| Single-cell transcriptomic analysis of mouse neocortical development L Loo, JM Simon, L Xing, ES McCoy, JK Niehaus, J Guo, ES Anton, ... Nature communications 10 (1), 134, 2019 | 283 | 2019 |
| Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction LP Sowers, L Loo, Y Wu, E Campbell, JD Ulrich, S Wu, L Paemka, ... Molecular psychiatry 18 (10), 1077-1089, 2013 | 111 | 2013 |
| scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy JK Ocasio, B Babcock, D Malawsky, SJ Weir, L Loo, JM Simon, MJ Zylka, ... Nature communications 10 (1), 5829, 2019 | 107 | 2019 |
| Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury JK Niehaus, B Taylor-Blake, L Loo, JM Simon, MJ Zylka Neuron 109 (8), 1274-1282. e6, 2021 | 97 | 2021 |
| The lipid kinase PIP5K1C regulates pain signaling and sensitization BD Wright, L Loo, SE Street, A Ma, B Taylor-Blake, MA Stashko, J Jin, ... Neuron 82 (4), 836-847, 2014 | 80 | 2014 |
| TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammation RY Walder, R Radhakrishnan, L Loo, LA Rasmussen, DP Mohapatra, ... PAIN® 153 (8), 1664-1672, 2012 | 68 | 2012 |
| Regulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling B Maity, A Stewart, J Yang, L Loo, D Sheff, AJ Shepherd, DP Mohapatra, ... Journal of Biological Chemistry 287 (7), 4972-4981, 2012 | 65 | 2012 |
| The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel L Loo, AJ Shepherd, AD Mickle, RA Lorca, LP Shutov, YM Usachev, ... Journal of Neuroscience 32 (35), 11942-11955, 2012 | 56 | 2012 |
| Distinct modifications in Kv2. 1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics AJ Shepherd, L Loo, RP Gupte, AD Mickle, DP Mohapatra Journal of Neuroscience 32 (49), 17725-17739, 2012 | 49 | 2012 |
| Induction of thermal and mechanical hypersensitivity by parathyroid hormone–related peptide through upregulation of Trpv1 function and trafficking AD Mickle, AJ Shepherd, L Loo, DP Mohapatra Pain 156 (9), 1620-1636, 2015 | 35 | 2015 |
| Vascular senescence and leak are features of the early breakdown of the blood–brain barrier in Alzheimer’s disease models KK Ting, P Coleman, HJ Kim, Y Zhao, J Mulangala, NC Cheng, W Li, ... Geroscience 45 (6), 3307-3331, 2023 | 32 | 2023 |
| Human induced pluripotent stem cell-derived GABAergic interneuron transplants attenuate neuropathic pain J Manion, T Khuong, D Harney, JB Littleboy, T Ruan, L Loo, M Costigan, ... Pain 161 (2), 379-387, 2020 | 31 | 2020 |
| Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs L Loo, MA Waller, CL Moreno, AJ Cole, AO Stella, OT Pop, AK Jochum, ... PLoS biology 21 (2), e3001967, 2023 | 30 | 2023 |
| Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2. 1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure AJ Shepherd, L Loo, DP Mohapatra PLoS One 8 (9), e76698, 2013 | 30 | 2013 |
| Single-cell transcriptomic analysis of mouse neocortical development. Nat. Commun. 10, 134 L Loo, JM Simon, L Xing, ES McCoy, JK Niehaus, J Guo, ES Anton, ... | 15 | 2019 |
| Peripheral straightjacket (α2δ Ca2+ channel subunit) expression is required for neuropathic sensitization in Drosophila TM Khuong, Z Hamoudi, J Manion, L Loo, A Muralidharan, GG Neely Philosophical Transactions of the Royal Society B 374 (1785), 20190287, 2019 | 13 | 2019 |
| Lipid kinases as therapeutic targets for chronic pain L Loo, BD Wright, MJ Zylka Pain 156, S2-S10, 2015 | 13 | 2015 |
| Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice L Xing, JM Simon, TS Ptacek, JY Jason, L Loo, H Mao, JM Wolter, ... Cell reports 42 (7), 2023 | 12 | 2023 |
| LRRC15 suppresses SARS-CoV-2 infection and controls collagen production L Loo, MA Waller, AJ Cole, AO Stella, CL Moreno, CE Denes, Z Hamoudi, ... bioRxiv, 2021.11. 09.467981, 2021 | 10 | 2021 |
| Scalable workflow for characterization of cell-cell communication in COVID-19 patients Y Lin, L Loo, A Tran, DM Lin, C Moreno, D Hesselson, GG Neely, ... PLOS Computational Biology 18 (10), e1010495, 2022 | 8 | 2022 |
Mark J. ZylkaThe University of North Carolina at Chapel HillVerified email at med.unc.edu