CTCF/cohesin-binding sites are frequently mutated in cancer R Katainen, K Dave, E Pitkänen, K Palin, T Kivioja, N Välimäki, AE Gylfe, ... Nature genetics 47 (7), 818-821, 2015 | 483 | 2015 |
Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer T Cajuso, UA Hänninen, J Kondelin, AE Gylfe, T Tanskanen, R Katainen, ... International journal of cancer 135 (3), 611-623, 2014 | 130 | 2014 |
Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis S May-Wilson, A Sud, PJ Law, K Palin, S Tuupanen, A Gylfe, ... European Journal of Cancer 84, 228-238, 2017 | 110 | 2017 |
Eleven candidate susceptibility genes for common familial colorectal cancer AE Gylfe, R Katainen, J Kondelin, T Tanskanen, T Cajuso, U Hänninen, ... PLoS genetics 9 (10), e1003876, 2013 | 102 | 2013 |
Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer H Rodriguez‐Broadbent, PJ Law, A Sud, K Palin, S Tuupanen, A Gylfe, ... International journal of cancer 140 (12), 2701-2708, 2017 | 93 | 2017 |
Identification of 33 candidate oncogenes by screening for base-specific mutations S Tuupanen, UA Hänninen, J Kondelin, P Von Nandelstadh, T Cajuso, ... British journal of cancer 111 (8), 1657-1662, 2014 | 82 | 2014 |
Identification of candidate oncogenes in human colorectal cancers with microsatellite instability AE Gylfe, J Kondelin, M Turunen, H Ristolainen, R Katainen, E Pitkänen, ... Gastroenterology 145 (3), 540-543. e22, 2013 | 81 | 2013 |
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer D Jarvis, JS Mitchell, PJ Law, K Palin, S Tuupanen, A Gylfe, UA Hänninen, ... British journal of cancer 115 (2), 266-272, 2016 | 80 | 2016 |
A Finnish founder mutation in RAD51D: analysis in breast, ovarian, prostate, and colorectal cancer LM Pelttari, J Kiiski, R Nurminen, A Kallioniemi, J Schleutker, A Gylfe, ... Journal of medical genetics 49 (7), 429-432, 2012 | 66 | 2012 |
Somatic mutations and germline sequence variants in patients with familial colorectal cancer AE Gylfe, J Sirkiä, M Ahlsten, H Järvinen, JP Mecklin, A Karhu, ... International journal of cancer 127 (12), 2974-2980, 2010 | 61 | 2010 |
Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease G Orlando, PJ Law, K Palin, S Tuupanen, A Gylfe, UA Hänninen, T Cajuso, ... Human molecular genetics 25 (11), 2349-2359, 2016 | 55 | 2016 |
Systematic search for rare variants in Finnish early-onset colorectal cancer patients T Tanskanen, AE Gylfe, R Katainen, M Taipale, L Renkonen-Sinisalo, ... Cancer genetics 208 (1-2), 35-40, 2015 | 39 | 2015 |
Genome‐wide association study and meta‐analysis in Northern European populations replicate multiple colorectal cancer risk loci T Tanskanen, L Van Den Berg, N Välimäki, M Aavikko, E Ness‐Jensen, ... International Journal of Cancer 142 (3), 540-546, 2018 | 32 | 2018 |
Comprehensive evaluation of protein coding mononucleotide microsatellites in microsatellite-unstable colorectal cancer J Kondelin, AE Gylfe, S Lundgren, T Tanskanen, J Hamberg, M Aavikko, ... Cancer Research 77 (15), 4078-4088, 2017 | 28 | 2017 |
Characterization of the colorectal cancer–associated enhancer MYC-335 at 8q24: the role of rs67491583 S Tuupanen, J Yan, M Turunen, AE Gylfe, E Kaasinen, L Li, C Eng, ... Cancer genetics 205 (1-2), 25-33, 2012 | 28 | 2012 |
Exome sequencing in diagnostic evaluation of colorectal cancer predisposition in young patients T Tanskanen, AE Gylfe, R Katainen, M Taipale, L Renkonen-Sinisalo, ... Scandinavian journal of gastroenterology 48 (6), 672-678, 2013 | 21 | 2013 |
High frequency of TTK mutations in microsatellite-unstable colorectal cancer and evaluation of their effect on spindle assembly checkpoint I Niittymäki, A Gylfe, L Laine, M Laakso, HJ Lehtonen, J Kondelin, ... Carcinogenesis 32 (3), 305-311, 2011 | 17 | 2011 |
Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer J Kondelin, K Salokas, L Saarinen, K Ovaska, H Rauanheimo, RM Plaketti, ... EMBO molecular medicine 10 (9), e8552, 2018 | 16 | 2018 |
Screening of Finnish RAD51Cfounder mutations in prostate and colorectal cancer patients LM Pelttari, R Nurminen, A Gylfe, LA Aaltonen, J Schleutker, ... BMC cancer 12, 1-4, 2012 | 14 | 2012 |
3′-UTR poly(T/U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer with nearly perfect sensitivity J Kondelin, S Tuupanen, AE Gylfe, M Aavikko, L Renkonen-Sinisalo, ... Familial cancer 14, 449-453, 2015 | 3 | 2015 |