| Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015 | 2301 | 2015 |
| Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 2041 | 2012 |
| The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1486 | 2018 |
| Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ... Acta neuropathologica 123, 473-484, 2012 | 1178 | 2012 |
| Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015 | 1177 | 2015 |
| The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017 | 1072 | 2017 |
| Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 987 | 2012 |
| Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes JJ Molenaar, J Koster, DA Zwijnenburg, P Van Sluis, LJ Valentijn, ... Nature 483 (7391), 589-593, 2012 | 982 | 2012 |
| Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1), 59-71, 2012 | 979 | 2012 |
| RNA-Seq of tumor-educated platelets enables blood-based pan-cancer, multiclass, and molecular pathway cancer diagnostics MG Best, N Sol, I Kooi, J Tannous, BA Westerman, F Rustenburg, ... Cancer cell 28 (5), 666-676, 2015 | 910 | 2015 |
| New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 906 | 2016 |
| The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers J Muñoz, DE Stange, AG Schepers, M Van De Wetering, BK Koo, ... The EMBO journal 31 (14), 3079-3091, 2012 | 868 | 2012 |
| Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 853 | 2013 |
| Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features M Kool, J Koster, J Bunt, NE Hasselt, A Lakeman, P Van Sluis, D Troost, ... PloS one 3 (8), e3088, 2008 | 848 | 2008 |
| Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 839 | 2014 |
| Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 733 | 2014 |
| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 671 | 2014 |
| Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations TF Eleveld, DA Oldridge, V Bernard, J Koster, LC Daage, SJ Diskin, ... Nature genetics 47 (8), 864-871, 2015 | 590 | 2015 |
| Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ... Cancer cell 29 (3), 379-393, 2016 | 557 | 2016 |
| Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium DE Stange, BK Koo, M Huch, G Sibbel, O Basak, A Lyubimova, P Kujala, ... Cell 155 (2), 357-368, 2013 | 556 | 2013 |
Jan Molenaar-Verified email at prinsesmaximacentrum.nl