CD24+ liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation TKW Lee, A Castilho, VCH Cheung, KH Tang, S Ma, IOL Ng Cell stem cell 9 (1), 50-63, 2011 | 690 | 2011 |
Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations S Ma, KW Chan, TKW Lee, KH Tang, JYH Wo, BJ Zheng, XY Guan Molecular Cancer Research 6 (7), 1146-1153, 2008 | 606 | 2008 |
miR-130b promotes CD133+ liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1 S Ma, KH Tang, YP Chan, TK Lee, PS Kwan, A Castilho, I Ng, K Man, ... Cell stem cell 7 (6), 694-707, 2010 | 456 | 2010 |
PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer B Diskin, S Adam, MF Cassini, G Sanchez, M Liria, B Aykut, C Buttar, E Li, ... Nature immunology 21 (4), 442-454, 2020 | 346 | 2020 |
CD133+ liver tumor‐initiating cells promote tumor angiogenesis, growth, and self‐renewal through neurotensin/interleukin‐8/CXCL1 signaling KH Tang, S Ma, TK Lee, YP Chan, PS Kwan, CM Tong, IO Ng, K Man, ... Hepatology 55 (3), 807-820, 2012 | 298 | 2012 |
SHP2 inhibition prevents adaptive resistance to MEK inhibitors in multiple cancer models C Fedele, H Ran, B Diskin, W Wei, J Jen, MJ Geer, K Araki, U Ozerdem, ... Cancer discovery 8 (10), 1237-1249, 2018 | 285 | 2018 |
SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling C Fedele, S Li, KW Teng, CJR Foster, D Peng, H Ran, P Mita, MJ Geer, ... Journal of Experimental Medicine 218 (1), e20201414, 2020 | 212 | 2020 |
Blockade of CD47‐mediated cathepsin S/protease‐activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma TKW Lee, VCH Cheung, P Lu, EYT Lau, S Ma, KH Tang, M Tong, J Lo, ... Hepatology 60 (1), 179-191, 2014 | 212 | 2014 |
A CD90+ Tumor-Initiating Cell Population with an Aggressive Signature and Metastatic Capacity in Esophageal Cancer KH Tang, YD Dai, M Tong, YP Chan, PS Kwan, L Fu, YR Qin, SW Tsao, ... Cancer research 73 (7), 2322-2332, 2013 | 180 | 2013 |
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients L Chen, THM Chan, YF Yuan, L Hu, J Huang, S Ma, J Wang, SS Dong, ... The Journal of clinical investigation 120 (4), 1178-1191, 2010 | 175 | 2010 |
Lupeol targets liver tumor‐initiating cells through phosphatase and tensin homolog modulation TKW Lee, A Castilho, VCH Cheung, KH Tang, S Ma, IOL Ng Hepatology 53 (1), 160-170, 2011 | 140 | 2011 |
Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma M Tong, KW Chan, JYJ Bao, KY Wong, JN Chen, PS Kwan, KH Tang, ... Cancer research 72 (22), 6024-6035, 2012 | 136 | 2012 |
MicroRNA-616 induces androgen-independent growth of prostate cancer cells by suppressing expression of tissue factor pathway inhibitor TFPI-2 S Ma, YP Chan, PS Kwan, TK Lee, M Yan, KH Tang, MT Ling, JR Vielkind, ... Cancer research 71 (2), 583-592, 2011 | 102 | 2011 |
Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21 A Hussain, V Voisin, S Poon, C Karamboulas, NHB Bui, J Meens, ... Journal of Experimental Medicine 217 (8), 2020 | 83 | 2020 |
Overriding adaptive resistance to sorafenib via combination therapy with SHP2 blockade in hepatocellular carcinoma CON Leung, M Tong, KPS Chung, L Zhou, N Che, KH Tang, J Ding, ... Hepatology, 2020 | 81* | 2020 |
Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer CA Chang, J Jen, S Jiang, A Sayad, AS Mer, KR Brown, AML Nixon, ... Cancer discovery 12 (4), 1022-1045, 2022 | 78 | 2022 |
Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC KH Tang, S Li, A Khodadadi-Jamayran, J Jen, H Han, K Guidry, T Chen, ... Cancer Discovery 12 (1), 47-61, 2021 | 78 | 2021 |
Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib H Han, S Li, T Chen, M Fitzgerald, S Liu, C Peng, KH Tang, S Cao, ... Cancer research 81 (20), 5311-5324, 2021 | 47 | 2021 |
N-Glycoproteomics of patient-derived xenografts: a strategy to discover tumor-associated proteins in high-grade serous ovarian cancer A Sinha, A Hussain, V Ignatchenko, A Ignatchenko, KH Tang, VWH Ho, ... Cell Systems 8 (4), 345-351. e4, 2019 | 33 | 2019 |
Prostate cancer cells modulate osteoblast mineralisation and osteoclast differentiation through Id-1 HF Yuen, YT Chiu, KK Chan, YP Chan, CW Chua, CM McCrudden, ... British journal of cancer 102 (2), 332-341, 2010 | 27 | 2010 |