| Therapeutic antibodies: successes, limitations and hopes for the future P Chames, M Van Regenmortel, E Weiss, D Baty British journal of pharmacology 157 (2), 220-233, 2009 | 1799 | 2009 |
| A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences J Smith, S Grizot, S Arnould, A Duclert, JC Epinat, P Chames, J Prieto, ... Nucleic acids research 34 (22), e149-e149, 2006 | 490 | 2006 |
| Bispecific antibodies for cancer therapy: the light at the end of the tunnel? P Chames, D Baty MAbs 1 (6), 539-547, 2009 | 481 | 2009 |
| Natural and designer binding sites made by phage display technology HR Hoogenboom, P Chames Immunology today 21 (8), 371-378, 2000 | 406 | 2000 |
| A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells JC Epinat, S Arnould, P Chames, P Rochaix, D Desfontaines, C Puzin, ... Nucleic acids research 31 (11), 2952-2962, 2003 | 404 | 2003 |
| Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets S Arnould, P Chames, C Perez, E Lacroix, A Duclert, JC Epinat, F Stricher, ... Journal of molecular biology 355 (3), 443-458, 2006 | 272 | 2006 |
| Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR RA Willemsen, MEM Weijtens, C Ronteltap, Z Eshhar, JW Gratama, ... Gene therapy 7 (16), 1369-1377, 2000 | 232 | 2000 |
| Oriented conjugates of single-domain antibodies and quantum dots: toward a new generation of ultrasmall diagnostic nanoprobes A Sukhanova, K Even-Desrumeaux, A Kisserli, T Tabary, B Reveil, ... Nanomedicine: nanotechnology, biology and medicine 8 (4), 516-525, 2012 | 211 | 2012 |
| Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof S Arnould, S Bruneau, JP Cabaniols, P Chames, A Choulika, ... US Patent App. 10/543,557, 2006 | 202 | 2006 |
| Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1–MAGE-A1 from a nonimmunized phage-Fab library P Chames, SE Hufton, PG Coulie, B Uchanska-Ziegler, HR Hoogenboom Proceedings of the National Academy of Sciences 97 (14), 7969-7974, 2000 | 188 | 2000 |
| Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells directed … A Lev, G Denkberg, CJ Cohen, M Tzukerman, KL Skorecki, P Chames, ... Cancer research 62 (11), 3184-3194, 2002 | 136 | 2002 |
| Nanobody engineering: toward next generation immunotherapies and immunoimaging of cancer T Chanier, P Chames Antibodies 8 (1), 13, 2019 | 133 | 2019 |
| Custom-made meganuclease and use thereof S Arnould, S Bruneau, JP Cabaniols, P Chames, A Choulika, ... US Patent App. 10/543,556, 2006 | 124 | 2006 |
| A phage display selected fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes RA Willemsen, R Debets, E Hart, HR Hoogenboom, RLH Bolhuis, ... Gene therapy 8 (21), 1601-1608, 2001 | 123 | 2001 |
| Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC-restricted T cell receptor-like … G Denkberg, CJ Cohen, A Lev, P Chames, HR Hoogenboom, Y Reiter Proceedings of the National Academy of Sciences 99 (14), 9421-9426, 2002 | 121 | 2002 |
| TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity P Chames, RA Willemsen, G Rojas, D Dieckmann, L Rem, G Schuler, ... The Journal of Immunology 169 (2), 1110-1118, 2002 | 115 | 2002 |
| Highly sensitive single domain antibody–quantum dot conjugates for detection of HER2 biomarker in lung and breast cancer cells TY Rakovich, OK Mahfoud, BM Mohamed, A Prina-Mello, ... ACS nano 8 (6), 5682-5695, 2014 | 107 | 2014 |
| Isolation and characterization of anti-FcγRIII (CD16) llama single-domain antibodies that activate natural killer cells G Behar, S Sibéril, A Groulet, P Chames, M Pugniere, C Boix, ... Protein Engineering, Design & Selection 21 (1), 1-10, 2008 | 107 | 2008 |
| In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombination P Chames, JC Epinat, S Guillier, A Patin, E Lacroix, F Paˆques Nucleic acids research 33 (20), e178-e178, 2005 | 103 | 2005 |
| Genetic engineering of T cell specificity for immunotherapy of cancer RA Willemsen, R Debets, P Chames, RLH Bolhuis Human Immunology 64 (1), 56-68, 2003 | 101 | 2003 |
Igor NabievLaboratoire BioSpecT (Translational Biospectroscopy), Université de Reims ChampagneVerified email at univ-reims.fr