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Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study E Majounie, AE Renton, K Mok, EGP Dopper, A Waite, S Rollinson, ... The Lancet Neurology 11 (4), 323-330, 2012 | 1410 | 2012 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 664 | 2018 |
PINK1 cleavage at position A103 by the mitochondrial protease PARL E Deas, H Plun-Favreau, S Gandhi, H Desmond, S Kjaer, SHY Loh, ... Human molecular genetics 20 (5), 867-879, 2011 | 566 | 2011 |
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis JO Johnson, EP Pioro, A Boehringer, R Chia, H Feit, AE Renton, ... Nature neuroscience 17 (5), 664-666, 2014 | 556 | 2014 |
A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 380 | 2017 |
The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, ... Nature 586 (7831), 735-740, 2020 | 307 | 2020 |
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture R Chia, MS Sabir, S Bandres-Ciga, S Saez-Atienzar, RH Reynolds, ... Nature genetics 53 (3), 294-303, 2021 | 293 | 2021 |
Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation JC Bis, X Jian, BW Kunkle, Y Chen, KL Hamilton-Nelson, WS Bush, ... Molecular psychiatry 25 (8), 1859-1875, 2020 | 265 | 2020 |
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Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response N Moisoi, K Klupsch, V Fedele, P East, S Sharma, A Renton, ... Cell Death & Differentiation 16 (3), 449-464, 2009 | 211 | 2009 |
Extensive genetics of ALS: a population-based study in Italy A Chio, A Calvo, L Mazzini, R Cantello, G Mora, C Moglia, L Corrado, ... Neurology 79 (19), 1983-1989, 2012 | 204 | 2012 |
Repeat Expansion in C9ORF72 in Alzheimer's Disease E Majounie, Y Abramzon, AE Renton, R Perry, SS Bassett, O Pletnikova, ... New England Journal of Medicine 366 (3), 283-284, 2012 | 201 | 2012 |
A genome-wide association study of myasthenia gravis AE Renton, HA Pliner, C Provenzano, A Evoli, R Ricciardi, MA Nalls, ... JAMA neurology 72 (4), 396-404, 2015 | 195 | 2015 |
Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy A Al-Chalabi, A Dürr, NW Wood, MH Parkinson, A Camuzat, JS Hulot, ... PloS one 4 (9), e7114, 2009 | 185 | 2009 |
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The complex genetic architecture of Alzheimer's disease: novel insights and future directions SJ Andrews, AE Renton, B Fulton-Howard, A Podlesny-Drabiniok, ... EBioMedicine 90, 2023 | 162 | 2023 |
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