| Dead Cas systems: types, principles, and applications S Brezgin, A Kostyusheva, D Kostyushev, V Chulanov International journal of molecular sciences 20 (23), 6041, 2019 | 129 | 2019 |
| CRISPR-Cas systems for diagnosing infectious diseases A Kostyusheva, S Brezgin, Y Babin, I Vasilyeva, D Glebe, D Kostyushev, ... Methods 203, 431-446, 2022 | 117 | 2022 |
| Orthologous CRISPR/Cas9 systems for specific and efficient degradation of covalently closed circular DNA of hepatitis B virus D Kostyushev, S Brezgin, A Kostyusheva, D Zarifyan, I Goptar, ... Cellular and Molecular Life Sciences 76 (9), 1779-1794, 2019 | 83 | 2019 |
| Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9 D Kostyushev, A Kostyusheva, S Brezgin, D Zarifyan, A Utkina, I Goptar, ... Scientific reports 9 (1), 1847, 2019 | 55 | 2019 |
| Host-cell interactions in HBV infection and pathogenesis: the emerging role of m6A modification A Kostyusheva, S Brezgin, D Glebe, D Kostyushev, V Chulanov Emerging Microbes & Infections 10 (1), 2264-2275, 2021 | 54 | 2021 |
| Gene editing by extracellular vesicles D Kostyushev, A Kostyusheva, S Brezgin, V Smirnov, E Volchkova, ... International Journal of Molecular Sciences 21 (19), 7362, 2020 | 54 | 2020 |
| Technological aspects of manufacturing and analytical control of biological nanoparticles S Brezgin, A Parodi, A Kostyusheva, N Ponomareva, A Lukashev, ... Biotechnology Advances 64, 108122, 2023 | 28 | 2023 |
| Biomimetic approaches for targeting tumor-promoting inflammation A Parodi, D Kostyushev, S Brezgin, A Kostyusheva, T Borodina, R Akasov, ... Seminars in Cancer Biology 86, 555-567, 2022 | 25 | 2022 |
| ATM and ATR expression potentiates HBV replication and contributes to reactivation of HBV infection upon DNA damage A Kostyusheva, S Brezgin, E Bayurova, I Gordeychuk, M Isaguliants, ... Viruses 11 (11), 997, 2019 | 24 | 2019 |
| Small molecular inhibitors of DNA double strand break repair pathways increase the ANTI-HBV activity of CRISPR/Cas9 AP Kostyusheva, DS Kostyushev, SA Brezgin, DN Zarifyan, EV Volchkova, ... Molecular Biology 53, 274-285, 2019 | 24 | 2019 |
| Clinical implications of hepatitis B virus RNA and covalently closed circular DNA in monitoring patients with chronic hepatitis B today with a gaze into the future: the field … A Kostyusheva, D Kostyushev, S Brezgin, E Volchkova, V Chulanov Genes 9 (10), 483, 2018 | 21 | 2018 |
| Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR-Cas9 D Kostyushev, A Kostyusheva, S Brezgin, N Ponomareva, NF Zakirova, ... Molecular Therapy-Nucleic Acids 31, 482-493, 2023 | 19 | 2023 |
| Immunity and viral infections: modulating antiviral response via CRISPR–Cas systems S Brezgin, A Kostyusheva, E Bayurova, E Volchkova, V Gegechkori, ... Viruses 13 (7), 1373, 2021 | 17 | 2021 |
| Replenishment of hepatitis B virus cccDNA pool is restricted by baseline expression of host restriction factors in vitro S Brezgin, A Kostyusheva, E Bayurova, I Gordeychuk, M Isaguliants, ... Microorganisms 7 (11), 533, 2019 | 15 | 2019 |
| Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus D Kostyushev, S Brezgin, A Kostyusheva, N Ponomareva, E Bayurova, ... Molecular Therapy-Nucleic Acids 32, 478-493, 2023 | 13 | 2023 |
| CRISPR screening: molecular tools for studying virus–host interactions V Chulanov, A Kostyusheva, S Brezgin, N Ponomareva, V Gegechkori, ... Viruses 13 (11), 2258, 2021 | 13 | 2021 |
| Hydroxychloroquine enhances cytotoxic properties of extracellular vesicles and extracellular vesicle–mimetic nanovesicles loaded with chemotherapeutics S Brezgin, A Kostyusheva, N Ponomareva, E Bayurova, A Kondrashova, ... Pharmaceutics 15 (2), 534, 2023 | 10 | 2023 |
| Clearing of foreign episomal DNA from human cells by CRISPRa-mediated activation of cytidine deaminases S Brezgin, A Kostyusheva, N Ponomareva, V Volia, I Goptar, A Nikiforova, ... International journal of molecular sciences 21 (18), 6865, 2020 | 10 | 2020 |
| Overexpression of DNA-methyltransferases in persistency of cccDNA pool in chronic hepatitis B DS Kostyushev, AP Zueva, SA Brezgin, AD Lipatnikov, VN Simirskii, ... Terapevticheskii arkhiv 89 (11), 21-26, 2017 | 10 | 2017 |
| The menace of severe adverse events and deaths associated with viral gene therapy and its potential solution A Kachanov, A Kostyusheva, S Brezgin, I Karandashov, N Ponomareva, ... Medicinal Research Reviews, 2024 | 8 | 2024 |
