Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer WP McGuire, WJ Hoskins, MF Brady, PR Kucera, EE Partridge, KY Look, ... New England Journal of Medicine 334 (1), 1-6, 1996 | 3664 | 1996 |
Characterization of a selective and potent antagonist of human P2X7 receptors, AZ11645373 L Stokes, LH Jiang, L Alcaraz, J Bent, K Bowers, M Fagura, M Furber, ... British journal of pharmacology 149 (7), 880-887, 2006 | 176 | 2006 |
Antagonists of the P2X7 Receptor. From Lead Identification to Drug Development SD Guile, L Alcaraz, TN Birkinshaw, KC Bowers, MR Ebden, M Furber, ... Journal of medicinal chemistry 52 (10), 3123-3141, 2009 | 168 | 2009 |
A palladium‐catalyzed synthesis of amidines from aryl halides CG Saluste, RJ Whitby, M Furber Angewandte Chemie International Edition 39 (22), 4156-4158, 2000 | 158 | 2000 |
Palladium-catalysed synthesis of imidates, thioimidates and amidines from aryl halides CG Saluste, RJ Whitby, M Furber Tetrahedron Letters 42 (35), 6191-6194, 2001 | 91 | 2001 |
Novel P2X7 receptor antagonists L Alcaraz, A Baxter, J Bent, K Bowers, M Braddock, D Cladingboel, ... Bioorganic & medicinal chemistry letters 13 (22), 4043-4046, 2003 | 74 | 2003 |
Cathepsin C inhibitors: property optimization and identification of a clinical candidate M Furber, AK Tiden, P Gardiner, A Mete, R Ford, I Millichip, L Stein, ... Journal of Medicinal Chemistry 57 (6), 2357-2367, 2014 | 73 | 2014 |
The methyl ester of a new gibberellin, GA73: the principal antheridiogen. dta in Lygodium japonicum H Yumane, Y Satoh, K Nohara, M Nakayama, N Murofushi, N Takahashi, ... Tetrahedron letters 29 (32), 3959-3962, 1988 | 69 | 1988 |
Discovery of potent and selective adamantane-based small-molecule P2X7 receptor antagonists/interleukin-1β inhibitors M Furber, L Alcaraz, JE Bent, A Beyerbach, K Bowers, M Braddock, ... Journal of medicinal chemistry 50 (24), 5882-5885, 2007 | 67 | 2007 |
Palladium catalysed synthesis of cyclic amidines and imidates CG Saluste, S Crumpler, M Furber, RJ Whitby Tetrahedron letters 45 (38), 6995-6996, 2004 | 67 | 2004 |
Organocatalytic Enantioselective One‐Pot Four‐Component Ugi‐Type Multicomponent Reaction for the Synthesis of Epoxy‐tetrahydropyrrolo[3,4‐b]pyridin‐5‐ones Y Su, MJ Bouma, L Alcaraz, M Stocks, M Furber, G Masson, J Zhu Chemistry–A European Journal 18 (40), 12624-12627, 2012 | 62 | 2012 |
Synthetic FKBP12 ligands. Design and synthesis of pyranose replacements. TN Birkenshaw, MV Caffrey, DE Cladingboel, ME Cooper, DK Donald, ... Bioorganic & Medicinal Chemistry Letters 4 (21), 2501-2506, 1994 | 60 | 1994 |
Synthesis and study of a non macrocyclic FK506 derivative SJ Teague, ME Cooper, DK Donald, M Furber Bioorganic and Medicinal Chemistry Letters 4, 1581-1581, 1994 | 60 | 1994 |
Conversion of gibberellin A7 into antheridic acid, the antheridium inducing factor from the fern Anemia phyllitidis: a new protocol for controlled 1, 2-bond shifts M Furber, LN Mander Journal of the American Chemical Society 109 (21), 6389-6396, 1987 | 59 | 1987 |
Identification of antheridiogens in Lygodium circinnatum and Lygodium flexuosum T Yamauchi, N Oyama, H Yamane, N Murofushi, H Schraudolf, M Pour, ... Plant Physiology 111 (3), 741-745, 1996 | 57 | 1996 |
Synthesis and evaluation of dual domain macrocyclic FKBP12 ligands. MV Caffrey, DE Cladingboel, ME Cooper, DK Donald, M Furber, ... Bioorganic & Medicinal Chemistry Letters 4 (21), 2507-2510, 1994 | 57 | 1994 |
Studies relating to the immunosuppressive activity of FK506 M Furber, ME Cooper, DK Donald Tetrahedron letters 34 (8), 1351-1354, 1993 | 57 | 1993 |
The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro A Agrawal, KA Buckley, K Bowers, M Furber, JA Gallagher, A Gartland Purinergic signalling 6, 307-315, 2010 | 53 | 2010 |
The discovery of MMP7 inhibitors exploiting a novel selectivity trigger K Edman, M Furber, P Hemsley, C Johansson, G Pairaudeau, J Petersen, ... ChemMedChem 6 (5), 769-773, 2011 | 50 | 2011 |
Kaurenoids and gibberellins, including the newly characterized gibberellin A88, in developing apple seeds P Hedden, GV Hoad, P Gaskin, MJ Lewis, JR Green, M Furber, ... Phytochemistry 32 (2), 231-237, 1993 | 48 | 1993 |