| The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients J Hallin, LD Engstrom, L Hargis, A Calinisan, R Aranda, DM Briere, ... Cancer discovery 10 (1), 54-71, 2020 | 1151 | 2020 |
| STAT3 signaling controls satellite cell expansion and skeletal muscle repair MT Tierney, T Aydogdu, D Sala, B Malecova, S Gatto, PL Puri, L Latella, ... Nature medicine 20 (10), 1182-1186, 2014 | 419 | 2014 |
| Denervation-activated STAT3–IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis L Madaro, M Passafaro, D Sala, U Etxaniz, F Lugarini, D Proietti, ... Nature cell biology 20 (8), 917-927, 2018 | 267 | 2018 |
| Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy B Malecova, S Gatto, U Etxaniz, M Passafaro, A Cortez, C Nicoletti, ... Nature communications 9 (1), 3670, 2018 | 189 | 2018 |
| Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease EC Lee, T Valencia, C Allerson, A Schairer, A Flaten, M Yheskel, ... Nature communications 10 (1), 4148, 2019 | 133 | 2019 |
| The KRASG12C Inhibitor MRTX849 Reconditions the Tumor Immune Microenvironment and Sensitizes Tumors to Checkpoint Inhibitor Therapy DM Briere, S Li, A Calinisan, N Sudhakar, R Aranda, L Hargis, DH Peng, ... Molecular cancer therapeutics 20 (6), 975-985, 2021 | 127 | 2021 |
| Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient H Heyn, E Vidal, S Sayols, JV Sanchez-Mut, S Moran, I Medina, ... Epigenetics 7 (6), 542-550, 2012 | 87 | 2012 |
| Transcription factor-directed re-wiring of chromatin architecture for somatic cell nuclear reprogramming toward trans-differentiation A Dall’Agnese, L Caputo, C Nicoletti, J di Iulio, A Schmitt, S Gatto, Y Diao, ... Molecular cell 76 (3), 453-472. e8, 2019 | 83 | 2019 |
| ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing S Gatto, M Gagliardi, M Franzese, S Leppert, M Papa, M Cammisa, ... Nucleic acids research 45 (10), 5739-5756, 2017 | 59 | 2017 |
| Comprehensive RNA-sequencing analysis in serum and muscle reveals novel small RNA signatures with biomarker potential for DMD AML Coenen-Stass, H Sork, S Gatto, C Godfrey, A Bhomra, K Krjutškov, ... Molecular Therapy-Nucleic Acids 13, 1-15, 2018 | 52 | 2018 |
| Genome-wide DNA methylation analysis identifies novel hypomethylated non-pericentromeric genes with potential clinical implications in ICF syndrome L Simo-Riudalbas, A Diaz-Lagares, S Gatto, M Gagliardi, AB Crujeiras, ... PloS one 10 (7), e0132517, 2015 | 41 | 2015 |
| Epigenetic alteration of microRNAs in DNMT3B-mutated patients of ICF syndrome S Gatto, F Della Ragione, A Cimmino, M Strazzullo, M Fabbri, M Mutarelli, ... Epigenetics 5 (5), 427-443, 2010 | 41 | 2010 |
| TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells B Malecova, A Dall'Agnese, L Madaro, S Gatto, P Coutinho Toto, S Albini, ... eLife, 2016 | 27 | 2016 |
| Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation H Cui, V Bansal, M Grunert, B Malecova, A Dall'Agnese, L Latella, S Gatto, ... PloS one 12 (6), e0179464, 2017 | 16 | 2017 |
| Variegated silencing through epigenetic modifications of a large Xq region in a case of balanced X; 2 translocation with Incontinentia Pigmenti-like phenotype R Genesio, D Melis, S Gatto, A Izzo, V Ronga, G Cappuccio, A Lanzo, ... Epigenetics 6 (10), 1242-1247, 2011 | 14 | 2011 |
| Abstract LB-C09: The KRASG12C inhibitor MRTX849 reconditions the tumor immune microenvironment and leads to durable complete responses in combination … DM Briere, A Calinisan, R Aranda, N Sudhakar, L Hargis, S Gatto, ... Molecular Cancer Therapeutics 18 (12_Supplement), LB-C09-LB-C09, 2019 | 11 | 2019 |
| The KRAS (G12C) inhibitor MRTX849 reconditions the tumor immune microenvironment and leads to durable complete responses in combination with anti-PD-1 therapy in a syngeneic … DM Briere, A Calinisan, R Aranda, N Sudhakar, L Hargis, S Gatto, ... MOLECULAR CANCER THERAPEUTICS 18 (12), 2019 | 8 | 2019 |
| Single Cell Gene Expression Profiling of Skeletal Muscle-Derived Cells S Gatto, PL Puri, B Malecova Muscle Stem Cells 1556, 191-219, 2017 | 8 | 2017 |
| CD6-ALCAM signaling regulates multiple effector/memory T cell functions J Ampudia, WW Young-Greenwald, J Badrani, S Gatto, A Pavlicek, ... The Journal of Immunology 204 (1_Supplement), 150.13-150.13, 2020 | 6 | 2020 |
| The Role of DNMT3B Mutations in the Pathogenesis of ICF Syndrome S Gatto, M D’Esposito, MR Matarazzo Patho-Epigenetics of Disease, 15-41, 2012 | 6 | 2012 |
Barbora MalecovaSanford Burnham Prebys Medical Discovery InstituteVerified email at sbpdiscovery.org