| Fasting-induced transcription factors repress vitamin D bioactivation, a mechanism for vitamin D deficiency in diabetes SM Aatsinki, MS Elkhwanky, O Kummu, M Karpale, M Buler, P Viitala, ... Diabetes 68 (5), 918-931, 2019 | 65 | 2019 |
| Activation of nuclear receptor PXR impairs glucose tolerance and dysregulates GLUT2 expression and subcellular localization in liver F Hassani-Nezhad-Gashti, J Rysä, O Kummu, J Näpänkangas, M Buler, ... Biochemical Pharmacology 148, 253-264, 2018 | 47 | 2018 |
| Activation of pregnane X receptor induces atherogenic lipids and PCSK9 by a SREBP2‐mediated mechanism M Karpale, AJ Käräjämäki, O Kummu, H Gylling, T Hyötyläinen, M Orešič, ... British Journal of Pharmacology 178 (12), 2461-2481, 2021 | 41 | 2021 |
| Nuclear receptor PXR in drug-induced hypercholesterolemia M Karpale, J Hukkanen, J Hakkola Cells 11 (3), 313, 2022 | 28 | 2022 |
| Nutritional status modifies pregnane X receptor regulated transcriptome F Hassani-Nezhad-Gashti, O Kummu, M Karpale, J Rysä, J Hakkola Scientific Reports 9 (1), 16728, 2019 | 17 | 2019 |
| Pregnane X receptor activation remodels glucose metabolism to promote NAFLD development in obese mice M Karpale, O Kummu, O Kärkkäinen, M Lehtonen, J Näpänkangas, ... Molecular metabolism 76, 101779, 2023 | 7 | 2023 |
| Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice T Ala-Nisula, R Halmetoja, H Leinonen, M Kurkela, HR Lipponen, ... Pflügers Archiv-European Journal of Physiology, 1-13, 2024 | 2 | 2024 |
| LIM and SH3 Protein 2 (Lasp2) is a novel PXR target gene in mouse liver A Konzack, M Karpale, T Smutny, M Hassanen, P Lassila, MH Ahonen, ... Molecular Pharmacology, 100019, 2025 | | 2025 |
| Roxadustat alleviates metabolic traits in letrozole-induced PCOS mice N Virtanen, U Saarela, M Karpale, RK Arffman, KA Mäkelä, KH Herzig, ... Biochemical Pharmacology 229, 116522, 2024 | | 2024 |
| PXR agonist rifampicin elevates serum Lp (a) levels substantially T Kotilainen, H Merikallio, O Kummu, M Karpale, H Hautajärvi, J Hakkola, ... Atherosclerosis 395, 2024 | | 2024 |
| Hemoglobin levels are associated with retinal vascular caliber in a middle-aged birth cohort S Sakko, M Karpale, J Tapio, I Leppänen, O Ahokas, V Saarela, ... Scientific Reports 14 (1), 9092, 2024 | | 2024 |
| Nuclear receptor PXR in obesity and its regulation by metabolic status M Karpale University of Oulu, 2021 | | 2021 |
| Toxicogenomic approach to screen potential drug toxicities M Karpale M. Karpale, 2015 | | 2015 |
Jukka HakkolaUniversity of OuluVerified email at oulu.fi