Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes. SE Kahn, S Andrikopoulos, CB Verchere Diabetes 48 (2), 241-253, 1999 | 653 | 1999 |
Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes TPM Scheithauer, E Rampanelli, M Nieuwdorp, BA Vallance, ... Frontiers in immunology 11, 571731, 2020 | 515 | 2020 |
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ... Nature medicine 13 (3), 340-347, 2007 | 489 | 2007 |
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. CB Verchere, DA D'Alessio, RD Palmiter, GC Weir, S Bonner-Weir, ... Proceedings of the National Academy of Sciences 93 (8), 3492-3496, 1996 | 353 | 1996 |
The flavanol (−)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP … F Meng, A Abedini, A Plesner, CB Verchere, DP Raleigh Biochemistry 49 (37), 8127-8133, 2010 | 320 | 2010 |
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood JD Trudeau, C Kelly-Smith, CB Verchere, JF Elliott, JP Dutz, DT Finegood, ... The Journal of clinical investigation 111 (2), 217-223, 2003 | 301 | 2003 |
Resident macrophages mediate islet amyloid polypeptide–induced islet IL-1β production and β-cell dysfunction CY Westwell-Roper, JA Ehses, CB Verchere Diabetes 63 (5), 1698-1711, 2014 | 263 | 2014 |
Islet amyloid polypeptide and type 2 diabetes L Marzban, K Park, CB Verchere Experimental gerontology 38 (4), 347-351, 2003 | 254 | 2003 |
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence? S Zraika, RL Hull, CB Verchere, A Clark, KJ Potter, PE Fraser, DP Raleigh, ... Diabetologia 53, 1046-1056, 2010 | 239 | 2010 |
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction C Westwell-Roper, DL Dai, G Soukhatcheva, KJ Potter, N van Rooijen, ... The journal of immunology 187 (5), 2755-2765, 2011 | 223 | 2011 |
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ... Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010 | 209 | 2010 |
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets JD Johnson, Z Ao, P Ao, H Li, LJ Dai, Z He, M Tee, KJ Potter, AM Klimek, ... Cell transplantation 18 (8), 833-845, 2009 | 198 | 2009 |
A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes GL Warnock, DM Thompson, RM Meloche, RJ Shapiro, Z Ao, P Keown, ... Transplantation 86 (12), 1762-1766, 2008 | 198 | 2008 |
Cholesterol in islet dysfunction and type 2 diabetes LR Brunham, JK Kruit, CB Verchere, MR Hayden The Journal of clinical investigation 118 (2), 403-408, 2008 | 194 | 2008 |
HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus JK Kruit, LR Brunham, CB Verchere, MR Hayden Current opinion in lipidology 21 (3), 178-185, 2010 | 191 | 2010 |
IL-33 reverses an obesity-induced deficit in visceral adipose tissue ST2+ T regulatory cells and ameliorates adipose tissue inflammation and insulin resistance JM Han, D Wu, HC Denroche, Y Yao, CB Verchere, MK Levings The Journal of Immunology 194 (10), 4777-4783, 2015 | 190 | 2015 |
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics A Abedini, A Plesner, P Cao, Z Ridgway, J Zhang, LH Tu, CT Middleton, ... Elife 5, e12977, 2016 | 176 | 2016 |
miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets N Wijesekara, L Zhang, MH Kang, T Abraham, A Bhattacharjee, ... Diabetes 61 (3), 653-658, 2012 | 172 | 2012 |
Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice S Ghosh, M Khazaei, F Moien-Afshari, LS Ang, DJ Granville, CB Verchere, ... American Journal of Physiology-Renal Physiology 296 (4), F700-F708, 2009 | 163 | 2009 |
Role of β-cell prohormone convertase (PC) 1/3 in processing of pro-islet amyloid polypeptide L Marzban, G Trigo-Gonzalez, X Zhu, CJ Rhodes, PA Halban, DF Steiner, ... Diabetes 53 (1), 141-148, 2004 | 157 | 2004 |