| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 13963* | 2016 |
| Regulation of mammalian autophagy in physiology and pathophysiology B Ravikumar, S Sarkar, JE Davies, M Futter, M Garcia-Arencibia, ... Physiological Reviews 90 (4), 1383-1435, 2010 | 2140 | 2010 |
| Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein S Sarkar, JE Davies, Z Huang, A Tunnacliffe, DC Rubinsztein Journal of Biological Chemistry 282 (8), 5641-5652, 2007 | 1292 | 2007 |
| Lithium induces autophagy by inhibiting inositol monophosphatase S Sarkar, RA Floto, Z Berger, S Imarisio, A Cordenier, M Pasco, LJ Cook, ... Journal of Cell Biology 170 (7), 1101-1111, 2005 | 1160 | 2005 |
| Lysosomal positioning coordinates cellular nutrient responses VI Korolchuk, S Saiki, M Lichtenberg, FH Siddiqi, EA Roberts, S Imarisio, ... Nature Cell Biology 13 (4), 453-460, 2011 | 956 | 2011 |
| Novel targets for Huntington's disease in an mTOR-independent autophagy pathway A Williams*, S Sarkar*, P Cuddon, EK Ttofi, S Saiki, FH Siddiqi, L Jahreiss, ... Nature Chemical Biology 4 (5), 295-305, 2008 | 942 | 2008 |
| Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ... Nature Biotechnology 31 (7), 653-658, 2013 | 918 | 2013 |
| Small molecules enhance autophagy and reduce toxicity in Huntington's disease models S Sarkar, EO Perlstein, S Imarisio, S Pineau, A Cordenier, RL Maglathlin, ... Nature Chemical Biology 3 (6), 331-338, 2007 | 706 | 2007 |
| Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies S Sarkar, B Ravikumar, RA Floto, DC Rubinsztein Cell Death and Differentiation 16 (1), 46-56, 2008 | 661 | 2008 |
| In search of an “autophagomometer” DC Rubinsztein, AM Cuervo, B Ravikumar, S Sarkar, V Korolchuk, ... Autophagy 5 (5), 585-589, 2009 | 647 | 2009 |
| Complex inhibitory effects of nitric oxide on autophagy S Sarkar, VI Korolchuk, M Renna, S Imarisio, A Fleming, A Williams, ... Molecular Cell 43 (1), 19-32, 2011 | 423 | 2011 |
| Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers S Sarkar Biochemical Society Transactions 41 (5), 1103-1130, 2013 | 421 | 2013 |
| A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin S Sarkar, G Krishna, S Imarisio, S Saiki, CJ O'Kane, DC Rubinsztein Human Molecular Genetics 17 (2), 170-178, 2008 | 415 | 2008 |
| Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function S Chakrabortee, C Boschetti, LJ Walton, S Sarkar, DC Rubinsztein, ... Proceedings of the National Academy of Sciences 104 (46), 18073-18078, 2007 | 359 | 2007 |
| Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease B Ravikumar, S Imarisio, S Sarkar, CJ O'Kane, DC Rubinsztein Journal of Cell Science 121 (10), 1649-1660, 2008 | 357 | 2008 |
| Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications A Williams, L Jahreiss, S Sarkar, S Saiki, FM Menzies, B Ravikumar, ... Current Topics in Developmental Biology 76, 89-101, 2006 | 351 | 2006 |
| Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease S Sarkar, B Carroll, Y Buganim, D Maetzel, AHM Ng, JP Cassady, ... Cell Reports 5 (5), 1302-1315, 2013 | 336 | 2013 |
| Autophagy, lipophagy and lysosomal lipid storage disorders C Ward, N Martinez-Lopez, EG Otten, B Carroll, D Maetzel, R Singh, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 267 | 2016 |
| Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases M Renna, M Jimenez-Sanchez, S Sarkar, DC Rubinsztein Journal of Biological Chemistry 285 (15), 11061-11067, 2010 | 257 | 2010 |
| Mammalian macroautophagy at a glance B Ravikumar, M Futter, L Jahreiss, VI Korolchuk, M Lichtenberg, S Luo, ... Journal of Cell Science 122 (11), 1707-1711, 2009 | 256 | 2009 |
David RubinszteinUniversity of CambridgeVerified email at cam.ac.uk
