Mechanotransduction pathways linking the extracellular matrix to the nucleus Z Jahed, H Shams, M Mehrbod, MRK Mofrad International review of cell and molecular biology 310, 171-220, 2014 | 147 | 2014 |
Locus for severity implicates CNS resilience in progression of multiple sclerosis MultipleMS Consortium Harroud Adil 1 78 78 Jónsdóttir Ingileif 74 75 Blanco ... Nature 619 (7969), 323-331, 2023 | 95 | 2023 |
Actin reorganization through dynamic interactions with single-wall carbon nanotubes H Shams, BD Holt, SH Mahboobi, Z Jahed, MF Islam, KN Dahl, ... ACS nano 8 (1), 188-197, 2014 | 52 | 2014 |
Kindlin assists talin to promote integrin activation Z Haydari, H Shams, Z Jahed, MRK Mofrad Biophysical journal 118 (8), 1977-1991, 2020 | 45 | 2020 |
A molecular trajectory of α-actinin activation H Shams, J Golji, MRK Mofrad Biophysical journal 103 (10), 2050-2059, 2012 | 44 | 2012 |
Altered cell mechanics from the inside: dispersed single wall carbon nanotubes integrate with and restructure actin BD Holt, H Shams, TA Horst, S Basu, AD Rape, YL Wang, GK Rohde, ... Journal of functional biomaterials 3 (2), 398-417, 2012 | 44 | 2012 |
Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans H Shams, X Shao, A Santaniello, G Kirkish, A Harroud, Q Ma, N Isobe, ... Brain 146 (2), 645-656, 2023 | 43 | 2023 |
A disulfide bond is required for the transmission of forces through SUN-KASH complexes Z Jahed, H Shams, MRK Mofrad Biophysical Journal 109 (3), 501-509, 2015 | 42 | 2015 |
Dynamic regulation of α-actinin’s calponin homology domains on F-actin H Shams, J Golji, K Garakani, MRK Mofrad Biophysical journal 110 (6), 1444-1455, 2016 | 37 | 2016 |
High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity LM Amorim, DG Augusto, N Nemat-Gorgani, G Montero-Martin, WM Marin, ... Frontiers in Immunology 12, 674778, 2021 | 31 | 2021 |
Mechanisms of integrin and filamin binding and their interplay with talin during early focal adhesion formation T Truong, H Shams, MRK Mofrad Integrative Biology 7 (10), 1285-1296, 2015 | 31 | 2015 |
Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis A Didonna, E Canto Puig, Q Ma, A Matsunaga, B Ho, SJ Caillier, H Shams, ... Proceedings of the National Academy of Sciences 117 (38), 23742-23750, 2020 | 22 | 2020 |
Looking “under the Hood” of cellular Mechanotransduction with computational tools: a systems biomechanics approach across multiple scales H Shams, M Soheilypour, M Peyro, R Moussavi-Baygi, MRK Mofrad ACS biomaterials science & engineering 3 (11), 2712-2726, 2017 | 22 | 2017 |
Mechanosensitive conformation of vinculin regulates its binding to MAPK1 K Garakani, H Shams, MRK Mofrad Biophysical journal 112 (9), 1885-1893, 2017 | 22 | 2017 |
Killer cell immunoglobulin-like receptor variants are associated with protection from symptoms associated with more severe course in Parkinson disease KM Anderson, DG Augusto, R Dandekar, H Shams, C Zhao, T Yusufali, ... The Journal of Immunology 205 (5), 1323-1330, 2020 | 21 | 2020 |
Steric regulation of tandem calponin homology domain actin-binding affinity AR Harris, B Belardi, P Jreij, K Wei, H Shams, A Bausch, DA Fletcher Molecular biology of the cell 30 (26), 3112-3122, 2019 | 20 | 2019 |
Integration of epigenetic and genetic profiles identifies multiple sclerosis disease-critical cell types and genes Q Ma, H Shams, A Didonna, SE Baranzini, BAC Cree, SL Hauser, ... Communications biology 6 (1), 342, 2023 | 19 | 2023 |
Structural basis of the differential binding of engineered knottins to integrins αVβ3 and α5β1 JF Van Agthoven, H Shams, FV Cochran, JL Alonso, JR Kintzing, ... Structure 27 (9), 1443-1451. e6, 2019 | 18 | 2019 |
α-Actinin induces a kink in the transmembrane domain of β3-integrin and impairs activation via talin H Shams, MRK Mofrad Biophysical journal 113 (4), 948-956, 2017 | 18 | 2017 |
Enhanced intracellular delivery of small molecules and drugs via non-covalent ternary dispersions of single-wall carbon nanotubes PD Boyer, H Shams, SL Baker, MRK Mofrad, MF Islam, KN Dahl Journal of Materials Chemistry B 4 (7), 1324-1330, 2016 | 14 | 2016 |