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Alaa A.-M. Abdel-Aziz PhD
Alaa A.-M. Abdel-Aziz PhD
King Saud University, Mansoura University, Kumamoto University
Verified email at ksu.edu.sa
Title
Cited by
Cited by
Year
Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study
AS El-Azab, MA Al-Omar, AM Alaa, NI Abdel-Aziz, AA Magda, AM Aleisa, ...
European journal of medicinal chemistry 45 (9), 4188-4198, 2010
2992010
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4 (3H)-quinazolinone analogs
ST Al-Rashood, IA Aboldahab, MN Nagi, LA Abouzeid, AAM Abdel-Aziz, ...
Bioorganic & medicinal chemistry 14 (24), 8608-8621, 2006
2522006
Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4 (3H)-quinazolinone analogs
AM Al-Obaid, SG Abdel-Hamide, HA El-Kashef, AM Alaa, AS El-Azab, ...
European journal of medicinal chemistry 44 (6), 2379-2391, 2009
2362009
Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study
AM Alaa
European journal of medicinal chemistry 42 (5), 614-626, 2007
1992007
Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, YA Asiri, KEH ElTahir
Bioorganic & medicinal chemistry 19 (11), 3416-3424, 2011
1932011
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, KEH ElTahir
Bioorganic & medicinal chemistry 20 (10), 3306-3316, 2012
1792012
Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2, 6-substituted-quinazolin-4-ones
FAM Al-Omary, LA Abou-Zeid, MN Nagi, ESE Habib, AM Alaa, AS El-Azab, ...
Bioorganic & medicinal chemistry 18 (8), 2849-2863, 2010
1662010
Synthesis, antimicrobial activity and conformational analysis of novel substituted pyridines: BF3-promoted reaction of hydrazine with 2-alkoxy pyridines
FE Goda, AM Alaa, OA Attef
Bioorganic & medicinal chemistry 12 (8), 1845-1852, 2004
1572004
Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities
AM Alanazi, AS El-Azab, IA Al-Suwaidan, KEH ElTahir, YA Asiri, ...
European journal of medicinal chemistry 92, 115-123, 2015
1392015
Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study
AM Alaa, KEH ElTahir, YA Asiri
European journal of medicinal chemistry 46 (5), 1648-1655, 2011
1262011
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4 (3H)-quinazolinones
AM Alaa, LA Abou-Zeid, KEH ElTahir, RR Ayyad, AA Magda, AS El-Azab
European Journal of Medicinal Chemistry 121, 410-421, 2016
1162016
Synthesis and biological evaluation of some novel cyclic-imides as hypoglycaemic, anti-hyperlipidemic agents
AM Alaa, AS El-Azab, SM Attia, AM Al-Obaid, MA Al-Omar, HI El-Subbagh
European journal of medicinal chemistry 46 (9), 4324-4329, 2011
108*2011
Synthesis and antitumor evaluation of trimethoxyanilides based on 4 (3H)-quinazolinone scaffolds
MA Mohamed, RR Ayyad, TZ Shawer, AM Alaa, AS El-Azab
European journal of medicinal chemistry 112, 106-113, 2016
1062016
Synthesis, antimicrobial activity and molecular modeling of cobalt and nickel complexes containing the bulky ligand: bis [N-(2, 6-diisopropylphenyl) imino] acenaphthene
U El-Ayaan, AM Alaa
European Journal of Medicinal Chemistry 40 (12), 1214-1221, 2005
982005
Design, synthesis of 2, 3-disubstitued 4 (3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies
AM Alaa, LA Abou-Zeid, KEH ElTahir, MA Mohamed, MAA El-Enin, ...
Bioorganic & Medicinal Chemistry 24 (16), 3818-3828, 2016
912016
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibition activities and molecular docking study of pyrazoline derivatives
MA Abdel-Sayed, SM Bayomi, MA El-Sherbeny, NI Abdel-Aziz, ...
Bioorganic & Medicinal Chemistry 24 (9), 2032-2042, 2016
912016
Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4 (3H) quinazolinone analogues
IA Al-Suwaidan, AAM Abdel-Aziz, TZ Shawer, RR Ayyad, AM Alanazi, ...
Journal of enzyme inhibition and medicinal chemistry 31 (1), 78-89, 2016
912016
Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: dual cyclooxygenase/carbonic anhydrase inhibitory actions
AM Alaa, A Angeli, AS El-Azab, MEA Hammouda, MA El-Sherbeny, ...
Bioorganic chemistry 84, 260-268, 2019
902019
Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment
AH El-Kamel, AM Alaa, AJ Fatani, HI El-Subbagh
International journal of pharmaceutics 358 (1-2), 248-255, 2008
892008
Lewis acid-promoted transformation of 2-alkoxypyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation
AM Alaa, HI El-Subbagh, T Kunieda
Bioorganic & medicinal chemistry 13 (16), 4929-4935, 2005
852005
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