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Bruce Verchere
Bruce Verchere
Professor of Medicine University of British Columbia and BC Children's Hospital Research Institute
Verified email at mail.ubc.ca - Homepage
Title
Cited by
Cited by
Year
Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.
SE Kahn, S Andrikopoulos, CB Verchere
Diabetes 48 (2), 241-253, 1999
6531999
Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes
TPM Scheithauer, E Rampanelli, M Nieuwdorp, BA Vallance, ...
Frontiers in immunology 11, 571731, 2020
5152020
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ...
Nature medicine 13 (3), 340-347, 2007
4892007
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.
CB Verchere, DA D'Alessio, RD Palmiter, GC Weir, S Bonner-Weir, ...
Proceedings of the National Academy of Sciences 93 (8), 3492-3496, 1996
3531996
The flavanol (−)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP …
F Meng, A Abedini, A Plesner, CB Verchere, DP Raleigh
Biochemistry 49 (37), 8127-8133, 2010
3202010
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
JD Trudeau, C Kelly-Smith, CB Verchere, JF Elliott, JP Dutz, DT Finegood, ...
The Journal of clinical investigation 111 (2), 217-223, 2003
3012003
Resident macrophages mediate islet amyloid polypeptide–induced islet IL-1β production and β-cell dysfunction
CY Westwell-Roper, JA Ehses, CB Verchere
Diabetes 63 (5), 1698-1711, 2014
2632014
Islet amyloid polypeptide and type 2 diabetes
L Marzban, K Park, CB Verchere
Experimental gerontology 38 (4), 347-351, 2003
2542003
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?
S Zraika, RL Hull, CB Verchere, A Clark, KJ Potter, PE Fraser, DP Raleigh, ...
Diabetologia 53, 1046-1056, 2010
2392010
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction
C Westwell-Roper, DL Dai, G Soukhatcheva, KJ Potter, N van Rooijen, ...
The journal of immunology 187 (5), 2755-2765, 2011
2232011
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts
KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ...
Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010
2092010
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets
JD Johnson, Z Ao, P Ao, H Li, LJ Dai, Z He, M Tee, KJ Potter, AM Klimek, ...
Cell transplantation 18 (8), 833-845, 2009
1982009
A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes
GL Warnock, DM Thompson, RM Meloche, RJ Shapiro, Z Ao, P Keown, ...
Transplantation 86 (12), 1762-1766, 2008
1982008
Cholesterol in islet dysfunction and type 2 diabetes
LR Brunham, JK Kruit, CB Verchere, MR Hayden
The Journal of clinical investigation 118 (2), 403-408, 2008
1942008
HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus
JK Kruit, LR Brunham, CB Verchere, MR Hayden
Current opinion in lipidology 21 (3), 178-185, 2010
1912010
IL-33 reverses an obesity-induced deficit in visceral adipose tissue ST2+ T regulatory cells and ameliorates adipose tissue inflammation and insulin resistance
JM Han, D Wu, HC Denroche, Y Yao, CB Verchere, MK Levings
The Journal of Immunology 194 (10), 4777-4783, 2015
1902015
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
A Abedini, A Plesner, P Cao, Z Ridgway, J Zhang, LH Tu, CT Middleton, ...
Elife 5, e12977, 2016
1762016
miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets
N Wijesekara, L Zhang, MH Kang, T Abraham, A Bhattacharjee, ...
Diabetes 61 (3), 653-658, 2012
1722012
Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice
S Ghosh, M Khazaei, F Moien-Afshari, LS Ang, DJ Granville, CB Verchere, ...
American Journal of Physiology-Renal Physiology 296 (4), F700-F708, 2009
1632009
Role of β-cell prohormone convertase (PC) 1/3 in processing of pro-islet amyloid polypeptide
L Marzban, G Trigo-Gonzalez, X Zhu, CJ Rhodes, PA Halban, DF Steiner, ...
Diabetes 53 (1), 141-148, 2004
1572004
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