| Discovery of β-arrestin–biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy JA Allen, JM Yost, V Setola, X Chen, MF Sassano, M Chen, S Peterson, ... Proceedings of the National Academy of Sciences 108 (45), 18488-18493, 2011 | 392 | 2011 |
| CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling AC Magalhaes, KD Holmes, LB Dale, L Comps-Agrar, D Lee, PN Yadav, ... Nature neuroscience 13 (5), 622-629, 2010 | 256 | 2010 |
| A diarylheptanoid from lesser galangal (Alpinia officinarum) inhibits proinflammatory mediators via inhibition of mitogen-activated protein kinase, p44/42, and transcription … PN Yadav, Z Liu, MM Rafi Journal of Pharmacology and Experimental Therapeutics 305 (3), 925-931, 2003 | 168 | 2003 |
| A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons MS Farrell, Y Pei, Y Wan, PN Yadav, TL Daigle, DJ Urban, HM Lee, ... Neuropsychopharmacology 38 (5), 854-862, 2013 | 151 | 2013 |
| Parallel functional activity profiling reveals valvulopathogens are potent 5-hydroxytryptamine2B receptor agonists: implications for drug safety assessment XP Huang, V Setola, PN Yadav, JA Allen, SC Rogan, BJ Hanson, ... Molecular pharmacology 76 (4), 710-722, 2009 | 136 | 2009 |
| PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors AI Abbas, PN Yadav, WD Yao, MI Arbuckle, SGN Grant, MG Caron, ... Journal of Neuroscience 29 (22), 7124-7136, 2009 | 132 | 2009 |
| Lycopene inhibits LPS‐induced proinflammatory mediator inducible nitric oxide synthase in mouse macrophage cells MM Rafi, PN Yadav, M Reyes Journal of Food Science 72 (1), S069-S074, 2007 | 128 | 2007 |
| Modulation of autoimmune diseases by nitric oxide VK Singh, S Mehrotra, P Narayan, CM Pandey, SS Agarwal Immunologic Research 22, 1-19, 2000 | 120 | 2000 |
| Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation P Kumari, A Srivastava, E Ghosh, R Ranjan, S Dogra, PN Yadav, ... Molecular Biology of the Cell 28 (8), 1003-1010, 2017 | 111 | 2017 |
| Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo PN Yadav, WK Kroeze, MS Farrell, BL Roth Journal of Pharmacology and Experimental Therapeutics 339 (1), 99-105, 2011 | 87 | 2011 |
| The presynaptic component of the serotonergic system is required for clozapine's efficacy PN Yadav, AI Abbas, MS Farrell, V Setola, N Sciaky, XP Huang, ... Neuropsychopharmacology 36 (3), 638-651, 2011 | 71 | 2011 |
| Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases JA Allen, PN Yadav, BL Roth Neuropharmacology 55 (6), 961-968, 2008 | 66 | 2008 |
| Identification of novel β-lactams and pyrrolidinone derivatives as selective Histamine-3 receptor (H3R) modulators as possible anti-obesity agents A Ghoshal, A Kumar, D Yugandhar, C Sona, S Kuriakose, K Nagesh, ... European Journal of Medicinal Chemistry 152, 148-159, 2018 | 55 | 2018 |
| Biased agonism at kappa opioid receptors: Implication in pain and mood disorders S Dogra, PN Yadav European journal of pharmacology 763, 184-190, 2015 | 55 | 2015 |
| Glucosamine inhibits LPS‐induced COX‐2 and iNOS expression in mouse macrophage cells (RAW 264.7) by inhibition of p38‐MAP kinase and transcription factor NF‐κB MM Rafi, PN Yadav, AO Rossi Molecular nutrition & food research 51 (5), 587-593, 2007 | 55 | 2007 |
| Docosahexaenoic acid modulates brain-derived neurotrophic factor via GPR40 in the brain and alleviates diabesity-associated learning and memory deficits in mice C Sona, A Kumar, S Dogra, BA Kumar, D Umrao, PN Yadav Neurobiology of Disease 118, 94-107, 2018 | 52 | 2018 |
| Intestinal epithelial cell–derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K Signaling JR Goldsmith, E Perez-Chanona, PN Yadav, J Whistler, B Roth, C Jobin The American journal of pathology 182 (3), 776-785, 2013 | 47 | 2013 |
| Search of the human proteome for endomorphin-1 and endomorphin-2 precursor proteins A Terskiy, KM Wannemacher, PN Yadav, M Tsai, B Tian, RD Howells Life sciences 81 (23-24), 1593-1601, 2007 | 47 | 2007 |
| A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis. SAK Ghosh E, Srivastava A, Baidya M, Kumari P, Dwivedi H, Nidhi K, Ranjan R ... Nat Nanotechnol, 2017 | 43 | 2017 |
| Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo JA Allen, PN Yadav, V Setola, M Farrell, BL Roth Translational psychiatry 1 (8), e33-e33, 2011 | 39 | 2011 |
BL RothDepartment of Pharmacology, University of North Carolina Medical SchoolVerified email at med.unc.edu