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Jay Horvat
Jay Horvat
university of newcastle
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Year
Immunological decision‐making: how does the immune system decide to mount a helper T‐cell response?
GE Kaiko, JC Horvat, KW Beagley, PM Hansbro
Immunology 123 (3), 326-338, 2008
8902008
Role for NLRP3 inflammasome–mediated, IL-1β–dependent responses in severe, steroid-resistant asthma
RY Kim, JW Pinkerton, AT Essilfie, AAB Robertson, KJ Baines, AC Brown, ...
American journal of respiratory and critical care medicine 196 (3), 283-297, 2017
4202017
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis
EL Beckett, RL Stevens, AG Jarnicki, RY Kim, I Hanish, NG Hansbro, ...
Journal of Allergy and Clinical Immunology 131 (3), 752-762. e7, 2013
2962013
Interferon-ε protects the female reproductive tract from viral and bacterial infection
KY Fung, NE Mangan, H Cumming, JC Horvat, JR Mayall, SA Stifter, ...
Science 339 (6123), 1088-1092, 2013
2742013
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2
RY Kim, JC Horvat, JW Pinkerton, MR Starkey, AT Essilfie, JR Mayall, ...
Journal of Allergy and Clinical Immunology 139 (2), 519-532, 2017
2192017
Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease
AT Essilfie, JL Simpson, JC Horvat, JA Preston, ML Dunkley, PS Foster, ...
PLoS pathogens 7 (10), e1002244, 2011
1972011
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
MC Runtsch, S Angiari, A Hooftman, R Wadhwa, Y Zhang, Y Zheng, ...
Cell metabolism 34 (3), 487-501. e8, 2022
1912022
Inflammasomes in the lung
JW Pinkerton, RY Kim, AAB Robertson, JA Hirota, LG Wood, DA Knight, ...
Molecular immunology 86, 44-55, 2017
1912017
Understanding the mechanisms of viral induced asthma: new therapeutic directions
NG Hansbro, JC Horvat, PA Wark, PM Hansbro
Pharmacology & therapeutics 117 (3), 313-353, 2008
1752008
Neonatal chlamydial infection induces mixed T-cell responses that drive allergic airway disease
JC Horvat, KW Beagley, MA Wade, JA Preston, NG Hansbro, DK Hickey, ...
American journal of respiratory and critical care medicine 176 (6), 556-564, 2007
1732007
Evidence for local and systemic immune activation in functional dyspepsia and the irritable bowel syndrome: a systematic review
G Burns, G Carroll, A Mathe, J Horvat, P Foster, MM Walker, NJ Talley, ...
Official journal of the American College of Gastroenterology| ACG 114 (3 …, 2019
1572019
Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma
AT Essilfie, JC Horvat, RY Kim, JR Mayall, JW Pinkerton, EL Beckett, ...
Thorax 70 (5), 458-467, 2015
1462015
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases
G Liu, MA Cooley, AG Jarnicki, ACY Hsu, PM Nair, TJ Haw, M Fricker, ...
JCI insight 1 (9), 2016
1452016
Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma
PM Hansbro, RY Kim, MR Starkey, C Donovan, K Dua, JR Mayall, G Liu, ...
Immunological reviews 278 (1), 41-62, 2017
1432017
Necroptosis signaling promotes inflammation, airway remodeling, and emphysema in chronic obstructive pulmonary disease
Z Lu, HP Van Eeckhoutte, G Liu, PM Nair, B Jones, CM Gillis, ...
American journal of respiratory and critical care medicine 204 (6), 667-681, 2021
1412021
Role of atypical bacterial infection of the lung in predisposition/protection of asthma
PM Hansbro, KW Beagley, JC Horvat, PG Gibson
Pharmacology & therapeutics 101 (3), 193-210, 2004
1412004
Inflammasomes in COPD and neutrophilic asthma
RY Kim, JW Pinkerton, PG Gibson, MA Cooper, JC Horvat, PM Hansbro
Thorax 70 (12), 1199-1201, 2015
1342015
Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology
JC Horvat, MR Starkey, RY Kim, S Phipps, PG Gibson, KW Beagley, ...
Journal of allergy and clinical immunology 125 (3), 617-625. e6, 2010
1322010
Saturated fatty acids, obesity, and the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome in asthmatic patients
LG Wood, Q Li, HA Scott, S Rutting, BS Berthon, PG Gibson, PM Hansbro, ...
Journal of Allergy and Clinical Immunology 143 (1), 305-315, 2019
1252019
Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin‐1c
G Liu, MA Cooley, PM Nair, C Donovan, AC Hsu, AG Jarnicki, TJ Haw, ...
The Journal of pathology 243 (4), 510-523, 2017
1202017
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