| Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis L van Bon, AJ Affandi, J Broen, RB Christmann, RJ Marijnissen, L Stawski, ... New England Journal of Medicine 370 (5), 433-443, 2014 | 488 | 2014 |
| Interferon and alternative activation of monocyte/macrophages in systemic sclerosis–associated pulmonary arterial hypertension RB Christmann, E Hayes, S Pendergrass, C Padilla, G Farina, AJ Affandi, ... Arthritis & Rheumatology 63 (6), 1718-1728, 2011 | 149 | 2011 |
| CD169+ macrophages capture and dendritic cells instruct: the interplay of the gatekeeper and the general of the immune system J Grabowska, MA Lopez-Venegas, AJ Affandi, JMM Den Haan Frontiers in Immunology 9, 2018 | 129 | 2018 |
| Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis G Stifano, AJ Affandi, AL Mathes, LM Rice, S Nakerakanti, B Nazari, J Lee, ... Arthritis research & therapy 16 (4), R136, 2014 | 96 | 2014 |
| Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosis E Chouri, NH Servaas, CPJ Bekker, AJ Affandi, M Cossu, MR Hillen, ... Journal of Autoimmunity, 2018 | 85 | 2018 |
| Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin AL Mathes, RB Christmann, G Stifano, AJ Affandi, TRDJ Radstake, ... Annals of the rheumatic diseases, annrheumdis-2012-202814, 2013 | 74 | 2013 |
| Update on biomarkers in systemic sclerosis: tools for diagnosis and treatment AJ Affandi, TRDJ Radstake, W Marut Seminars in immunopathology 37 (5), 475-487, 2015 | 73 | 2015 |
| Association of MicroRNA-618 Expression With Altered Frequency and Activation of Plasmacytoid Dendritic Cells in Patients With Systemic Sclerosis. M Rossato, AJ Affandi, S Thordardottir, CGK Wichers, M Cossu, ... Arthritis & rheumatology (Hoboken, NJ) 69 (9), 1891-1902, 2017 | 71 | 2017 |
| Thymic Stromal Lymphopoietin Is Up‐Regulated in the Skin of Patients With Systemic Sclerosis and Induces Profibrotic Genes and Intracellular Signaling That Overlap With Those … RB Christmann, A Mathes, AJ Affandi, C Padilla, B Nazari, AM Bujor, ... Arthritis & Rheumatology 65 (5), 1335-1346, 2013 | 71 | 2013 |
| Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes AJ Affandi, J Grabowska, K Olesek, ML Venegas, A Barbaria, E Rodríguez, ... Proceedings of the National Academy of Sciences 117 (44), 27528-27539, 2020 | 70 | 2020 |
| CXCL4 drives fibrosis by promoting several key cellular and molecular processes AJ Affandi, T Carvalheiro, A Ottria, JJ de Haan, MAD Brans, MM Brandt, ... Cell reports 38 (1), 2022 | 54 | 2022 |
| Cytometry by time of flight identifies distinct signatures in patients with systemic sclerosis, systemic lupus erythematosus and Sjögrens syndrome M van der Kroef, LL van den Hoogen, JS Mertens, SLM Blokland, ... European journal of immunology 50 (1), 119-129, 2020 | 53 | 2020 |
| Histone modifications underlie monocyte dysregulation in patients with systemic sclerosis, underlining the treatment potential of epigenetic targeting M van der Kroef, M Castellucci, M Mokry, M Cossu, M Garonzi, ... Annals of the rheumatic diseases 78 (4), 529-538, 2019 | 52 | 2019 |
| CXCL4 Exposure Potentiates TLR-Driven Polarization of Human Monocyte-Derived Dendritic Cells and Increases Stimulation of T Cells SC Silva-Cardoso, AJ Affandi, L Spel, M Cossu, JAG van Roon, M Boes, ... The Journal of Immunology 199 (1), 253-262, 2017 | 52 | 2017 |
| CD169 Defines Activated CD14+ Monocytes With Enhanced CD8+ T Cell Activation Capacity AJ Affandi, K Olesek, J Grabowska, MK Nijen Twilhaar, E Rodríguez, ... Frontiers in immunology 12, 697840, 2021 | 51 | 2021 |
| CXCL4 is a novel inducer of human Th17 cells and correlates with IL‐17 and IL‐22 in psoriatic arthritis AJ Affandi, SC Silva‐Cardoso, S Garcia, EFA Leijten, TS Kempen, ... European journal of immunology 48 (3), 522-531, 2018 | 47 | 2018 |
| Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis AJ Affandi, T Carvalheiro, A Ottria, JCA Broen, L Bossini-Castillo, ... Annals of the rheumatic diseases, annrheumdis-2018-214991, 2019 | 35 | 2019 |
| Dendritic cells in systemic sclerosis: advances from human and mice studies AJ Affandi, T Carvalheiro, TRDJ Radstake, W Marut Immunology Letters, 2017 | 35 | 2017 |
| Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4+ and CD8+ T-cell clusters in systemic sclerosis NH Servaas, F Zaaraoui-Boutahar, CGK Wichers, A Ottria, E Chouri, ... Journal of Autoimmunity 117, 102574, 2021 | 32 | 2021 |
| Liposome induction of CD8+ T cell responses depends on CD169+ macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion J Grabowska, AJ Affandi, D van Dinther, MKN Twilhaar, K Olesek, ... Journal of controlled release 331, 309-320, 2021 | 25 | 2021 |
Timothy RadstakeHead Early Immunology Discovery Research, AbbvieVerified email at abbvie.com