| Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma J Zhao, AX Chen, RD Gartrell, AM Silverman, L Aparicio, T Chu, ... Nature medicine 25 (3), 462-469, 2019 | 771 | 2019 |
| Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential DL Worthley, M Churchill, JT Compton, Y Tailor, M Rao, Y Si, D Levin, ... Cell 160 (1), 269-284, 2015 | 675 | 2015 |
| Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease PA Szabo, HM Levitin, M Miron, ME Snyder, T Senda, J Yuan, YL Cheng, ... Nature communications 10 (1), 4706, 2019 | 653 | 2019 |
| Cross-tissue immune cell analysis reveals tissue-specific features in humans C Domínguez Conde, C Xu, LB Jarvis, DB Rainbow, SB Wells, T Gomes, ... Science 376 (6594), eabl5197, 2022 | 618 | 2022 |
| Single cell nucleic acid detection and analysis XS Xie, K Shiroguchi, PA Sims, TZ Jia US Patent 9,260,753, 2016 | 494 | 2016 |
| Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and human H Pan, C Xue, BJ Auerbach, J Fan, AC Bashore, J Cui, DY Yang, ... Circulation 142 (21), 2060-2075, 2020 | 456 | 2020 |
| Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes K Shiroguchi, TZ Jia, PA Sims, XS Xie Proceedings of the National Academy of Sciences 109 (4), 1347-1352, 2012 | 411 | 2012 |
| Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19 PA Szabo, P Dogra, JI Gray, SB Wells, TJ Connors, SP Weisberg, ... Immunity 54 (4), 797-814. e6, 2021 | 360 | 2021 |
| Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells B Liu, BW Lee, K Nakanishi, A Villasante, R Williamson, J Metz, J Kim, ... Nature biomedical engineering 2 (5), 293-303, 2018 | 332 | 2018 |
| MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma BJ Gill, DJ Pisapia, HR Malone, H Goldstein, L Lei, A Sonabend, J Yun, ... Proceedings of the National Academy of Sciences 111 (34), 12550-12555, 2014 | 324 | 2014 |
| Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations S Affo, A Nair, F Brundu, A Ravichandra, S Bhattacharjee, M Matsuda, ... Cancer cell 39 (6), 866-882. e11, 2021 | 299 | 2021 |
| Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities L Garofano, S Migliozzi, YT Oh, F D’Angelo, RD Najac, A Ko, B Frangaj, ... Nature Cancer 2 (2), 141-156, 2021 | 275 | 2021 |
| Generation and persistence of human tissue-resident memory T cells in lung transplantation ME Snyder, MO Finlayson, TJ Connors, P Dogra, T Senda, E Bush, ... Science immunology 4 (33), eaav5581, 2019 | 267 | 2019 |
| Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts S Bhattacharjee, F Hamberger, A Ravichandra, M Miller, A Nair, S Affo, ... The Journal of clinical investigation 131 (11), 2024 | 250 | 2024 |
| Single-cell analysis of regional differences in adult V-SVZ neural stem cell lineages D Mizrak, HM Levitin, AC Delgado, V Crotet, J Yuan, Z Chaker, ... Cell reports 26 (2), 394-406. e5, 2019 | 235 | 2019 |
| Single-cell transcriptome analysis of lineage diversity in high-grade glioma J Yuan, HM Levitin, V Frattini, EC Bush, DM Boyett, J Samanamud, ... Genome medicine 10, 1-15, 2018 | 223 | 2018 |
| The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma M Venere, C Horbinski, JF Crish, X Jin, A Vasanji, J Major, AC Burrows, ... Science translational medicine 7 (304), 304ra143-304ra143, 2015 | 210 | 2015 |
| Observation of individual microtubule motor steps in living cells with endocytosed quantum dots X Nan, PA Sims, P Chen, XS Xie The Journal of Physical Chemistry B 109 (51), 24220-24224, 2005 | 210 | 2005 |
| Single-cell transcriptomic analysis of tumor heterogeneity HM Levitin, J Yuan, PA Sims Trends in cancer 4 (4), 264-268, 2018 | 186 | 2018 |
| Organelle tracking in a living cell with microsecond time resolution and nanometer spatial precision X Nan, PA Sims, XS Xie ChemPhysChem 9 (5), 707-712, 2008 | 181 | 2008 |
Xiaoliang Sunney XieLee Shau Kee Professor of Peking UniversityVerified email at pku.edu.cn