| Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors JC Zinder, CD Lima Genes & development 31 (2), 88-100, 2017 | 261 | 2017 |
| Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex EM Weick, MR Puno, K Januszyk, JC Zinder, MA DiMattia, CD Lima Cell 173 (7), 1663-1677. e21, 2018 | 138 | 2018 |
| Nuclear RNA exosome at 3.1 Å reveals substrate specificities, RNA paths, and allosteric inhibition of Rrp44/Dis3 JC Zinder, EV Wasmuth, CD Lima Molecular cell 64 (4), 734-745, 2016 | 107 | 2016 |
| Chemically related 4, 5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions MR Wasserman, A Pulk, Z Zhou, RB Altman, JC Zinder, KD Green, ... Nature communications 6 (1), 7896, 2015 | 72 | 2015 |
| Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase EV Wasmuth, JC Zinder, D Zattas, M Das, CD Lima Elife 6, e29062, 2017 | 64 | 2017 |
| Cryo-EM structure of the human CST–Polα/primase complex in a recruitment state SW Cai, JC Zinder, V Svetlov, MW Bush, E Nudler, T Walz, T de Lange Nature Structural & Molecular Biology 29 (8), 813-819, 2022 | 48 | 2022 |
| Allosteric interactions prime androgen receptor dimerization and activation EV Wasmuth, AV Broeck, JR LaClair, EA Hoover, KE Lawrence, ... Molecular Cell 82 (11), 2021-2031. e5, 2022 | 40 | 2022 |
| Shelterin is a dimeric complex with extensive structural heterogeneity JC Zinder, PDB Olinares, V Svetlov, MW Bush, E Nudler, BT Chait, T Walz, ... Proceedings of the National Academy of Sciences 119 (31), e2201662119, 2022 | 29 | 2022 |
| Bacteriophage SPP1 DNA replication strategies promote viral and disable host replication in vitro EM Seco, JC Zinder, CM Manhart, A Lo Piano, CS McHenry, S Ayora Nucleic acids research 41 (3), 1711-1721, 2013 | 27 | 2013 |
| Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome M Das, D Zattas, JC Zinder, EV Wasmuth, J Henri, CD Lima Proceedings of the National Academy of Sciences 118 (14), e2024846118, 2021 | 14 | 2021 |
| Reconstitution of S. cerevisiae RNA Exosome Complexes Using Recombinantly Expressed Proteins JC Zinder, CD Lima The Eukaryotic RNA Exosome: Methods and Protocols, 427-448, 2020 | 1 | 2020 |
| Strategies for generating RNA exosome complexes from recombinant expression hosts EM Weick, JC Zinder, CD Lima The Eukaryotic Rna Exosome: Methods and Protocols, 417-425, 2020 | 1 | 2020 |
| Structure and Activities of the Saccharomyces Cerevisiae Nuclear RNA Exosome JC Zinder Weill Medical College of Cornell University, 2018 | | 2018 |
| In vitro Studies of DNA Replication in Bacillus subtilis and Phage SPP1 JC Zinder Biological Chemistry 275, 28971-28983, 2000 | | 2000 |
Christopher D. Lima, PhDChair, Structural Biology Program, Professor and Member, Sloan Kettering Institute, HHMIVerified email at mskcc.org