Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans. RJ Reiter, D Tan, JC Mayo, RM Sainz, J Leon, Z Czarnocki Acta Biochimica Polonica 50 (4), 1129-1146, 2003 | 882 | 2003 |
Melatonin mitigates mitochondrial malfunction J Leon, D Acuña‐Castroviejo, G Escames, DX Tan, RJ Reiter Journal of pineal research 38 (1), 1-9, 2005 | 640 | 2005 |
Melatonin, mitochondria, and cellular bioenergetics D Acuña‐Castroviejo, M Martín, M Macías, G Escames, J León, H Khaldy, ... Journal of pineal research 30 (2), 65-74, 2001 | 568 | 2001 |
Melatonin but not vitamins C and E maintains glutathione homeostasis in t‐butyl hydroperoxide‐induced mitochondrial oxidative stress M Martín, M Macías, G Escames, J León, D Acuña-Castroviejo The FASEB Journal 14 (12), 1677-1679, 2000 | 444 | 2000 |
Melatonin and mitochondrial function J Leon, D Acuña-Castroviejo, RM Sainz, JC Mayo, DX Tan, RJ Reiter Life sciences 75 (7), 765-790, 2004 | 439 | 2004 |
Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages JC Mayo, RM Sainz, DX Tan, R Hardeland, J Leon, C Rodriguez, ... Journal of neuroimmunology 165 (1-2), 139-149, 2005 | 436 | 2005 |
Melatonin increases the activity of the oxidative phosphorylation enzymes and the production of ATP in rat brain and liver mitochondria M Martı́n, M Macı́as, J León, G Escames, H Khaldy, D Acuña-Castroviejo The international journal of biochemistry & cell biology 34 (4), 348-357, 2002 | 334 | 2002 |
Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. KU Reiter RJ, Tan DX, Gitto E, Sainz RM, Mayo JC, Leon J, Manchester LC ... Polish Journal of Pharmacology 56 (2), 159-170, 2004 | 309 | 2004 |
When melatonin gets on your nerves: its beneficial actions in experimental models of stroke RJ Reiter, D Tan, J Leon, Ü Kilic, E Kilic Experimental biology and medicine 230 (2), 104-117, 2005 | 273 | 2005 |
Melatonin counteracts lipopolysaccharide‐induced expression and activity of mitochondrial nitric oxide synthase in rats G Escames, J León, M Macías, H Khaldy, D Acuña-Castroviejo The FASEB Journal 17 (8), 1-22, 2003 | 248 | 2003 |
Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism RM Sainz, JC Mayo, D Tan, J León, L Manchester, RJ Reiter The Prostate 63 (1), 29-43, 2005 | 229 | 2005 |
Inhibition of neuronal nitric oxide synthase activity by N1‐acetyl‐5‐methoxykynuramine, a brain metabolite of melatonin J León, G Escames, MI Rodríguez, LC López, V Tapias, A Entrena, ... Journal of neurochemistry 98 (6), 2023-2033, 2006 | 206 | 2006 |
Melatonin, mitochondrial homeostasis and mitochondrial-related diseases D Castroviejo, G Escames, A Carazo, J León, H Khaldy, RJ Reiter Current topics in medicinal chemistry 2 (2), 133-151, 2002 | 201 | 2002 |
Mitochondrial regulation by melatonin and its metabolites D Acuña-Castroviejo, G Escames, J LeÓn, A Carazo, H Khaldy Developments in tryptophan and serotonin metabolism, 549-557, 2003 | 198 | 2003 |
Melatonin counteracts inducible mitochondrial nitric oxide synthase‐dependent mitochondrial dysfunction in skeletal muscle of septic mice G Escames, LC López, V Tapias, P Utrilla, RJ Reiter, AB Hitos, J León, ... Journal of pineal research 40 (1), 71-78, 2006 | 180 | 2006 |
Structure-related inhibition of calmodulin-dependent neuronal nitric-oxide synthase activity by melatonin and synthetic kynurenines J León, M Macías, G Escames, E Camacho, H Khaldy, M Martín, ... Molecular pharmacology 58 (5), 967-975, 2000 | 170 | 2000 |
Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence G Escames, D Acuña‐Castroviejo, LC López, D Tan, MD Maldonado, ... Journal of pharmacy and pharmacology 58 (9), 1153-1165, 2006 | 168 | 2006 |
Calreticulin–melatonin: An unexpected relationship M Macías, G Escames, J Leon, A Coto, Y Sbihi, A Osuna, ... European journal of biochemistry 270 (5), 832-840, 2003 | 165 | 2003 |
Genetic variation in interleukin 28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV‐infected children Á Ruiz‐Extremera, JA Muñoz‐Gámez, MA Salmerón‐Ruiz, PM de Rueda, ... Hepatology 53 (6), 1830-1838, 2011 | 154 | 2011 |
Circadian rhythms of dopamine and dihydroxyphenyl acetic acid in the mouse striatum: effects of pinealectomy and of melatonin treatment H Khaldy, J León, G Escames, L Bikjdaouene, JJ García, ... Neuroendocrinology 75 (3), 201-208, 2002 | 136 | 2002 |