density lipoproteins by macrophages
DS Leake, SM Rankin
Biochemical Journal 270 (3), 741-748, 1990
2401990
Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid
RA Patterson, ETM Horsley, DS Leake
Journal of Lipid Research 44 (3), 512-521, 2003
2392003
Effects of dairy products naturally enriched with cis-9, trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men
S Tricon, GC Burdge, EL Jones, JJ Russell, S El-Khazen, E Moretti, ...
The American journal of clinical nutrition 83 (4), 744-753, 2006
2132006
Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment?
CJJ Alderman, PR Bunyard, BM Chain, JC Foreman, DS Leake, DR Katz
Cardiovascular research 55 (4), 806-819, 2002
1762002
Inhibition of lipoprotein-associated phospholipase A2 diminishes the death-inducing effects of oxidised LDL on human monocyte-macrophages
KLH Carpenter, IF Dennis, IR Challis, DP Osborn, CH Macphee, ...
FEBS letters 505 (3), 357-363, 2001
1642001
Vitamin C protects human vascular smooth muscle cells against apoptosis induced by moderately oxidized LDL containing high levels of lipid hydroperoxides
RCM Siow, JP Richards, KC Pedley, DS Leake, GE Mann
Arteriosclerosis, thrombosis, and vascular biology 19 (10), 2387-2394, 1999
1571999
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2
AA Anwar, FYL Li, DS Leake, T Ishii, GE Mann, RCM Siow
Free Radical Biology and Medicine 39 (2), 227-236, 2005
1532005
Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions?
DS Leake
Atherosclerosis 129 (2), 149-157, 1997
1431997
Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses
EC Leigh-Firbank, AM Minihane, DS Leake, JW Wright, MC Murphy, ...
British Journal of Nutrition 87 (5), 435-445, 2002
1342002
Practical approaches to low density lipoprotein oxidation: whys, wherefores and pitfalls
C Rice-evans, D Leake, KR Bruckdorfer, AT Diplock
Free radical research 25 (4), 285-311, 1996
1331996
Acidic pH enables caeruloplasmin to catalyse the modification of low‐density lipoprotein
DJ Lamb, DS Leake
FEBS letters 338 (2), 122-126, 1994
1301994
Low density lipoprotein undergoes oxidation within lysosomes in cells
Y Wen, DS Leake
Circulation research 100 (9), 1337-1343, 2007
1202007
Transition metal ions within human atherosclerotic lesions can catalyse the oxidation of low density lipoprotein by macrophages
DJ Lamb, MJ Mitchinson, DS Leake
FEBS letters 374 (1), 12-16, 1995
1181995
Induction of the antioxidant stress proteins heme oxygenase‐1 and MSP23 by stress agents and oxidised LDL in cultured vascular smooth muscle cells
RCM Siow, T Ishii, H Sato, S Taketani, DS Leake, JH Sweiry, JD Pearson, ...
FEBS letters 368 (2), 239-242, 1995
1061995
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