| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2580 | 2019 |
| Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2244 | 2011 |
| Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1485 | 2018 |
| Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease M Blurton-Jones, M Kitazawa, H Martinez-Coria, NA Castello, FJ Müller, ... Proceedings of the National Academy of Sciences 106 (32), 13594-13599, 2009 | 1063 | 2009 |
| iPSC-derived human microglia-like cells to study neurological diseases EM Abud, RN Ramirez, ES Martinez, LM Healy, CHH Nguyen, ... Neuron 94 (2), 278-293. e9, 2017 | 1014 | 2017 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 983 | 2017 |
| Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology RA Rissman, WW Poon, M Blurton-Jones, S Oddo, R Torp, MP Vitek, ... The Journal of clinical investigation 114 (1), 121-130, 2004 | 693 | 2004 |
| Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes G Jun, AC Naj, GW Beecham, LS Wang, J Buros, PJ Gallins, JD Buxbaum, ... Archives of neurology 67 (12), 1473-1484, 2010 | 519 | 2010 |
| Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis DC Whitcomb, J LaRusch, AM Krasinskas, L Klei, JP Smith, RE Brand, ... Nature genetics 44 (12), 1349-1354, 2012 | 417 | 2012 |
| The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function SE Marsh, EM Abud, A Lakatos, A Karimzadeh, ST Yeung, H Davtyan, ... Proceedings of the National Academy of Sciences 113 (9), E1316-E1325, 2016 | 416 | 2016 |
| Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid KE Nichol, WW Poon, AI Parachikova, DH Cribbs, CG Glabe, CW Cotman Journal of neuroinflammation 5, 1-15, 2008 | 321 | 2008 |
| A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 304 | 2016 |
| Assessment of the genetic variance of late-onset Alzheimer's disease PG Ridge, KB Hoyt, K Boehme, S Mukherjee, PK Crane, JL Haines, ... Neurobiology of aging 41, 200. e13-200. e20, 2016 | 276 | 2016 |
| β-Amyloid impairs axonal BDNF retrograde trafficking WW Poon, M Blurton-Jones, CH Tu, LM Feinberg, MA Chabrier, JW Harris, ... Neurobiology of aging 32 (5), 821-833, 2011 | 256 | 2011 |
| The role of caspase cleavage of tau in Alzheimer disease neuropathology CW Cotman, WW Poon, RA Rissman, M Blurton-Jones Journal of neuropathology & experimental neurology 64 (2), 104-112, 2005 | 250 | 2005 |
| Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss RR Ager, JL Davis, A Agazaryan, F Benavente, WW Poon, FM LaFerla, ... Hippocampus 25 (7), 813-826, 2015 | 247 | 2015 |
| Cholesterol and matrisome pathways dysregulated in astrocytes and microglia TCW Julia, L Qian, NH Pipalia, MJ Chao, SA Liang, Y Shi, BR Jain, ... Cell 185 (13), 2213-2233. e25, 2022 | 229 | 2022 |
| Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease L Zhang, S Trushin, TA Christensen, BV Bachmeier, B Gateno, ... Scientific reports 6 (1), 18725, 2016 | 226 | 2016 |
| Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study AC Naj, G Jun, C Reitz, BW Kunkle, W Perry, YS Park, GW Beecham, ... JAMA neurology 71 (11), 1394-1404, 2014 | 219 | 2014 |
| Transethnic genome‐wide scan identifies novel Alzheimer's disease loci GR Jun, J Chung, J Mez, R Barber, GW Beecham, DA Bennett, ... Alzheimer's & Dementia 13 (7), 727-738, 2017 | 196 | 2017 |
Mathew Blurton-JonesAssociate Professor Neurobiology and Behavior, University of California, IrvineVerified email at uci.edu