| Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila JS Steffan, L Bodai, J Pallos, M Poelman, A McCampbell, BL Apostol, ... Nature 413 (6857), 739-743, 2001 | 1485 | 2001 |
| Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease E Hockly, VM Richon, B Woodman, DL Smith, X Zhou, E Rosa, ... Proceedings of the National Academy of Sciences 100 (4), 2041-2046, 2003 | 1064 | 2003 |
| SUMO modification of Huntingtin and Huntington's disease pathology JS Steffan, N Agrawal, J Pallos, E Rockabrand, LC Trotman, N Slepko, ... Science 304 (5667), 100-104, 2004 | 911 | 2004 |
| The pIC plasmid and phage vectors with versatile cloning sites for recombinant selection by insertional inactivation JL Marsh, M Erfle, EJ Wykes Gene 32 (3), 481-485, 1984 | 819 | 1984 |
| β-catenin–sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer K Hovanes, TWH Li, JE Munguia, T Truong, T Milovanovic, ... Nature genetics 28 (1), 53-57, 2001 | 631 | 2001 |
| Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models DE Ehrnhoefer, M Duennwald, P Markovic, JL Wacker, S Engemann, ... Human molecular genetics 15 (18), 2743-2751, 2006 | 495 | 2006 |
| IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome LM Thompson, CT Aiken, LS Kaltenbach, N Agrawal, K Illes, A Khoshnan, ... Journal of Cell Biology 187 (7), 1083-1099, 2009 | 455 | 2009 |
| SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis R Luthi-Carter, DM Taylor, J Pallos, E Lambert, A Amore, A Parker, ... Proceedings of the National Academy of Sciences 107 (17), 7927-7932, 2010 | 400 | 2010 |
| Twisted gastrulation is a conserved extracellular BMP antagonist JJ Ross, O Shimmi, P Vilmos, A Petryk, H Kim, K Gaudenz, S Hermanson, ... Nature 410 (6827), 479-483, 2001 | 369 | 2001 |
| The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis E Rockabrand, N Slepko, A Pantalone, VN Nukala, A Kazantsev, ... Human molecular genetics 16 (1), 61-77, 2007 | 338 | 2007 |
| A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo X Zhang, DL Smith, AB Meriin, S Engemann, DE Russel, M Roark, ... Proceedings of the national academy of sciences 102 (3), 892-897, 2005 | 329 | 2005 |
| Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease J Pallos, L Bodai, T Lukacsovich, JM Purcell, JS Steffan, LM Thompson, ... Human molecular genetics 17 (23), 3767-3775, 2008 | 326 | 2008 |
| Potential function for the Huntingtin protein as a scaffold for selective autophagy J Ochaba, T Lukacsovich, G Csikos, S Zheng, J Margulis, L Salazar, ... Proceedings of the National Academy of Sciences 111 (47), 16889-16894, 2014 | 315 | 2014 |
| Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila JL Marsh, H Walker, H Theisen, YZ Zhu, T Fielder, J Purcell, ... Human molecular genetics 9 (1), 13-25, 2000 | 311 | 2000 |
| The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development KG Johnson, AP Tenney, A Ghose, AM Duckworth, ME Higashi, K Parfitt, ... Neuron 49 (4), 517-531, 2006 | 284 | 2006 |
| dishevelled is required during wingless signaling to establish both cell polarity and cell identity H Theisen, J Purcell, M Bennett, D Kansagara, A Syed, JL Marsh Development 120 (2), 347-360, 1994 | 277 | 1994 |
| ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease P Maher, R Dargusch, L Bodai, PE Gerard, JM Purcell, JL Marsh Human molecular genetics 20 (2), 261-270, 2011 | 269 | 2011 |
| Drosophila in the study of neurodegenerative disease JL Marsh, LM Thompson Neuron 52 (1), 169-178, 2006 | 251 | 2006 |
| Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila TE Haerry, TR Heslip, JL Marsh, MB O’Connor Development 124 (16), 3055-3064, 1997 | 248 | 1997 |
| Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma RF Holcombe, JL Marsh, ML Waterman, F Lin, T Milovanovic, T Truong Molecular Pathology 55 (4), 220, 2002 | 230 | 2002 |
