Design and synthesis of minimalist terminal alkyne‐containing diazirine photo‐crosslinkers and their incorporation into kinase inhibitors for cell‐and tissue‐based proteome … Z Li, P Hao, L Li, CYJ Tan, X Cheng, GYJ Chen, SK Sze, HM Shen, ... Angewandte Chemie 125 (33), 8713-8718, 2013 | 388 | 2013 |
Tetrazole photoclick chemistry: reinvestigating its suitability as a bioorthogonal reaction and potential applications Z Li, L Qian, L Li, JC Bernhammer, HV Huynh, JS Lee, SQ Yao Angewandte Chemie International Edition 55 (6), 2002-2006, 2016 | 217 | 2016 |
Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2 X Luo, HB Gong, HY Gao, YP Wu, WY Sun, ZQ Li, G Wang, B Liu, L Liang, ... Cell Death & Differentiation 28 (6), 1971-1989, 2021 | 183 | 2021 |
“Minimalist” cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling Z Li, D Wang, L Li, S Pan, Z Na, CYJ Tan, SQ Yao Journal of the American Chemical Society 136 (28), 9990-9998, 2014 | 180 | 2014 |
2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells N Ma, J Hu, ZM Zhang, W Liu, M Huang, Y Fan, X Yin, J Wang, K Ding, ... Journal of the American Chemical Society 142 (13), 6051-6059, 2020 | 138 | 2020 |
Tetrazole‐based probes for integrated phenotypic screening, Affinity‐Based proteome profiling, and sensitive detection of a cancer biomarker K Cheng, JS Lee, P Hao, SQ Yao, K Ding, Z Li Angewandte Chemie 129 (47), 15240-15244, 2017 | 116 | 2017 |
Synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reactions Q Cai, Z Li, J Wei, L Fu, C Ha, D Pei, K Ding Organic letters 12 (7), 1500-1503, 2010 | 90 | 2010 |
Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents M Chen, X Lei, C Shi, M Huang, X Li, B Wu, Z Li, W Han, B Du, J Hu, ... The Journal of clinical investigation 127 (10), 3689-3701, 2017 | 84 | 2017 |
A Suite of “Minimalist” Photo‐Crosslinkers for Live‐Cell Imaging and Chemical Proteomics: Case Study with BRD4 Inhibitors S Pan, SY Jang, D Wang, SS Liew, Z Li, JS Lee, SQ Yao Angewandte Chemie International Edition 56 (39), 11816-11821, 2017 | 73 | 2017 |
Midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons J Sun, XM Lin, DH Lu, M Wang, K Li, SR Li, ZQ Li, CJ Zhu, ZM Zhang, ... The Journal of clinical investigation 133 (10), 2023 | 60 | 2023 |
4-Oxo-1, 4-dihydroquinoline-3-carboxamide derivatives as new Axl kinase inhibitors L Tan, Z Zhang, D Gao, J Luo, ZC Tu, Z Li, L Peng, X Ren, K Ding Journal of Medicinal Chemistry 59 (14), 6807-6825, 2016 | 59 | 2016 |
Assembly of indole-2-carboxylic acid esters through a ligand-free copper-catalysed cascade process Q Cai, Z Li, J Wei, C Ha, D Pei, K Ding Chemical communications, 7581-7583, 2009 | 57 | 2009 |
Developments of bioorthogonal handle-containing photo-crosslinkers for photoaffinity labeling H Guo, Z Li MedChemComm 8 (8), 1585-1591, 2017 | 47 | 2017 |
AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agents J Zhou, S Ng, Q Huang, YT Wu, Z Li, SQ Yao, HM Shen FEBS letters 587 (2), 170-177, 2013 | 42 | 2013 |
Multiplex Imaging and Cellular Target Identification of Kinase Inhibitors via an Affinity-Based Proteome Profiling Approach Y Su, S Pan, Z Li, L Li, X Wu, P Hao, SK Sze, SQ Yao Scientific reports 5 (1), 7724, 2015 | 40 | 2015 |
Cell‐and Tissue‐Based Proteome Profiling and Dual Imaging of Apoptosis Markers with Probes Derived from Venetoclax and Idasanutlin D Zhu, H Guo, Y Chang, Y Ni, L Li, ZM Zhang, P Hao, Y Xu, K Ding, Z Li Angewandte Chemie International Edition 57 (30), 9284-9289, 2018 | 38 | 2018 |
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth N Yao, CR Wang, MQ Liu, YJ Li, WM Chen, ZQ Li, Q Qi, JJ Lu, CL Fan, ... Signal Transduction and Targeted Therapy 5 (1), 214, 2020 | 37 | 2020 |
Competitive affinity-based proteome profiling and imaging to reveal potential cellular targets of betulinic acid H Guo, J Xu, P Hao, K Ding, Z Li Chemical Communications 53 (69), 9620-9623, 2017 | 37 | 2017 |
Applications of Activity‐Based Protein Profiling (ABPP) and Bioimaging in Drug Discovery J Xu, X Li, K Ding, Z Li Chemistry–An Asian Journal 15 (1), 34-41, 2020 | 32 | 2020 |
Development and application of novel electrophilic warheads in target identification and drug discovery Y Liu, S Lv, L Peng, C Xie, L Gao, H Sun, L Lin, K Ding, Z Li Biochemical Pharmacology 190, 114636, 2021 | 28 | 2021 |