Quantitative real-time imaging of glutathione X Jiang, J Chen, A Bajić, C Zhang, X Song, SL Carroll, ZL Cai, M Tang, ... Nature communications 8 (1), 16087, 2017 | 250 | 2017 |
Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis BL Woolbright, K Dorko, DJ Antoine, JI Clarke, P Gholami, F Li, SC Kumer, ... Toxicology and applied pharmacology 283 (3), 168-177, 2015 | 213 | 2015 |
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer NA Zhao, J Cao, L Xu, Q Tang, LE Dobrolecki, X Lv, M Talukdar, Y Lu, ... The Journal of clinical investigation 128 (4), 1283-1299, 2018 | 199 | 2018 |
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry WH Guo, X Qi, X Yu, Y Liu, CI Chung, F Bai, X Lin, D Lu, L Wang, J Chen, ... Nature communications 11 (1), 4268, 2020 | 168 | 2020 |
Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy F Li, J Lu, J Cheng, L Wang, T Matsubara, IL Csanaky, CD Klaassen, ... Nature medicine 19 (4), 418-420, 2013 | 167 | 2013 |
Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys H Peng, Q Wang, T Lou, J Qin, S Jung, V Shetty, F Li, Y Wang, X Feng, ... Nature communications 8 (1), 1493, 2017 | 162 | 2017 |
G‐protein‐coupled bile acid receptor plays a key role in bile acid metabolism and fasting‐induced hepatic steatosis in mice AC Donepudi, S Boehme, F Li, JYL Chiang Hepatology 65 (3), 813-827, 2017 | 142 | 2017 |
Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans MR McGill, F Li, MR Sharpe, CD Williams, SC Curry, X Ma, H Jaeschke Archives of toxicology 88, 391-401, 2014 | 142 | 2014 |
Hepatocyte‐specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice P Borude, G Edwards, C Walesky, F Li, X Ma, B Kong, GL Guo, U Apte Hepatology 56 (6), 2344-2352, 2012 | 115 | 2012 |
Macrophage miR-34a is a key regulator of cholesterol efflux and atherosclerosis Y Xu, Y Xu, Y Zhu, H Sun, C Juguilon, F Li, D Fan, L Yin, Y Zhang Molecular Therapy 28 (1), 202-216, 2020 | 108 | 2020 |
Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders [S] JM Ferrell, S Boehme, F Li, JYL Chiang Journal of lipid research 57 (7), 1144-1154, 2016 | 101 | 2016 |
Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice BL Woolbright, F Li, Y Xie, A Farhood, P Fickert, M Trauner, H Jaeschke Toxicology letters 228 (1), 56-66, 2014 | 93 | 2014 |
CYP2D plays a major role in berberine metabolism in liver of mice and humans Y Guo, F Li, X Ma, X Cheng, H Zhou, CD Klaassen Xenobiotica 41 (11), 996-1005, 2011 | 88 | 2011 |
An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis Y Wang, S Gunewardena, F Li, DJ Matye, C Chen, X Chao, T Jung, ... Nature Communications 11 (1), 3612, 2020 | 84 | 2020 |
Profiling the reactive metabolites of xenobiotics using metabolomic technologies F Li, J Lu, X Ma Chemical research in toxicology 24 (5), 744-751, 2011 | 76 | 2011 |
Role of bile acids in liver injury and regeneration following acetaminophen overdose B Bhushan, P Borude, G Edwards, C Walesky, J Cleveland, F Li, X Ma, ... The American journal of pathology 183 (5), 1518-1526, 2013 | 75 | 2013 |
CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid J Cheng, KW Krausz, F Li, X Ma, FJ Gonzalez Toxicology and applied pharmacology 266 (2), 245-253, 2013 | 65 | 2013 |
Serum metabolomic profiling identifies key metabolic signatures associated with pathogenesis of alcoholic liver disease in humans Z Yang, P Kusumanchi, RA Ross, L Heathers, K Chandler, A Oshodi, ... Hepatology Communications 3 (4), 542-557, 2019 | 63 | 2019 |
LC–MS-based metabolomics in profiling of drug metabolism and bioactivation F Li, FJ Gonzalez, X Ma Acta Pharmaceutica Sinica B 2 (2), 118-125, 2012 | 60 | 2012 |
Pharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD B York, F Li, F Lin, KL Marcelo, J Mao, A Dean, N Gonzales, D Gooden, ... Scientific reports 7 (1), 11793, 2017 | 59 | 2017 |