| Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle DW Frederick, E Loro, L Liu, A Davila, K Chellappa, IM Silverman, ... Cell metabolism 24 (2), 269-282, 2016 | 378 | 2016 |
| Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease R Nativio, G Donahue, A Berson, Y Lan, A Amlie-Wolf, F Tuzer, JB Toledo, ... Nature neuroscience 21 (4), 497-505, 2018 | 334 | 2018 |
| 2014 PS Anderson CreateSpace, 2013 | 248 | 2013 |
| N6-methyladenosine inhibits local ribonucleolytic cleavage to stabilize mRNAs in Arabidopsis SJ Anderson, MC Kramer, SJ Gosai, X Yu, LE Vandivier, ADL Nelson, ... Cell reports 25 (5), 1146-1157. e3, 2018 | 221 | 2018 |
| Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z SJ Gosai, JH Kwak, CJ Luke, OS Long, DE King, KJ Kovatch, ... PloS one 5 (11), e15460, 2010 | 216 | 2010 |
| Global analysis of ribosome-associated noncoding RNAs unveils new modes of translational regulation J Bazin, K Baerenfaller, SJ Gosai, BD Gregory, M Crespi, J Bailey-Serres Proceedings of the National Academy of Sciences 114 (46), E10018-E10027, 2017 | 199 | 2017 |
| Scaling computational genomics to millions of individuals with GPUs A Taylor-Weiner, F Aguet, NJ Haradhvala, S Gosai, S Anand, J Kim, ... Genome biology 20, 1-5, 2019 | 180 | 2019 |
| Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease H Zhang, C Xue, R Shah, K Bermingham, CC Hinkle, W Li, A Rodrigues, ... Circulation research 117 (1), 17-28, 2015 | 148 | 2015 |
| Global analysis of the RNA-protein interaction and RNA secondary structure landscapes of the Arabidopsis nucleus SJ Gosai, SW Foley, D Wang, IM Silverman, N Selamoglu, ADL Nelson, ... Molecular cell 57 (2), 376-388, 2015 | 122 | 2015 |
| The macronuclear genome of Stentor coeruleus reveals tiny introns in a giant cell MM Slabodnick, JG Ruby, SB Reiff, EC Swart, S Gosai, S Prabakaran, ... Current Biology 27 (4), 569-575, 2017 | 119 | 2017 |
| Changes in the transcriptome of human astrocytes accompanying oxidative stress-induced senescence EP Crowe, F Tuzer, BD Gregory, G Donahue, SJ Gosai, J Cohen, ... Frontiers in aging neuroscience 8, 208, 2016 | 114 | 2016 |
| The long noncoding RNA landscape in hypoxic and inflammatory renal epithelial injury J Lin, X Zhang, C Xue, H Zhang, MGS Shashaty, SJ Gosai, N Meyer, ... American Journal of Physiology-Renal Physiology 309 (11), F901-F913, 2015 | 84 | 2015 |
| Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases Y Liu, JF Ferguson, C Xue, RL Ballantyne, IM Silverman, SJ Gosai, ... Arteriosclerosis, thrombosis, and vascular biology 34 (4), 902-912, 2014 | 79 | 2014 |
| Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci X Yu, JW Davenport, KA Urtishak, ML Carillo, SJ Gosai, CP Kolaris, ... Genome research 27 (7), 1238-1249, 2017 | 70 | 2017 |
| Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR–FlowFISH SK Reilly, SJ Gosai, A Gutierrez, A Mackay-Smith, JC Ulirsch, M Kanai, ... Nature genetics 53 (8), 1166-1176, 2021 | 64 | 2021 |
| Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism X Zhang, C Xue, J Lin, JF Ferguson, A Weiner, W Liu, Y Han, C Hinkle, ... Science translational medicine 10 (446), eaar5987, 2018 | 54 | 2018 |
| A global view of RNA-protein interactions identifies post-transcriptional regulators of root hair cell fate SW Foley, SJ Gosai, D Wang, N Selamoglu, AC Sollitti, T Köster, A Steffen, ... Developmental Cell 41 (2), 204-220. e5, 2017 | 53 | 2017 |
| Terpene metabolic engineering via nuclear or chloroplast genomes profoundly and globally impacts off‐target pathways through metabolite signalling EK Pasoreck, J Su, IM Silverman, SJ Gosai, BD Gregory, JS Yuan, ... Plant biotechnology journal 14 (9), 1862-1875, 2016 | 40 | 2016 |
| A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover OS Long, JA Benson, JH Kwak, CJ Luke, SJ Gosai, LP O'Reilly, Y Wang, ... Human molecular genetics 23 (19), 5109-5122, 2014 | 40 | 2014 |
| Multicenter integrated analysis of noncoding CRISPRi screens D Yao, J Tycko, JW Oh, LR Bounds, SJ Gosai, L Lataniotis, ... Nature methods 21 (4), 723-734, 2024 | 27 | 2024 |
Ian M SilvermanRepare TherapeuticsVerified email at reparerx.com