| MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment J Bernhagen, R Krohn, H Lue, JL Gregory, A Zernecke, RR Koenen, ... Nature medicine 13 (5), 587-596, 2007 | 1498 | 2007 |
| Cytokines and atherosclerosis: a comprehensive review of studies in mice R Kleemann, S Zadelaar, T Kooistra Cardiovascular research 79 (3), 360-376, 2008 | 977 | 2008 |
| Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1 R Kleemann, A Hausser, G Geiger, R Mischke, A Burger-Kentischer, ... Nature 408 (6809), 211-216, 2000 | 763 | 2000 |
| Mouse models for atherosclerosis and pharmaceutical modifiers S Zadelaar, R Kleemann, L Verschuren, J de Vries-Van der Weij, ... Arteriosclerosis, thrombosis, and vascular biology 27 (8), 1706-1721, 2007 | 710 | 2007 |
| Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology W Liang, AL Menke, A Driessen, GH Koek, JH Lindeman, R Stoop, ... PloS one 9 (12), e115922, 2014 | 595 | 2014 |
| Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease H Lue, R Kleemann, T Calandra, T Roger, J Bernhagen Microbes and infection 4 (4), 449-460, 2002 | 515 | 2002 |
| Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models R Kleemann, L Verschuren, M Morrison, S Zadelaar, MJ van Erk, ... Atherosclerosis 218 (1), 44-52, 2011 | 477 | 2011 |
| Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis A Burger-Kentischer, H Goebel, R Seiler, G Fraedrich, HE Schaefer, ... Circulation 105 (13), 1561-1566, 2002 | 400 | 2002 |
| Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase R Kleemann, A Kapurniotu, RW Frank, A Gessner, R Mischke, O Flieger, ... Journal of molecular biology 280 (1), 85-102, 1998 | 390 | 1998 |
| The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is … S Mandard, F Zandbergen, NS Tan, P Escher, D Patsouris, W Koenig, ... Journal of Biological Chemistry 279 (33), 34411-34420, 2004 | 355 | 2004 |
| High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice RA van der Heijden, F Sheedfar, MC Morrison, PPH Hommelberg, D Kor, ... Aging (Albany NY) 7 (4), 256, 2015 | 329 | 2015 |
| Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and … JHN Lindeman, H Abdul-Hussien, JH van Bockel, R Wolterbeek, ... Circulation 119 (16), 2209-2216, 2009 | 296 | 2009 |
| Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis R Kleemann, L Verschuren, MJ Van Erk, Y Nikolsky, NHP Cnubben, ... Genome biology 8, 1-16, 2007 | 292 | 2007 |
| Fibrates down-regulate IL-1–stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB–C/EBP-β complex formation R Kleemann, PP Gervois, L Verschuren, B Staels, HMG Princen, ... Blood, The Journal of the American Society of Hematology 101 (2), 545-551, 2003 | 291 | 2003 |
| Global suppression of IL-6-induced acute phase response gene expression after chronic in vivo treatment with the peroxisome proliferator-activated receptor-α activator fenofibrate P Gervois, R Kleemann, A Pilon, F Percevault, W Koenig, B Staels, ... Journal of Biological Chemistry 279 (16), 16154-16160, 2004 | 281 | 2004 |
| Collagen degradation in the abdominal aneurysm: a conspiracy of matrix metalloproteinase and cysteine collagenases H Abdul-Hussien, RGV Soekhoe, E Weber, JH von der Thüsen, ... The American journal of pathology 170 (3), 809-817, 2007 | 248 | 2007 |
| Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro R Kleemann, L Verschuren, BJ de Rooij, J Lindeman, MM de Maat, ... Blood 103 (11), 4188-4194, 2004 | 246 | 2004 |
| Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol–lowering effect in APOE* 3-Leiden transgenic mice: evidence for … R Kleemann, HMG Princen, JJ Emeis, JW Jukema, RD Fontijn, ... Circulation 108 (11), 1368-1374, 2003 | 239 | 2003 |
| Negative regulation of human fibrinogen gene expression by peroxisome proliferator-activated receptor α agonists via inhibition of CCAAT box/enhancer-binding protein β P Gervois, N Vu-Dac, R Kleemann, M Kockx, G Dubois, B Laine, V Kosykh, ... Journal of Biological Chemistry 276 (36), 33471-33477, 2001 | 205 | 2001 |
| Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro K Bellmann, A Wenz, J Radons, V Burkart, R Kleemann, H Kolb J Clin Invest 95, 2840-2845, 1995 | 204 | 1995 |
T KooistraTNO Dept. Metabolic Health Research Leiden The NetherlandsVerified email at tno.nl