A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity RM Marión, K Strati, H Li, M Murga, R Blanco, S Ortega, ... Nature 460 (7259), 1149-1153, 2009 | 1239 | 2009 |
The Ink4/Arf locus is a barrier for iPS cell reprogramming H Li, M Collado, A Villasante, K Strati, S Ortega, M Cañamero, MA Blasco, ... Nature 460 (7259), 1136-1139, 2009 | 1146 | 2009 |
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells RM Marion, K Strati, H Li, A Tejera, S Schoeftner, S Ortega, M Serrano, ... Cell stem cell 4 (2), 141-154, 2009 | 615 | 2009 |
Injury-induced senescence enables in vivo reprogramming in skeletal muscle A Chiche, I Le Roux, M von Joest, H Sakai, SB Aguín, C Cazin, R Salam, ... Cell stem cell 20 (3), 407-414. e4, 2017 | 299 | 2017 |
p27Kip1 directly represses Sox2 during embryonic stem cell differentiation H Li, M Collado, A Villasante, A Matheu, CJ Lynch, M Cañamero, ... Cell stem cell 11 (6), 845-852, 2012 | 198 | 2012 |
Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer H Li, H Vogel, VB Holcomb, Y Gu, P Hasty Molecular and cellular biology 27 (23), 8205-8214, 2007 | 165 | 2007 |
SUMO safeguards somatic and pluripotent cell identities by enforcing distinct chromatin states JC Cossec, I Theurillat, C Chica, SB Aguín, X Gaume, A Andrieux, ... Cell stem cell 23 (5), 742-757. e8, 2018 | 126 | 2018 |
Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells S Ruiz, AJ Lopez-Contreras, M Gabut, RM Marion, P Gutierrez-Martinez, ... Nature communications 6 (1), 8036, 2015 | 109 | 2015 |
DNA double-strand breaks: a potential causative factor for mammalian aging? H Li, JR Mitchell, P Hasty Mechanisms of ageing and development 129 (7-8), 416-424, 2008 | 88 | 2008 |
Primary mammary organoid model of lactation and involution J Sumbal, A Chiche, E Charifou, Z Koledova, H Li Frontiers in cell and developmental biology 8, 68, 2020 | 72 | 2020 |
Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells I Horikawa, K Park, K Isogaya, Y Hiyoshi, H Li, K Anami, AI Robles, ... Cell Death & Differentiation 24 (6), 1017-1028, 2017 | 72 | 2017 |
Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency S Menendez, S Camus, A Herreria, I Paramonov, LB Morera, M Collado, ... Aging cell 11 (1), 41-50, 2012 | 63 | 2012 |
Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells A Villasante, D Piazzolla, H Li, G Gomez-Lopez, M Djabali, M Serrano Cell Cycle 10 (9), 1488-1498, 2011 | 60 | 2011 |
Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer AR Palla, D Piazzolla, M Abad, H Li, O Dominguez, HB Schonthaler, ... Oncogene 33 (19), 2513-2519, 2014 | 58 | 2014 |
SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53 CJ Lynch, ZH Shah, SJ Allison, SU Ahmed, J Ford, LJ Warnock, H Li, ... PloS one 5 (10), e13502, 2010 | 57 | 2010 |
Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor M Yaneva, H Li, T Marple, P Hasty Nucleic acids research 33 (16), 5320-5330, 2005 | 47 | 2005 |
Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction‐like phenotype in aged mice L Katsimpardi, N Kuperwasser, C Camus, C Moigneu, A Chiche, V Tolle, ... Aging Cell 19 (1), e13038, 2020 | 41 | 2020 |
A genotoxic screen: rapid analysis of cellular dose–response to a wide range of agents that either damage DNA or alter genome maintenance pathways T Marple, H Li, P Hasty Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 554 (1 …, 2004 | 32 | 2004 |
Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair YJ Choi, H Li, MY Son, X Wang, JL Fornsaglio, RW Sobol, M Lee, J Vijg, ... PloS one 9 (1), e86358, 2014 | 30 | 2014 |
Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells H Li, YJ Choi, MA Hanes, T Marple, H Vogel, P Hasty Oncogene 28 (16), 1875-1878, 2009 | 26 | 2009 |