The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL MR Wills, AJ Carmichael, K Mynard, X Jin, MP Weekes, B Plachter, ... Journal of virology 70 (11), 7569-7579, 1996 | 899 | 1996 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 843 | 2021 |
Sensitivity of SARS-CoV-2 B. 1.1. 7 to mRNA vaccine-elicited antibodies DA Collier, A De Marco, IATM Ferreira, B Meng, RP Datir, AC Walls, ... Nature 593 (7857), 136-141, 2021 | 735 | 2021 |
Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes NT Ingolia, GA Brar, N Stern-Ginossar, MS Harris, GJS Talhouarne, ... Cell reports 8 (5), 1365-1379, 2014 | 706 | 2014 |
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 DA Collier, IATM Ferreira, P Kotagiri, RP Datir, EY Lim, E Touizer, B Meng, ... Nature 596 (7872), 417-422, 2021 | 703 | 2021 |
Functional Heterogeneity and High Frequencies of Cytomegalovirus-Specific CD8+ T Lymphocytes in Healthy Seropositive Donors GMA Gillespie, MR Wills, V Appay, C O'Callaghan, M Murphy, N Smith, ... Journal of virology 74 (17), 8140-8150, 2000 | 623 | 2000 |
Human cytomegalovirus immunity and immune evasion SE Jackson, GM Mason, MR Wills Virus research 157 (2), 151-160, 2011 | 348 | 2011 |
Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease L Bergamaschi, F Mescia, L Turner, AL Hanson, P Kotagiri, BJ Dunmore, ... Immunity 54 (6), 1257-1275. e8, 2021 | 326 | 2021 |
Identification of naive or antigen-experienced human CD8+ T cells by expression of costimulation and chemokine receptors: analysis of the human cytomegalovirus-specific CD8+ T … MR Wills, G Okecha, MP Weekes, MK Gandhi, PJG Sissons, ... The Journal of Immunology 168 (11), 5455-5464, 2002 | 285 | 2002 |
The memory cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus infection contains individual peptide-specific CTL clones that have undergone extensive expansion in vivo MP Weekes, MR Wills, KIM Mynard, AJ Carmichael, JGP Sissons Journal of virology 73 (3), 2099-2108, 1999 | 263 | 1999 |
Human virus-specific CD8+ CTL clones revert from CD45ROhigh to CD45RAhigh in vivo: CD45RAhighCD8+ T cells comprise both naive and memory cells MR Wills, AJ Carmichael, MP Weekes, K Mynard, G Okecha, R Hicks, ... The Journal of Immunology 162 (12), 7080-7087, 1999 | 236 | 1999 |
Down-regulation of NKG2D and NKp80 ligands by Kaposi's sarcoma-associated herpesvirus K5 protects against NK cell cytotoxicity M Thomas, JM Boname, S Field, S Nejentsev, M Salio, V Cerundolo, ... Proceedings of the National Academy of Sciences 105 (5), 1656-1661, 2008 | 232 | 2008 |
CMV and Immunosenescence: from basics to clinics R Solana, R Tarazona, AE Aiello, AN Akbar, V Appay, M Beswick, ... Immunity & Ageing 9, 1-9, 2012 | 217 | 2012 |
Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis MR Wills, O Ashiru, MB Reeves, G Okecha, J Trowsdale, P Tomasec, ... The Journal of Immunology 175 (11), 7457-7465, 2005 | 197 | 2005 |
Rapid CD8+ T cell repertoire focusing and selection of high-affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus EK Day, AJ Carmichael, IJM Ten Berge, ECP Waller, JG Sissons, ... The Journal of Immunology 179 (5), 3203-3213, 2007 | 191 | 2007 |
Latency and reactivation of human cytomegalovirus JGP Sissons, M Bain, MR Wills Journal of Infection 44 (2), 73-77, 2002 | 180 | 2002 |
Human CD28− CD8+ T cells contain greatly expanded functional virus-specific memory CTL clones MP Weekes, AJ Carmichael, MR Wills, K Mynard, JG Sissons The Journal of Immunology 162 (12), 7569-7577, 1999 | 178 | 1999 |
NKG2D Ligand MICA Is Retained in the cis-Golgi Apparatus by Human Cytomegalovirus Protein UL142 O Ashiru, NJ Bennett, LH Boyle, M Thomas, J Trowsdale, MR Wills Journal of virology 83 (23), 12345-12354, 2009 | 162 | 2009 |
Large clonal expansions of human virus‐specific memory cytotoxic T lymphocytes within the CD57+ CD28– CD8+ T‐cell population MP Weekes, MR Wills, K Mynard, R Hicks, JGP Sissons, AJ Carmichael Immunology 98 (3), 443-449, 1999 | 159 | 1999 |
The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies? MR Wills, E Poole, B Lau, B Krishna, JH Sinclair Cellular & molecular immunology 12 (2), 128-138, 2015 | 158 | 2015 |