Diverse actions of ovarian steroids in the serotonin neural system CL Bethea, NZ Lu, C Gundlah, JM Streicher Frontiers in neuroendocrinology 23 (1), 41-100, 2002 | 633 | 2002 |
Development of functionally selective, small molecule agonists at kappa opioid receptors L Zhou, KM Lovell, KJ Frankowski, SR Slauson, AM Phillips, JM Streicher, ... Journal of Biological Chemistry 288 (51), 36703-36716, 2013 | 163 | 2013 |
MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart JM Streicher, S Ren, H Herschman, Y Wang Circulation research 106 (8), 1434-1443, 2010 | 136 | 2010 |
Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy O Drews, O Tsukamoto, D Liem, J Streicher, Y Wang, P Ping Circulation research 107 (9), 1094-1101, 2010 | 126 | 2010 |
Anxious behavior and fenfluramine-induced prolactin secretion in young rhesus macaques with different alleles of the serotonin reuptake transporter polymorphism (5HTTLPR) CL Bethea, JM Streicher, K Coleman, FKY Pau, R Moessner, JL Cameron Behavior Genetics 34, 295-307, 2004 | 120 | 2004 |
Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity JE LaVigne, R Hecksel, A Keresztes, JM Streicher Scientific reports 11 (1), 8232, 2021 | 110 | 2021 |
Functional selectivity of 6′-guanidinonaltrindole (6′-GNTI) at κ-opioid receptors in striatal neurons CL Schmid, JM Streicher, CE Groer, TA Munro, L Zhou, LM Bohn Journal of Biological Chemistry 288 (31), 22387-22398, 2013 | 99 | 2013 |
Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention JY Xie, M De Felice, CM Kopruszinski, N Eyde, J LaVigne, B Remeniuk, ... Cephalalgia 37 (8), 780-794, 2017 | 95 | 2017 |
Serotonin-related gene expression in female monkeys with individual sensitivity to stress CL Bethea, JM Streicher, SJ Mirkes, RL Sanchez, AP Reddy, JL Cameron Neuroscience 132 (1), 151-166, 2005 | 82 | 2005 |
Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt CL Schmid, JM Streicher, HY Meltzer, LM Bohn Neuropsychopharmacology 39 (8), 1902-1913, 2014 | 78 | 2014 |
Analgesic potential of terpenes derived from Cannabis sativa E Liktor-Busa, A Keresztes, J LaVigne, JM Streicher, TM Largent-Milnes, ... Pharmacological Reviews 73 (4), 1269-1297, 2021 | 75 | 2021 |
Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain MA Tarselli, KM Raehal, AK Brasher, JM Streicher, CE Groer, ... Nature chemistry 3 (6), 449-453, 2011 | 73 | 2011 |
The role of heat shock proteins in regulating receptor signal transduction JM Streicher Molecular Pharmacology 95 (5), 468-474, 2019 | 64 | 2019 |
Peripherally acting μ-opioid receptor antagonists for the treatment of opioid-related side effects: mechanism of action and clinical implications JM Streicher, EJ Bilsky Journal of pharmacy practice 31 (6), 658-669, 2018 | 63 | 2018 |
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N-and T … SS Bellampalli, Y Ji, A Moutal, S Cai, EMK Wijeratne, MA Gandini, J Yu, ... Pain 160 (1), 117-135, 2019 | 61 | 2019 |
TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth N Shah, S Kumar, N Zaman, CC Pan, JC Bloodworth, W Lei, JM Streicher, ... Nature communications 9 (1), 1696, 2018 | 59 | 2018 |
Discovery of small molecule kappa opioid receptor agonist and antagonist chemotypes through a HTS and hit refinement strategy KJ Frankowski, MP Hedrick, P Gosalia, K Li, S Shi, D Whipple, P Ghosh, ... ACS chemical neuroscience 3 (3), 221-236, 2012 | 59 | 2012 |
Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain W Lei, N Mullen, S McCarthy, C Brann, P Richard, J Cormier, K Edwards, ... Journal of Biological Chemistry 292 (25), 10414-10428, 2017 | 57 | 2017 |
Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids KM Olson, DI Duron, D Womer, R Fell, JM Streicher PloS one 14 (6), e0217371, 2019 | 53 | 2019 |
Strategies towards safer opioid analgesics—A review of old and upcoming targets BR Varga, JM Streicher, S Majumdar British journal of pharmacology 180 (7), 975-993, 2023 | 51 | 2023 |