MicroRNAs: control and loss of control in human physiology and disease M Li, C Marin-Muller, U Bharadwaj, KH Chow, Q Yao, C Chen World journal of surgery 33, 667-684, 2009 | 326 | 2009 |
Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression M Li, Y Zhang, Z Liu, U Bharadwaj, H Wang, X Wang, S Zhang, JP Liuzzi, ... Proceedings of the National Academy of Sciences 104 (47), 18636-18641, 2007 | 303 | 2007 |
Targeting janus kinases and signal transducer and activator of transcription 3 to treat inflammation, fibrosis, and cancer: rationale, progress, and caution U Bharadwaj, MM Kasembeli, P Robinson, DJ Tweardy, DY Richard Pharmacological reviews 72 (2), 486-526, 2020 | 253 | 2020 |
RETRACTED: Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in … BB Aggarwal, S Banerjee, U Bharadwaj, B Sung, S Shishodia, G Sethi Biochemical pharmacology 73 (7), 1024-1032, 2007 | 218 | 2007 |
Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147 M Li, Q Zhai, U Bharadwaj, H Wang, F Li, WE Fisher, C Chen, Q Yao Cancer 106 (10), 2284-2294, 2006 | 213 | 2006 |
Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer M Li, U Bharadwaj, R Zhang, S Zhang, H Mu, WE Fisher, FC Brunicardi, ... Molecular cancer therapeutics 7 (2), 286-296, 2008 | 193 | 2008 |
Elevated interleukin-6 and G-CSF in human pancreatic cancer cell conditioned medium suppress dendritic cell differentiation and activation U Bharadwaj, M Li, R Zhang, C Chen, Q Yao Cancer research 67 (11), 5479-5488, 2007 | 185 | 2007 |
Contribution of STAT3 to inflammatory and fibrotic diseases and prospects for its targeting for treatment MM Kasembeli, U Bharadwaj, P Robinson, DJ Tweardy International journal of molecular sciences 19 (8), 2299, 2018 | 174 | 2018 |
Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer U Bharadwaj, TK Eckols, M Kolosov, MM Kasembeli, A Adam, D Torres, ... Oncogene 34 (11), 1341-1353, 2015 | 170 | 2015 |
Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression U Bharadwaj, C Marin-Muller, M Li, C Chen, Q Yao Molecular cancer 10, 1-14, 2011 | 158 | 2011 |
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy M Sharma, H Khong, F Fa’ak, SE Bentebibel, LME Janssen, BC Chesson, ... Nature communications 11 (1), 661, 2020 | 157 | 2020 |
Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans MK Lay, RL Atmar, S Guix, U Bharadwaj, H He, FH Neill, KJ Sastry, Q Yao, ... Virology 406 (1), 1-11, 2010 | 133 | 2010 |
ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB Y Zhang, U Bharadwaj, CD Logsdon, C Chen, Q Yao, M Li Clinical Cancer Research 16 (5), 1423-1430, 2010 | 130 | 2010 |
IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells LW Feurino, Y Zhang, U Bharadwaj, R Zhang, F Li, WE Fisher, ... Cancer biology & therapy 6 (7), 1096-1100, 2007 | 130 | 2007 |
Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation U Bharadwaj, C Marin-Muller, M Li, C Chen, Q Yao Carcinogenesis 32 (7), 1013-1024, 2011 | 124 | 2011 |
Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts M Li, Y Zhang, U Bharadwaj, Q Zhai, CH Ahern, WE Fisher, FC Brunicardi, ... Clinical Cancer Research 15 (19), 5993-6001, 2009 | 120 | 2009 |
Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells C Chen, H Chai, X Wang, J Jiang, MS Jamaluddin, D Liao, Y Zhang, ... Blood, The Journal of the American Society of Hematology 112 (8), 3205-3216, 2008 | 118 | 2008 |
Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3 U Bharadwaj, M Li, C Chen, Q Yao Molecular Cancer Research 6 (11), 1755-1765, 2008 | 117 | 2008 |
Multifunctional effects of a small-molecule STAT3 inhibitor on NASH and hepatocellular carcinoma in mice KH Jung, W Yoo, HL Stevenson, D Deshpande, H Shen, M Gagea, ... Clinical Cancer Research 23 (18), 5537-5546, 2017 | 112 | 2017 |
STAT3 inhibition prevents lung inflammation, remodeling, and accumulation of Th2 and Th17 cells in a murine asthma model AC Gavino, K Nahmod, U Bharadwaj, G Makedonas, DJ Tweardy Allergy 71 (12), 1684-1692, 2016 | 106 | 2016 |