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Praveen Kokkonda
Praveen Kokkonda
Temple University
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Year
Proteolysis-targeting chimeras with reduced off-targets
TM Nguyen, V Sreekanth, A Deb, P Kokkonda, PK Tiwari, KA Donovan, ...
Nature chemistry 16 (2), 218-228, 2024
362024
Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication
S Munagala, G Sirasani, P Kokkonda, M Phadke, N Krynetskaia, P Lu, ...
Bioorganic & Medicinal Chemistry 22 (3), 1148-1155, 2014
362014
Synthesis and Biological Evaluation of Pentacyclic Strychnos Alkaloids as Selective Modulators of the ABCC10 (MRP7) Efflux Pump
CN Teijaro, S Munagala, S Zhao, G Sirasani, P Kokkonda, EV Malofeeva, ...
Journal of medicinal chemistry 57 (24), 10383-10390, 2014
282014
Native zinc catalyzes selective and traceless release of small molecules in β-cells
M Lee, B Maji, D Manna, S Kahraman, RM Elgamal, J Small, P Kokkonda, ...
Journal of the American Chemical Society 142 (14), 6477-6482, 2020
252020
Biomimetic Total Syntheses of (−)‐Leucoridines A and C through the Dimerization of (−)‐Dihydrovalparicine
P Kokkonda, KR Brown, TJ Seguin, SE Wheeler, S Vaddypally, MJ Zdilla, ...
Angewandte Chemie 127 (43), 12823-12826, 2015
232015
Chemogenetic system demonstrates that Cas9 longevity impacts genome editing outcomes
V Sreekanth, Q Zhou, P Kokkonda, HC Bermudez-Cabrera, D Lim, ...
ACS Central Science 6 (12), 2228-2237, 2020
192020
Continuous evolution of compact protein degradation tags regulated by selective molecular glues
JAM Mercer, SJ DeCarlo, SS Roy Burman, V Sreekanth, AT Nelson, ...
Science 383 (6688), eadk4422, 2024
172024
Total Syntheses of (–)-Alstolucines A, B, and F,(–)-Echitamidine, and (–)-N-Demethylalstogucine
CN Teijaro, S Zhao, P Kokkonda, RB Andrade
Synthesis 47 (11), 1547-1556, 2015
172015
Total Synthesis of (+)-epi-Condyfoline
P Kokkonda, RB Andrade
Organic letters 21 (23), 9594-9597, 2019
122019
A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules
D Lim, Q Zhou, KJ Cox, BK Law, M Lee, P Kokkonda, V Sreekanth, ...
Nature cell biology 24 (12), 1766-1775, 2022
92022
Diversity-oriented synthesis encoded by deoxyoligonucleotides
L Hudson, JW Mason, MV Westphal, MJR Richter, JR Thielman, BK Hua, ...
Nature communications 14 (1), 4930, 2023
72023
Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation
CJ Arp, M Reynders, V Sreekanth, P Kokkonda, M Pagano, A Choudhary, ...
bioRxiv, 2023
22023
Total Synthesis of Strychnos and Aspidospermatan Alkaloids
P Kokkonda
Theses and Dissertations, 2017
22017
Asymmetric synthesis of Strychnos alkaloids
RB Andrade, P Kokkonda, S Munagala, S Zhao, G Sirasani
Abstracts of Papers of the American Chemical Society 244, 2012
12012
Inhibitors of rna-guided nucleases and uses thereof
A Choudhary, D Lim, Z Qingxuan, K Cox, B Law, LEE Miseon, ...
US Patent App. 18/361,352, 2024
2024
Multi-functional chimeric molecules
A Choudhary, LAI Sophia, V Shoba, P Kokkonda, DM GODAGE, ...
US Patent App. 17/791,811, 2023
2023
Late‐Stage C H Functionalizations Directed by Nickel Catalysis and Its Implications on Total Synthesis of Natural Products
P Kokkonda, A Deb
Handbook of CH‐Functionalization, 1-33, 2022
2022
Novel nucleic acid modifiers
A Choudhary, D Lim, P Kokkonda, LAI Sophia, LEE Miseon
US Patent App. 17/601,052, 2022
2022
Novel nucleic acid modifiers
A Choudhary, D Lim, P Kokkonda, LAI Sophia
US Patent App. 17/372,406, 2022
2022
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
A Choudhary, Z Qingxuan, P Kokkonda
2020
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