Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. UP Steinbrecher, S Parthasarathy, DS Leake, JL Witztum, D Steinberg Proceedings of the National Academy of Sciences 81 (12), 3883-3887, 1984 | 2286 | 1984 |
Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages CV de Whalley, SM Rankin, JRS Hoult, W Jessup, DS Leake Biochemical pharmacology 39 (11), 1743-1750, 1990 | 868 | 1990 |
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal T Ishii, K Itoh, E Ruiz, DS Leake, H Unoki, M Yamamoto, GE Mann Circulation research 94 (5), 609-616, 2004 | 495 | 2004 |
Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a … CH MACPHEE, KE MOORES, HF BOYD, D DHANAK, RJ IFE, CA LEACH, ... Biochemical Journal 338 (2), 479-487, 1999 | 468 | 1999 |
α-tocopherol consumption during low-density-lipoprotein oxidation W Jessup, SM Rankin, CV De Whalley, JRS Hoult, J Scott, DS Leake Biochemical Journal 265 (2), 399-405, 1990 | 374 | 1990 |
In vitro antioxidant activity of coffee compounds and their metabolites JÁ Gómez-Ruiz, DS Leake, JM Ames Journal of agricultural and food chemistry 55 (17), 6962-6969, 2007 | 320 | 2007 |
The oxidative modification of low-density lipoproteins by macrophages DS Leake, SM Rankin Biochemical Journal 270 (3), 741-748, 1990 | 240 | 1990 |
Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid RA Patterson, ETM Horsley, DS Leake Journal of Lipid Research 44 (3), 512-521, 2003 | 239 | 2003 |
Effects of dairy products naturally enriched with cis-9, trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men S Tricon, GC Burdge, EL Jones, JJ Russell, S El-Khazen, E Moretti, ... The American journal of clinical nutrition 83 (4), 744-753, 2006 | 213 | 2006 |
Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment? CJJ Alderman, PR Bunyard, BM Chain, JC Foreman, DS Leake, DR Katz Cardiovascular research 55 (4), 806-819, 2002 | 176 | 2002 |
Inhibition of lipoprotein-associated phospholipase A2 diminishes the death-inducing effects of oxidised LDL on human monocyte-macrophages KLH Carpenter, IF Dennis, IR Challis, DP Osborn, CH Macphee, ... FEBS letters 505 (3), 357-363, 2001 | 164 | 2001 |
Vitamin C protects human vascular smooth muscle cells against apoptosis induced by moderately oxidized LDL containing high levels of lipid hydroperoxides RCM Siow, JP Richards, KC Pedley, DS Leake, GE Mann Arteriosclerosis, thrombosis, and vascular biology 19 (10), 2387-2394, 1999 | 157 | 1999 |
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2 AA Anwar, FYL Li, DS Leake, T Ishii, GE Mann, RCM Siow Free Radical Biology and Medicine 39 (2), 227-236, 2005 | 153 | 2005 |
Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions? DS Leake Atherosclerosis 129 (2), 149-157, 1997 | 143 | 1997 |
Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses EC Leigh-Firbank, AM Minihane, DS Leake, JW Wright, MC Murphy, ... British Journal of Nutrition 87 (5), 435-445, 2002 | 134 | 2002 |
Practical approaches to low density lipoprotein oxidation: whys, wherefores and pitfalls C Rice-evans, D Leake, KR Bruckdorfer, AT Diplock Free radical research 25 (4), 285-311, 1996 | 133 | 1996 |
Acidic pH enables caeruloplasmin to catalyse the modification of low‐density lipoprotein DJ Lamb, DS Leake FEBS letters 338 (2), 122-126, 1994 | 130 | 1994 |
Low density lipoprotein undergoes oxidation within lysosomes in cells Y Wen, DS Leake Circulation research 100 (9), 1337-1343, 2007 | 120 | 2007 |
Transition metal ions within human atherosclerotic lesions can catalyse the oxidation of low density lipoprotein by macrophages DJ Lamb, MJ Mitchinson, DS Leake FEBS letters 374 (1), 12-16, 1995 | 118 | 1995 |
Induction of the antioxidant stress proteins heme oxygenase‐1 and MSP23 by stress agents and oxidised LDL in cultured vascular smooth muscle cells RCM Siow, T Ishii, H Sato, S Taketani, DS Leake, JH Sweiry, JD Pearson, ... FEBS letters 368 (2), 239-242, 1995 | 106 | 1995 |