| Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells H Alam, L Sehgal, ST Kundu, SN Dalal, MM Vaidya Molecular biology of the cell 22 (21), 4068-4078, 2011 | 368 | 2011 |
| KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling KW Wagner, H Alam, SS Dhar, U Giri, N Li, Y Wei, D Giri, T Cascone, ... The Journal of clinical investigation 123 (12), 5231-5246, 2013 | 197 | 2013 |
| KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer H Alam, M Tang, M Maitituoheti, SS Dhar, M Kumar, CY Han, CR Ambati, ... Cancer cell 37 (4), 599-617. e7, 2020 | 187 | 2020 |
| MLL4 is required to maintain broad H3K4me3 peaks and super-enhancers at tumor suppressor genes SS Dhar, D Zhao, T Lin, B Gu, K Pal, SJ Wu, H Alam, J Lv, K Yun, ... Molecular cell 70 (5), 825-841. e6, 2018 | 140 | 2018 |
| CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition D Gallo, JTF Young, J Fourtounis, G Martino, A Álvarez-Quilón, C Bernier, ... Nature 604 (7907), 749-756, 2022 | 136 | 2022 |
| Histone methylation modifiers in cellular signaling pathways H Alam, B Gu, MG Lee Cellular and molecular life sciences 72, 4577-4592, 2015 | 118 | 2015 |
| Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis N Khapare, ST Kundu, L Sehgal, M Sawant, R Priya, P Gosavi, N Gupta, ... PloS one 7 (6), e38561, 2012 | 99 | 2012 |
| Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma H Alam, AV Bhate, P Gangadaran, SS Sawant, S Salot, L Sehgal, ... BMC cancer 12, 1-15, 2012 | 92 | 2012 |
| Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells SS Dhar, H Alam, N Li, KW Wagner, J Chung, YW Ahn, MG Lee Journal of Biological Chemistry 289 (11), 7483-7496, 2014 | 77 | 2014 |
| HP1γ promotes lung adenocarcinoma by downregulating the transcription-repressive regulators NCOR2 and ZBTB7A H Alam, N Li, SS Dhar, SJ Wu, J Lv, K Chen, ER Flores, L Baseler, ... Cancer research 78 (14), 3834-3848, 2018 | 75 | 2018 |
| Loss of keratins 8 and 18 leads to alterations in α6β4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line H Alam, ST Kundu, SN Dalal, MM Vaidya Journal of cell science 124 (12), 2096-2106, 2011 | 73 | 2011 |
| Understanding the role of keratins 8 and 18 in neoplastic potential of breast cancer derived cell lines SV Iyer, PP Dange, H Alam, SS Sawant, AD Ingle, AM Borges, NV Shirsat, ... PloS one 8 (1), e53532, 2013 | 69 | 2013 |
| RP-3500: a novel, potent, and selective ATR inhibitor that is effective in preclinical models as a monotherapy and in combination with PARP inhibitors A Roulston, M Zimmermann, R Papp, A Skeldon, C Pellerin, ... Molecular cancer therapeutics 21 (2), 245-256, 2022 | 65 | 2022 |
| Clinical significance of aberrant vimentin expression in oral premalignant lesions and carcinomas SS Sawant, MM Vaidya, DA Chaukar, H Alam, C Dmello, P Gangadaran, ... Oral diseases 20 (5), 453-465, 2014 | 61 | 2014 |
| Enhancer reprogramming confers dependence on glycolysis and IGF signaling in KMT2D mutant melanoma M Maitituoheti, EZ Keung, M Tang, L Yan, H Alam, G Han, AK Singh, ... Cell reports 33 (3), 2020 | 55 | 2020 |
| Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients C Dmello, S Sawant, H Alam, P Gangadaran, S Mogre, R Tiwari, ... PLoS One 12 (2), e0172559, 2017 | 52 | 2017 |
| Loss of keratin 8 phosphorylation leads to increased tumor progression and correlates with clinico-pathological parameters of OSCC patients H Alam, P Gangadaran, AV Bhate, DA Chaukar, SS Sawant, R Tiwari, ... PLoS One 6 (11), e27767, 2011 | 47 | 2011 |
| Vimentin-mediated regulation of cell motility through modulation of beta4 integrin protein levels in oral tumor derived cells C Dmello, S Sawant, H Alam, P Gangadaran, R Tiwari, H Dongre, N Rana, ... The international journal of biochemistry & cell biology 70, 161-172, 2016 | 40 | 2016 |
| 14-3-3γ-mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo L Sehgal, A Mukhopadhyay, A Rajan, N Khapare, M Sawant, SS Vishal, ... Journal of cell science 127 (10), 2174-2188, 2014 | 29 | 2014 |
| Case scenario: pain-associated respiratory failure in chest trauma Y Ahn, K Gorlinger, H Alam, M Eikermann Anaesthesiology 118, 701-8, 2013 | 24 | 2013 |
Shilpa S Dhar, Ph.D.Instructor, MD Anderson Cancer CenterVerified email at mdanderson.org
