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Yazan Alwarawrah
Yazan Alwarawrah
Research Assistant Professor, University of North Carolina at Chapel Hill
Verified email at med.unc.edu
Title
Cited by
Cited by
Year
Changes in nutritional status impact immune cell metabolism and function
Y Alwarawrah, K Kiernan, NJ MacIver
Frontiers in immunology 9, 1055, 2018
5342018
Fasnall, a selective FASN inhibitor, shows potent anti-tumor activity in the MMTV-Neu model of HER2+ breast cancer
Y Alwarawrah, P Hughes, D Loiselle, DA Carlson, DB Darr, JL Jordan, ...
Cell chemical biology 23 (6), 678-688, 2016
1602016
Obesity-induced changes in T-cell metabolism are associated with impaired memory T-cell response to influenza and are not reversed with weight loss
J Rebeles, WD Green, Y Alwarawrah, AG Nichols, W Eisner, K Danzaki, ...
The Journal of Infectious Diseases 219 (10), 1652-1661, 2019
862019
Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70
MK Howe, K Bodoor, DA Carlson, PF Hughes, Y Alwarawrah, DR Loiselle, ...
Chemistry & biology 21 (12), 1648-1659, 2014
752014
Cellular fatty acid synthase is required for late stages of HIV-1 replication
MM Kulkarni, AN Ratcliff, M Bhat, Y Alwarawrah, P Hughes, J Arcos, ...
Retrovirology 14, 1-12, 2017
482017
Emerging mechanisms of obesity-associated immune dysfunction
SR Shaikh, MA Beck, Y Alwarawrah, NJ MacIver
Nature Reviews Endocrinology 20 (3), 136-148, 2024
422024
Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity
Y Alwarawrah, AG Nichols, WD Green, W Eisner, K Kiernan, J Warren, ...
International Journal of Obesity 44 (12), 2419-2429, 2020
382020
Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function
K Kiernan, Y Alwarawrah, AG Nichols, K Danzaki, NJ MacIver
Scientific reports 14 (1), 4331, 2024
112024
Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity
K Kiernan, AG Nichols, Y Alwarawrah, NJ MacIver
PLoS One 18 (6), e0286470, 2023
102023
Irgm1 regulates metabolism and function in T cell subsets
Y Alwarawrah, K Danzaki, AG Nichols, BE Fee, C Bock, G Kucera, ...
Scientific Reports 12 (1), 850, 2022
102022
Immune function in obesity
Y Alwarawrah, NJ MacIver
Pediatric obesity: etiology, pathogenesis and treatment, 363-378, 2018
52018
Inflammation and metabolism of influenza-stimulated peripheral blood mononuclear cells from adults with obesity following bariatric surgery
WD Green, Y Alwarawrah, AE Al-Shaer, Q Shi, M Armstrong, J Manke, ...
The Journal of Infectious Diseases 227 (1), 92-102, 2023
42023
Overcoming lapatinib resistance by the fatty acid synthase inhibitor HS-106
Y Alwarawrah, P Hughes, R Safi, DP McDonnell, NL Spector, ...
Cancer Research 75 (15_Supplement), 2703-2703, 2015
42015
Type I interferon signaling and peroxisomal dysfunction contribute to enhanced inflammatory cytokine production in IRGM1-deficient macrophages
BE Fee, LR Fee, M Menechella, B Affeldt, AR Sprouse, A Bounini, ...
Journal of Biological Chemistry 300 (11), 107883, 2024
12024
Fatty acid synthase inhibitors
J Kwiek, T Haystead, P Hughes, Y Alwarawrah
US Patent 10,966,981, 2021
12021
Fatty acid synthase inhibitors
J KWIEK, T Haystead, P Hughes, Y ALWARAWRAH
12017
Alveolar and Bone Marrow-derived Macrophages Differ in Metabolism and Glutamine Utilization
CL Vigeland, JD Link, HS Beggs, Y Alwarawrah, BM Ehrmann, H Dang, ...
American Journal of Respiratory Cell and Molecular Biology, 2024
2024
Glutamine-mediated Changes in the Activity of Alveolar and Bone Marrow-derived Macrophages
CL Vigeland, JD Link, Y Alwarawrah, CM Doerschuk
A31. IMMUNE CELL MOLECULAR ACTIVATION SWITCH IN LUNG INJURY AND INFLAMMATION …, 2024
2024
Metformin treatment of CD8 T cells decreases pro-inflammatory cytokine production and shifts their metabolic state toward oxidative metabolism
CT Molloy, Y Alwarawrah, N MacIver
The Journal of Immunology 210 (1_Supplement), 66.12-66.12, 2023
2023
OR12-2 Obesity Induces Changes in T Cell Metabolism and Function
Y Alwarawrah, A Nichols, W Eisner, N MacIver
Journal of the Endocrine Society 3 (Supplement_1), OR12-2, 2019
2019
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Articles 1–20