| Critical nodes in signalling pathways: insights into insulin action CM Taniguchi, B Emanuelli, CR Kahn Nature reviews Molecular cell biology 7 (2), 85-96, 2006 | 3609 | 2006 |
| New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure YH Tseng, E Kokkotou, TJ Schulz, TL Huang, JN Winnay, CM Taniguchi, ... Nature 454 (7207), 1000-1004, 2008 | 1323 | 2008 |
| Circulating nucleic acids are associated with outcomes of patients with pancreatic cancer V Bernard, DU Kim, FA San Lucas, J Castillo, K Allenson, FC Mulu, ... Gastroenterology 156 (1), 108-118. e4, 2019 | 361 | 2019 |
| Single-cell transcriptomics of pancreatic cancer precursors demonstrates epithelial and microenvironmental heterogeneity as an early event in neoplastic progression V Bernard, A Semaan, J Huang, FA San Lucas, FC Mulu, BM Stephens, ... Clinical Cancer Research 25 (7), 2194-2205, 2019 | 349 | 2019 |
| Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ CM Taniguchi, T Kondo, M Sajan, J Luo, R Bronson, T Asano, R Farese, ... Cell metabolism 3 (5), 343-353, 2006 | 343 | 2006 |
| Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin YH Tseng, AJ Butte, E Kokkotou, VK Yechoor, CM Taniguchi, ... Nature cell biology 7 (6), 601-611, 2005 | 279 | 2005 |
| Phosphoinositide 3-kinase regulatory subunit p85α suppresses insulin action via positive regulation of PTEN CM Taniguchi, TT Tran, T Kondo, J Luo, K Ueki, LC Cantley, CR Kahn Proceedings of the National Academy of Sciences 103 (32), 12093-12097, 2006 | 192 | 2006 |
| Suppression of PGC-1α is critical for reprogramming oxidative metabolism in renal cell carcinoma EL LaGory, C Wu, CM Taniguchi, CKC Ding, JT Chi, R von Eyben, ... Cell reports 12 (1), 116-127, 2015 | 189 | 2015 |
| Hypoxia inducible factor (HIF) in the tumor microenvironment: friend or foe? Y Huang, D Lin, CM Taniguchi Science China Life Sciences 60, 1114-1124, 2017 | 184 | 2017 |
| The phosphoinositide 3-kinase regulatory subunit p85α can exert tumor suppressor properties through negative regulation of growth factor signaling CM Taniguchi, J Winnay, T Kondo, RT Bronson, AR Guimaraes, ... Cancer research 70 (13), 5305-5315, 2010 | 175 | 2010 |
| Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes CM Taniguchi, EC Finger, AJ Krieg, C Wu, AN Diep, EL LaGory, K Wei, ... Nature medicine 19 (10), 1325-1330, 2013 | 171 | 2013 |
| Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer M Yu, ND Nguyen, Y Huang, D Lin, TN Fujimoto, JM Molkentine, ... Jci Insight 4 (16), e126915, 2019 | 154 | 2019 |
| PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2 CM Taniguchi, YR Miao, AN Diep, C Wu, EB Rankin, TF Atwood, L Xing, ... Science translational medicine 6 (236), 236ra64-236ra64, 2014 | 144 | 2014 |
| Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway KL Townsend, R Suzuki, TL Huang, E Jing, TJ Schulz, K Lee, ... The FASEB Journal 26 (5), 2187, 2012 | 131 | 2012 |
| A liver Hif-2α–Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition K Wei, SM Piecewicz, LM McGinnis, CM Taniguchi, SJ Wiegand, ... Nature medicine 19 (10), 1331-1337, 2013 | 123 | 2013 |
| Stromal HIF2 regulates immune suppression in the pancreatic cancer microenvironment CJG Garcia, Y Huang, NR Fuentes, MC Turner, ME Monberg, D Lin, ... Gastroenterology 162 (7), 2018-2031, 2022 | 108 | 2022 |
| The p85α Regulatory Subunit of Phosphoinositide 3-Kinase Potentiates c-Jun N-Terminal Kinase-Mediated Insulin Resistance CM Taniguchi, JO Aleman, K Ueki, J Luo, T Asano, H Kaneto, ... Molecular and cellular biology 27 (8), 2830-2840, 2007 | 108 | 2007 |
| ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer RCE Hsieh, S Krishnan, RC Wu, AR Boda, A Liu, M Winkler, WH Hsu, ... Science immunology 7 (72), eabl9330, 2022 | 99 | 2022 |
| A visually apparent and quantifiable CT imaging feature identifies biophysical subtypes of pancreatic ductal adenocarcinoma EJ Koay, Y Lee, V Cristini, JS Lowengrub, Y Kang, FAS Lucas, BP Hobbs, ... Clinical Cancer Research 24 (23), 5883-5894, 2018 | 97 | 2018 |
| Elucidation of tumor-stromal heterogeneity and the ligand-receptor interactome by single-cell transcriptomics in real-world pancreatic cancer biopsies JJ Lee, V Bernard, A Semaan, ME Monberg, J Huang, BM Stephens, ... Clinical Cancer Research 27 (21), 5912-5921, 2021 | 95 | 2021 |
Eugene KoayMD Anderson Cancer CenterVerified email at mdanderson.org