A bacteriolytic agent that detects and kills Bacillus anthracis R Schuch, D Nelson, VA Fischetti Nature 418 (6900), 884-889, 2002 | 896 | 2002 |
Identification of a Broadly Active Phage Lytic Enzyme with Lethal Activity against Antibiotic-Resistant Enterococcus faecalis and Enterococcus faecium P Yoong, R Schuch, D Nelson, VA Fischetti Journal of bacteriology 186 (14), 4808-4812, 2004 | 347 | 2004 |
Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model R Lood, BY Winer, AJ Pelzek, R Diez-Martinez, M Thandar, CW Euler, ... Antimicrobial agents and chemotherapy 59 (4), 1983-1991, 2015 | 292 | 2015 |
PlyC: a multimeric bacteriophage lysin D Nelson, R Schuch, P Chahales, S Zhu, VA Fischetti Proceedings of the National Academy of Sciences 103 (28), 10765-10770, 2006 | 267 | 2006 |
Lysins: the arrival of pathogen-directed anti-infectives M Pastagia, R Schuch, VA Fischetti, DB Huang Journal of medical microbiology 62 (10), 1506-1516, 2013 | 256 | 2013 |
Reinventing phage therapy: are the parts greater than the sum? VA Fischetti, D Nelson, R Schuch Nature biotechnology 24 (12), 1508-1511, 2006 | 245 | 2006 |
Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine … R Schuch, HM Lee, BC Schneider, KL Sauve, C Law, BK Khan, JA Rotolo, ... The Journal of infectious diseases 209 (9), 1469-1478, 2014 | 225 | 2014 |
The secret life of the anthrax agent Bacillus anthracis: bacteriophage-mediated ecological adaptations R Schuch, VA Fischetti PloS one 4 (8), e6532, 2009 | 215 | 2009 |
Bacteriophage lysin CF-301, a potent antistaphylococcal biofilm agent R Schuch, BK Khan, A Raz, JA Rotolo, M Wittekind Antimicrobial agents and chemotherapy 61 (7), 10.1128/aac. 02666-16, 2017 | 171 | 2017 |
PlyPH, a Bacteriolytic Enzyme with a Broad pH Range of Activity and Lytic Action against Bacillus anthracis P Yoong, R Schuch, D Nelson, VA Fischetti Journal of bacteriology 188 (7), 2711-2714, 2006 | 127 | 2006 |
Detailed Genomic Analysis of the Wβ and γ Phages Infecting Bacillus anthracis: Implications for Evolution of Environmental Fitness and Antibiotic Resistance R Schuch, VA Fischetti Journal of bacteriology 188 (8), 3037-3051, 2006 | 124 | 2006 |
MxiE Regulates Intracellular Expression of Factors Secreted by the Shigella flexneri 2a Type III Secretion System CD Kane, R Schuch, WA Day Jr, AT Maurelli Journal of bacteriology 184 (16), 4409-4419, 2002 | 118 | 2002 |
The 1.6 Å Crystal Structure of the Catalytic Domain of PlyB, a Bacteriophage Lysin Active Against Bacillus anthracis CJ Porter, R Schuch, AJ Pelzek, AM Buckle, S McGowan, MCJ Wilce, ... Journal of molecular biology 366 (2), 540-550, 2007 | 116 | 2007 |
A system for identifying post‐invasion functions of invasion genes: requirements for the Mxi–Spa type III secretion pathway of Shigella flexneri in intercellular … R Schuch, RC Sandlin, AT Maurelli Molecular microbiology 34 (4), 675-689, 1999 | 111 | 1999 |
Exebacase for patients with Staphylococcus aureus bloodstream infection and endocarditis VG Fowler, AF Das, J Lipka-Diamond, R Schuch, R Pomerantz, ... The Journal of clinical investigation 130 (7), 3750-3760, 2020 | 109 | 2020 |
MxiM and MxiJ, Base Elements of the Mxi-Spa Type III Secretion System of Shigella, Interact with and Stabilize the MxiD Secretin in the Cell Envelope R Schuch, AT Maurelli Journal of bacteriology 183 (24), 6991-6998, 2001 | 99 | 2001 |
Lysocins: bioengineered antimicrobials that deliver lysins across the outer membrane of Gram-negative bacteria RD Heselpoth, CW Euler, R Schuch, VA Fischetti Antimicrobial Agents and Chemotherapy 63 (6), 10.1128/aac. 00342-19, 2019 | 95 | 2019 |
Development of a high throughput assay for indirectly measuring phage growth using the OmniLogTM system M Henry, B Biswas, L Vincent, V Mokashi, R Schuch, KA Bishop-Lilly, ... Bacteriophage 2 (3), 159-167, 2012 | 90 | 2012 |
nadA and nadB of Shigella flexneri 5a are antivirulence loci responsible for the synthesis of quinolinate, a small molecule inhibitor of Shigella pathogenicity AL Prunier, R Schuch, RE Fernandez, KL Mumy, H Kohler, BA McCormick, ... Microbiology 153 (7), 2363-2372, 2007 | 80 | 2007 |
Characterization of a Bacillus subtilis sporulation operon that includes genes for an RNA polymerase sigma factor and for a putative DD-carboxypeptidase JJ Wu, R Schuch, PJ Piggot Journal of bacteriology 174 (15), 4885-4892, 1992 | 79 | 1992 |