| G-protein-independent coupling of MC4R to Kir7. 1 in hypothalamic neurons M Ghamari-Langroudi, GJ Digby, JA Sebag, GL Millhauser, R Palomino, ... Nature 520 (7545), 94-98, 2015 | 213 | 2015 |
| Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers JA Sebag, PM Hinkle Proceedings of the National Academy of Sciences 104 (51), 20244-20249, 2007 | 184 | 2007 |
| Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish JA Sebag, C Zhang, PM Hinkle, AM Bradshaw, RD Cone Science 341 (6143), 278-281, 2013 | 163 | 2013 |
| Regions of melanocortin 2 (MC2) receptor accessory protein necessary for dual topology and MC2 receptor trafficking and signaling JA Sebag, PM Hinkle Journal of Biological Chemistry 284 (1), 610-618, 2009 | 145 | 2009 |
| Structure and function of the melanocortin2 receptor accessory protein (MRAP) PM Hinkle, JA Sebag Molecular and cellular endocrinology 300 (1-2), 25-31, 2009 | 112 | 2009 |
| Opposite effects of the melanocortin-2 (MC2) receptor accessory protein MRAP on MC2 and MC5 receptor dimerization and trafficking JA Sebag, PM Hinkle Journal of Biological Chemistry 284 (34), 22641-22648, 2009 | 102 | 2009 |
| Regulation of G protein–coupled receptor signaling: specific dominant-negative effects of melanocortin 2 receptor accessory protein 2 JA Sebag, PM Hinkle Science signaling 3 (116), ra28-ra28, 2010 | 87 | 2010 |
| The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1 AL Chaly, D Srisai, EE Gardner, JA Sebag Elife 5, e12397, 2016 | 86 | 2016 |
| MRAP2 regulates ghrelin receptor signaling and hunger sensing D Srisai, TC Yin, AA Lee, AAJ Rouault, NA Pearson, JL Grobe, JA Sebag Nature Communications 8 (1), 713, 2017 | 73 | 2017 |
| Physiological roles of the melanocortin MC3 receptor BJ Renquist, RN Lippert, JA Sebag, KLJ Ellacott, RD Cone European journal of pharmacology 660 (1), 13-20, 2011 | 71 | 2011 |
| Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling AAJ Rouault, AA Lee, JA Sebag Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (12), 2322-2329, 2017 | 61 | 2017 |
| Melanocortin receptor accessory proteins (MRAPs): functions in the melanocortin system and beyond AAJ Rouault, DK Srinivasan, TC Yin, AA Lee, JA Sebag Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (10 …, 2017 | 56 | 2017 |
| The GPCR accessory protein MRAP2 regulates both biased signaling and constitutive activity of the ghrelin receptor GHSR1a AAJ Rouault, LK Rosselli-Murai, CC Hernandez, LE Gimenez, GG Tall, ... Science signaling 13 (613), eaax4569, 2020 | 51 | 2020 |
| Functional expression of frog and rainbow trout melanocortin 2 receptors using heterologous MRAP1s L Liang, JA Sebag, L Eagelston, MN Serasinghe, K Veo, C Reinick, ... General and comparative endocrinology 174 (1), 5-14, 2011 | 51 | 2011 |
| Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay J Pantel, SY Williams, D Mi, J Sebag, JD Corbin, CD Weaver, RD Cone European journal of pharmacology 660 (1), 139-147, 2011 | 46 | 2011 |
| Neutrophils alter DNA repair landscape to impact survival and shape distinct therapeutic phenotypes of colorectal cancer TM Bui, V Butin-Israeli, HL Wiesolek, M Zhou, JF Rehring, L Wiesmüller, ... Gastroenterology 161 (1), 225-238. e15, 2021 | 37 | 2021 |
| Reduced mRNA expression of RGS2 (regulator of G protein signaling-2) in the placenta is associated with human preeclampsia and sufficient to cause features of the disorder in mice KJ Perschbacher, G Deng, JA Sandgren, JW Walsh, PC Witcher, ... Hypertension 75 (2), 569-579, 2020 | 34 | 2020 |
| A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells M Li, F Shao, Q Qian, W Yu, Z Zhang, B Chen, D Su, Y Guo, AV Phan, ... Molecular Therapy-Nucleic Acids 26, 307-320, 2021 | 29 | 2021 |
| Use of chimeric melanocortin-2 and-4 receptors to identify regions responsible for ligand specificity and dependence on melanocortin 2 receptor accessory protein PM Hinkle, MN Serasinghe, A Jakabowski, JA Sebag, KR Wilson, ... European journal of pharmacology 660 (1), 94-102, 2011 | 26 | 2011 |
| The insulinostatic effect of ghrelin requires MRAP2 expression in δ cells TC Yin, CJ Bauchle, AAJ Rouault, SB Stephens, JA Sebag Iscience 23 (6), 2020 | 15 | 2020 |