The DNA Repair Nuclease MRE11A Functions as a Mitochondrial Protector and Prevents T Cell Pyroptosis and Tissue Inflammation Y Li, Y Shen, K Jin, Z Wen, W Cao, B Wu, R Wen, L Tian, GJ Berry, ... Cell metabolism 30 (3), 477-492. e6, 2019 | 148 | 2019 |
N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation Z Wen, K Jin, Y Shen, Z Yang, Y Li, B Wu, L Tian, S Shoor, NE Roche, ... Nature immunology 20 (3), 313, 2019 | 131 | 2019 |
Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma Z Wang, TG Da Silva, K Jin, X Han, P Ranganathan, X Zhu, ... Cancer research 74 (21), 6364-6374, 2014 | 103 | 2014 |
Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation B Wu, TV Zhao, K Jin, Z Hu, MP Abdel, KJ Warrington, JJ Goronzy, ... Nature immunology 22 (12), 1551-1562, 2021 | 80 | 2021 |
The small molecule IMR-1 inhibits the notch transcriptional activation complex to suppress tumorigenesis L Astudillo, TG Da Silva, Z Wang, X Han, K Jin, J VanWye, X Zhu, ... Cancer research 76 (12), 3593-3603, 2016 | 77 | 2016 |
Succinyl-CoA ligase deficiency in pro-inflammatory and tissue-invasive T cells B Wu, J Qiu, TV Zhao, Y Wang, T Maeda, IN Goronzy, M Akiyama, ... Cell Metabolism 32 (6), 967-980. e5, 2020 | 72 | 2020 |
NOTCH-induced rerouting of endosomal trafficking disables regulatory T-cells in vasculitis K Jin, Z Wen, B Wu, H Zhang, J Qiu, Y Wang, KJ Warrington, G Berry, ... The Journal of Clinical Investigation, 2020 | 59 | 2020 |
NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis KL Weaver, MC Alves-Guerra, K Jin, Z Wang, X Han, P Ranganathan, ... Cancer research 74 (17), 4741-4751, 2014 | 42 | 2014 |
Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors B Li, D Orton, LR Neitzel, L Astudillo, C Shen, J Long, X Chen, ... Sci. Signal. 10 (485), eaak9916, 2017 | 41 | 2017 |
Acetylation of mastermind-like 1 by p300 drives the recruitment of NACK to initiate notch-dependent transcription K Jin, W Zhou, X Han, Z Wang, B Li, S Jeffries, W Tao, DJ Robbins, ... Cancer research 77 (16), 4228-4237, 2017 | 30 | 2017 |
Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma DW Sant, W Tao, MG Field, D Pelaez, K Jin, A Capobianco, SR Dubovy, ... Investigative ophthalmology & visual science 58 (6), BIO240-BIO246, 2017 | 25 | 2017 |
Regulatory T cells in Autoimmune Vasculitis K Jin, S Parreau, K Warrington, M Koster, G Berry, J Goronzy, C Weyand Frontiers in Immunology 13, 2022 | 22 | 2022 |
Notch represses transcription by PRC2 recruitment to the ternary complex X Han, P Ranganathan, C Tzimas, KL Weaver, K Jin, L Astudillo, W Zhou, ... Molecular Cancer Research 15 (9), 1173-1183, 2017 | 19 | 2017 |
Arsenic attenuates GLI signaling, increasing or decreasing its transcriptional program in a context-dependent manner B Li, C Giambelli, B Tang, E Winterbottom, J Long, K Jin, Z Wang, DL Fei, ... Molecular pharmacology 89 (2), 226-232, 2016 | 10 | 2016 |
Adenoid Cystic Carcinoma of the Lacrimal Gland: Clinical, Genetic and Molecular Characteristics S Pappas, K Jin, CT Brian, TT David, D Pelaez, W Tao Molecular Oncology: Underlying Mechanisms and Translational Advancements …, 2017 | 1 | 2017 |
Sebaceous Carcinoma of the Eyelid AL Garcia, K Jin, R Doddapaneni, CJ Choi, MP Fernandez, S Dubovy, ... Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and …, 2018 | | 2018 |
Abstract A33: Discovery of novel anti-cancer therapeutic agents for Notch activation complex kinase (NACK) targeting the Notch pathway X Zhu, Z Wang, K Jin, L Astudillo, W Zhou, J Chen, P Buchwald, ... Clinical Cancer Research 23 (1 Supplement), A33-A33, 2017 | | 2017 |