Structure-based design of prefusion-stabilized SARS-CoV-2 spikes CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ... Science 369 (6510), 1501-1505, 2020 | 1227 | 2020 |
Evolutionary optimization of fluorescent proteins for intracellular FRET AW Nguyen, PS Daugherty Nature biotechnology 23 (3), 355-360, 2005 | 817 | 2005 |
Intracellular protein interaction mapping with FRET hybrids X You, AW Nguyen, A Jabaiah, MA Sheff, KS Thorn, PS Daugherty Proceedings of the National Academy of Sciences 103 (49), 18458-18463, 2006 | 136 | 2006 |
The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes SM Costello, SR Shoemaker, HT Hobbs, AW Nguyen, CL Hsieh, ... Nature structural & molecular biology 29 (3), 229-238, 2022 | 116 | 2022 |
Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses RP Silva, Y Huang, AW Nguyen, CL Hsieh, OS Olaluwoye, TS Kaoud, ... Elife 12, 2023 | 75* | 2023 |
A cocktail of humanized anti–pertussis toxin antibodies limits disease in murine and baboon models of whooping cough AW Nguyen, EK Wagner, JR Laber, LL Goodfield, WE Smallridge, ... Science translational medicine 7 (316), 316ra195-316ra195, 2015 | 74 | 2015 |
SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines JE Bowen, YJ Park, C Stewart, JT Brown, WK Sharkey, AC Walls, A Joshi, ... Science Immunology 7 (78), eadf1421, 2022 | 57 | 2022 |
Expression and characterization of SARS-CoV-2 spike proteins JM Schaub, CW Chou, HC Kuo, K Javanmardi, CL Hsieh, J Goldsmith, ... Nature Protocols 16 (11), 5339-5356, 2021 | 51 | 2021 |
Neutralization of pertussis toxin by a single antibody prevents clinical pertussis in neonatal baboons AW Nguyen, AM DiVenere, JF Papin, S Connelly, M Kaleko, JA Maynard Science Advances 6 (6), eaay9258, 2020 | 43 | 2020 |
Human cytomegalovirus-specific T-cell receptor engineered for high affinity and soluble expression using mammalian cell display EK Wagner, AN Qerqez, CA Stevens, AW Nguyen, G Delidakis, ... Journal of Biological Chemistry 294 (15), 5790-5804, 2019 | 37 | 2019 |
Production of randomly mutated plasmid libraries using mutator strains AW Nguyen, PS Daugherty Directed Evolution Library Creation: Methods and Protocols, 39-44, 2003 | 35 | 2003 |
Construction of designed protein libraries using gene assembly mutagenesis PH Bessette, MA Mena, AW Nguyen, PS Daugherty Directed evolution library creation: Methods and protocols, 29-37, 2003 | 28 | 2003 |
Bioproduced proteins on demand (Bio-POD) in hydrogels using Pichia pastoris SF Yuan, SM Brooks, AW Nguyen, WL Lin, TG Johnston, JA Maynard, ... Bioactive Materials 6 (8), 2390-2399, 2021 | 22 | 2021 |
Identification of high affinity HER2 binding antibodies using CHO Fab surface display AW Nguyen, KC Le, JA Maynard Protein Engineering, Design and Selection 31 (3), 91-101, 2018 | 22 | 2018 |
Sample preparation for in situ nucleic acid analysis RA Fekete, A Nguyen US Patent 7,964,350, 2011 | 21 | 2011 |
Sample preparation for in situ nucleic acid analysis, methods and compositions therefor RA Fekete, A Nguyen US Patent 8,288,106, 2012 | 18 | 2012 |
Sample preparation for in situ nucleic acid analysis, methods and compositions therefor R Fekete, A Nguyen US Patent 8,828,664, 2014 | 12 | 2014 |
An antibody Fc engineered for conditional antibody-dependent cellular cytotoxicity at the low tumor microenvironment pH Y Liu, AG Lee, AW Nguyen, JA Maynard Journal of Biological Chemistry 298 (4), 2022 | 11 | 2022 |
Engineering antibodies for conditional activity in the solid tumor microenvironment Y Liu, AW Nguyen, JA Maynard Current Opinion in Biotechnology 78, 102809, 2022 | 8 | 2022 |
Humanized pertussis antibodies and uses thereof J Maynard, A Nguyen, E Padlan, E Wagner US Patent 9,512,204, 2016 | 8 | 2016 |