| A research agenda for aging in China in the 21st century EF Fang, M Scheibye-Knudsen, HJ Jahn, J Li, L Ling, H Guo, X Zhu, ... Ageing Research Reviews 24, 197-205, 2015 | 599 | 2015 |
| NAD+ replenishment improves lifespan and healthspan in ataxia telangiectasia models via mitophagy and DNA repair EF Fang, H Kassahun, DL Croteau, M Scheibye-Knudsen, K Marosi, H Lu, ... Cell Metabolism 24 (4), 566-581, 2016 | 564 | 2016 |
| Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates L Zheng, M Zhou, Z Guo, H Lu, L Qian, H Dai, J Qiu, E Yakubovskaya, ... Molecular Cell 32 (3), 325-336, 2008 | 279 | 2008 |
| MLH1 deficiency-triggered DNA hyperexcision by exonuclease 1 activates the cGAS-STING pathway J Guan, C Lu, Q Jin, H Lu, X Chen, L Tian, Y Zhang, J Ortega, J Zhang, ... Cancer cell 39 (1), 109-121. e5, 2021 | 172 | 2021 |
| A novel OxyR sensor and regulator of hydrogen peroxide stress with one cysteine residue in Deinococcus radiodurans H Chen, G Xu, Y Zhao, B Tian, H Lu, X Yu, Z Xu, N Ying, S Hu, Y Hua PLoS One 3 (2), e1602, 2008 | 131 | 2008 |
| Deinococcus radiodurans PprI switches on DNA damage response and cellular survival networks after radiation damage H Lu, G Gao, G Xu, L Fan, L Yin, B Shen, Y Hua Molecular & Cellular Proteomics 8 (3), 481-494, 2009 | 125 | 2009 |
| DNA polymerase beta participates in mitochondrial DNA repair P Sykora, S Kanno, M Akbari, T Kulikowicz, BA Baptiste, GS Leandro, ... Molecular and cellular biology 37 (16), e00237-17, 2017 | 113 | 2017 |
| WRN regulates pathway choice between classical and alternative non-homologous end joining RA Shamanna, H Lu, JK De Freitas, J Tian, DL Croteau, VA Bohr Nature communications 7 (1), 13785, 2016 | 111 | 2016 |
| RECQL4 promotes DNA end resection in repair of DNA double-strand breaks H Lu, RA Shamanna, G Keijzers, R Anand, LJ Rasmussen, P Cejka, ... Cell Reports 16 (1), 161-173, 2016 | 107 | 2016 |
| RECQL4 in genomic instability and aging DL Croteau, DK Singh, LH Ferrarelli, H Lu, VA Bohr Trends in Genetics 28 (12), 624-631, 2012 | 96 | 2012 |
| Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair H Lu, RA Shamanna, JK de Freitas, M Okur, P Khadka, T Kulikowicz, ... Nature communications 8 (1), 2039, 2017 | 94 | 2017 |
| DNA-PKcs promotes chromatin decondensation to facilitate initiation of the DNA damage response H Lu, J Saha, PJ Beckmann, EA Hendrickson, AJ Davis Nucleic acids research 47 (18), 9467-9479, 2019 | 81 | 2019 |
| DdrB stimulates single-stranded DNA annealing and facilitates RecA-independent DNA repair in Deinococcus radiodurans G Xu, H Lu, L Wang, H Chen, Z Xu, Y Hu, B Tian, Y Hua DNA repair 9 (7), 805-812, 2010 | 69 | 2010 |
| RecO is essential for DNA damage repair in Deinococcus radiodurans G Xu, L Wang, H Chen, H Lu, N Ying, B Tian, Y Hua Journal of Bacteriology 190 (7), 2624-2628, 2008 | 69 | 2008 |
| Protease activity of PprI facilitates DNA damage response: Mn (2+)-dependence and substrate sequence-specificity of the proteolytic reaction Y Wang, Q Xu, H Lu, L Lin, L Wang, H Xu, X Cui, H Zhang, T Li, Y Hua PloS one 10 (3), e0122071, 2015 | 66 | 2015 |
| RECQ helicase RECQL4 participates in non-homologous end joining and interacts with the Ku complex RA Shamanna, DK Singh, H Lu, G Mirey, G Keijzers, B Salles, DL Croteau, ... Carcinogenesis 35 (11), 2415-2424, 2014 | 62 | 2014 |
| Senescence induced by RECQL4 dysfunction contributes to Rothmund–Thomson syndrome features in mice H Lu, EF Fang, P Sykora, T Kulikowicz, Y Zhang, KG Becker, DL Croteau, ... Cell death & disease 5 (5), e1226-e1226, 2014 | 62 | 2014 |
| Human RecQ Helicases in DNA Double-Strand Break Repair H Lu, AJ Davis Frontiers in Cell and Developmental Biology 9, 640755, 2021 | 57 | 2021 |
| RECQL4 helicase has oncogenic potential in sporadic breast cancers A Arora, D Agarwal, TMA Abdel‐Fatah, H Lu, DL Croteau, P Moseley, ... The Journal of pathology 238 (4), 495-501, 2016 | 53 | 2016 |
| DNA binding is essential for PprI function in response to radiation damage in Deinococcus radiodurans H Lu, H Chen, G Xu, AMUH Shah, Y Hua DNA repair 11 (2), 139-145, 2012 | 50 | 2012 |
Deborah L CroteauNational Institute on Aging, NIHVerified email at nih.gov