CAR T cell therapy for solid tumors: bright future or dark reality? J Wagner, E Wickman, C DeRenzo, S Gottschalk Molecular therapy 28 (11), 2320-2339, 2020 | 307 | 2020 |
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity B Prinzing, CC Zebley, CT Petersen, Y Fan, AA Anido, Z Yi, P Nguyen, ... Science translational medicine 13 (620), eabh0272, 2021 | 218 | 2021 |
Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma M Hegde, SK Joseph, F Pashankar, C DeRenzo, K Sanber, S Navai, ... Nature communications 11 (1), 3549, 2020 | 142 | 2020 |
cBAF complex components and MYC cooperate early in CD8+ T cell fate A Guo, H Huang, Z Zhu, MJ Chen, H Shi, S Yuan, P Sharma, JP Connelly, ... Nature 607 (7917), 135-141, 2022 | 122 | 2022 |
Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery D Haydar, H Houke, J Chiang, Z Yi, Z Odé, K Caldwell, X Zhu, KS Mercer, ... Neuro-oncology 23 (6), 999-1011, 2021 | 96 | 2021 |
Genetic modification strategies to enhance CAR T cell persistence for patients with solid tumors C DeRenzo, S Gottschalk Frontiers in Immunology 10, 218, 2019 | 58 | 2019 |
Route of 41BB/41BBL costimulation determines effector function of B7-H3-CAR. CD28ζ T cells P Nguyen, E Okeke, M Clay, D Haydar, J Justice, C O’Reilly, ... Molecular Therapy-Oncolytics 18, 202-214, 2020 | 54 | 2020 |
Abstract LB-147: Administration of HER2-CAR T cells after lymphodepletion safely improves T cell expansion and induces clinical responses in patients with advanced sarcomas SA Navai, C Derenzo, S Joseph, K Sanber, T Byrd, H Zhang, M Mata, ... Cancer Research 79 (13_Supplement), LB-147-LB-147, 2019 | 51 | 2019 |
Autoshaping of ethanol drinking: an animal model of binge drinking A Tomie, J Di Poce, CC Derenzo, LA Pohorecky Alcohol and Alcoholism 37 (2), 138-146, 2002 | 48 | 2002 |
Expansion of HER2-CAR T cells after lymphodepletion and clinical responses in patients with advanced sarcoma. M Hegde, CC DeRenzo, H Zhang, M Mata, C Gerken, A Shree, Z Yi, ... Journal of Clinical Oncology 35 (15_suppl), 10508-10508, 2017 | 47 | 2017 |
The Landscape of CAR T cells beyond ALL for Pediatric Solid Tumors C DeRenzo, G Krenciute, S Gottschalk American Society of Clinical Oncology educational book. American Society of …, 2018 | 34 | 2018 |
P53 regulates the migration of mesenchymal stromal cells in response to the tumor microenvironment through both CXCL12-dependent and-independent mechanisms SY Lin, SC Dolfi, S Amiri, J Li, T Budak-Alpdogan, KC Lee, C Derenzo, ... International Journal of Oncology 43 (6), 1817-1823, 2013 | 30 | 2013 |
A novel orthotopic implantation technique for osteosarcoma produces spontaneous metastases and illustrates dose-dependent efficacy of B7-H3-CAR T cells LJ Talbot, A Chabot, A Funk, P Nguyen, J Wagner, A Ross, H Tillman, ... Frontiers in Immunology 12, 691741, 2021 | 29 | 2021 |
Genetically modified T cells to target glioblastoma S Krebs, TG Rodríguez-Cruz, C DeRenzo, S Gottschalk Frontiers in oncology 3, 322, 2013 | 28 | 2013 |
A costimulatory CAR improves TCR-based cancer immunotherapy B Omer, MG Cardenas, T Pfeiffer, R Daum, M Huynh, S Sharma, ... Cancer immunology research 10 (4), 512-524, 2022 | 25 | 2022 |
Genetically modified T-cell therapy for osteosarcoma C DeRenzo, S Gottschalk Current Advances in Osteosarcoma, 323-340, 2014 | 22 | 2014 |
Nonoperative management of abdominoscrotal hydroceles in an infant CC De Renzo, JG Barone Urology 68 (2), 428. e9-428. e11, 2006 | 22 | 2006 |
CD47 expression is critical for CAR T-cell survival in vivo AN Beckett, P Chockley, SM Pruett-Miller, P Nguyen, P Vogel, ... Journal for ImmunoTherapy of Cancer 11 (3), 2023 | 19 | 2023 |
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial M Hegde, S Navai, C DeRenzo, SK Joseph, K Sanber, M Wu, AZ Gad, ... Nature cancer, 1-15, 2024 | 16 | 2024 |
Salvage regimens for pediatric patients with relapsed nasopharyngeal carcinoma C DeRenzo, C Lam, C Rodriguez‐Galindo, L Rapkin, S Gottschalk, ... Pediatric blood & cancer 66 (1), e27469, 2019 | 15 | 2019 |