Articles with public access mandates - Matthias GeyerLearn more
Available somewhere: 145
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
C Venegas, S Kumar, BS Franklin, T Dierkes, R Brinkschulte, D Tejera, ...
Nature 552 (7685), 355-361, 2017
Mandates: German Research Foundation
The RNA polymerase II carboxy-terminal domain (CTD) code
D Eick, M Geyer
Chemical reviews 113 (11), 8456-8490, 2013
Mandates: German Research Foundation
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr, LM Jenster, ...
Science 371 (6530), eabe6230, 2021
Mandates: US Department of Energy, Bill & Melinda Gates Foundation, US National …
NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
A Stutz, CC Kolbe, R Stahl, GL Horvath, BS Franklin, O van Ray, ...
Journal of Experimental Medicine 214 (6), 1725-1736, 2017
Mandates: German Research Foundation, European Commission
Formins as effector proteins of Rho GTPases
S Kühn, M Geyer
Small GTPases 5 (3), e983876, 2014
Mandates: German Research Foundation
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
T Zhang, N Kwiatkowski, CM Olson, SE Dixon-Clarke, BJ Abraham, ...
Nature chemical biology 12 (10), 876-884, 2016
Mandates: US National Institutes of Health, Genome Canada, German Research Foundation …
The control of HIV transcription: keeping RNA polymerase II on track
M Ott, M Geyer, Q Zhou
Cell host & microbe 10 (5), 426-435, 2011
Mandates: US National Institutes of Health, German Research Foundation
Fifteen formins for an actin filament: a molecular view on the regulation of human formins
A Schönichen, M Geyer
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (2), 152-163, 2010
Mandates: German Research Foundation
CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer
SF Johnson, C Cruz, AK Greifenberg, S Dust, DG Stover, D Chi, ...
Cell reports 17 (9), 2367-2381, 2016
Mandates: US National Institutes of Health, National Health and Medical Research …
Rational discovery of molecular glue degraders via scalable chemical profiling
C Mayor-Ruiz, S Bauer, M Brand, Z Kozicka, M Siklos, H Imrichova, ...
Nature chemical biology 16 (11), 1199-1207, 2020
Mandates: Austrian Science Fund, European Molecular Biology Laboratory, European …
Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation
F Itzen, AK Greifenberg, CA Bösken, M Geyer
Nucleic acids research 42 (12), 7577-7590, 2014
Mandates: German Research Foundation
FMNL2 drives actin-based protrusion and migration downstream of Cdc42
J Block, D Breitsprecher, S Kühn, M Winterhoff, F Kage, R Geffers, ...
Current Biology 22 (11), 1005-1012, 2012
Mandates: German Research Foundation
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation
M Krajewska, R Dries, AV Grassetti, S Dust, Y Gao, H Huang, B Sharma, ...
Nature communications 10 (1), 1757, 2019
Mandates: US National Institutes of Health
Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition
N Czudnochowski, CA Bösken, M Geyer
Nature communications 3 (1), 842, 2012
Mandates: German Research Foundation
The structure and substrate specificity of human Cdk12/Cyclin K
CA Bösken, L Farnung, C Hintermair, M Merzel Schachter, ...
Nature communications 5 (1), 3505, 2014
Mandates: US National Institutes of Health, German Research Foundation
Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3
IV Hochheiser, M Pilsl, G Hagelueken, J Moecking, M Marleaux, ...
Nature 604 (7904), 184-189, 2022
Mandates: German Research Foundation
Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution
F Vollmuth, W Blankenfeldt, M Geyer
Journal of Biological Chemistry 284 (52), 36547-36556, 2009
Mandates: German Research Foundation
Structural and functional analysis of the Cdk13/Cyclin K complex
AK Greifenberg, D Hönig, K Pilarova, R Düster, K Bartholomeeusen, ...
Cell reports 14 (2), 320-331, 2016
Mandates: German Research Foundation
Conformational states of human rat sarcoma (Ras) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis
M Spoerner, C Hozsa, JA Poetzl, K Reiss, P Ganser, M Geyer, ...
Journal of biological chemistry 285 (51), 39768-39778, 2010
Mandates: German Research Foundation
P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates
M Sansó, RS Levin, JJ Lipp, VYF Wang, AK Greifenberg, EM Quezada, ...
Genes & development 30 (1), 117-131, 2016
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, German …
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