Premature ageing in mice expressing defective mitochondrial DNA polymerase A Trifunovic, A Wredenberg, M Falkenberg, JN Spelbrink, AT Rovio, ... Nature 429 (6990), 417-423, 2004 | 3171 | 2004 |
Mitochondrial transcription factor A regulates mtDNA copy number in mammals MI Ekstrand, M Falkenberg, A Rantanen, CB Park, M Gaspari, K Hultenby, ... Human molecular genetics 13 (9), 935-944, 2004 | 1056 | 2004 |
DNA replication and transcription in mammalian mitochondria M Falkenberg, NG Larsson, CM Gustafsson Annu. Rev. Biochem. 76 (1), 679-699, 2007 | 873 | 2007 |
Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA M Falkenberg, M Gaspari, A Rantanen, A Trifunovic, NG Larsson, ... Nature genetics 31 (3), 289-294, 2002 | 769 | 2002 |
Maintenance and expression of mammalian mitochondrial DNA CM Gustafsson, M Falkenberg, NG Larsson Annual review of biochemistry 85 (1), 133-160, 2016 | 729 | 2016 |
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA C Kukat, CA Wurm, H Spåhr, M Falkenberg, NG Larsson, S Jakobs Proceedings of the National Academy of Sciences 108 (33), 13534-13539, 2011 | 674 | 2011 |
Reconstitution of a minimal mtDNA replisome in vitro JA Korhonen, XH Pham, M Pellegrini, M Falkenberg The EMBO journal 23 (12), 2423-2429, 2004 | 490 | 2004 |
Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid C Kukat, KM Davies, CA Wurm, H Spåhr, NA Bonekamp, I Kühl, F Joos, ... Proceedings of the National Academy of Sciences 112 (36), 11288-11293, 2015 | 375 | 2015 |
TWINKLE has 5′→ 3′ DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein JA Korhonen, M Gaspari, M Falkenberg Journal of Biological Chemistry 278 (49), 48627-48632, 2003 | 368 | 2003 |
Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging J van Mameren, P Gross, G Farge, P Hooijman, M Modesti, M Falkenberg, ... Proceedings of the National Academy of Sciences 106 (43), 18231-18236, 2009 | 337 | 2009 |
MTERF3 is a negative regulator of mammalian mtDNA transcription CB Park, J Asin-Cayuela, Y Cámara, Y Shi, M Pellegrini, M Gaspari, ... Cell 130 (2), 273-285, 2007 | 291 | 2007 |
Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro D Litonin, M Sologub, Y Shi, M Savkina, M Anikin, M Falkenberg, ... Journal of Biological Chemistry 285 (24), 18129-18133, 2010 | 275 | 2010 |
Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication JM Fusté, S Wanrooij, E Jemt, CE Granycome, TJ Cluett, Y Shi, ... Molecular cell 37 (1), 67-78, 2010 | 272 | 2010 |
Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro S Wanrooij, JM Fusté, G Farge, Y Shi, CM Gustafsson, M Falkenberg Proceedings of the National Academy of Sciences 105 (32), 11122-11127, 2008 | 234 | 2008 |
Mammalian transcription factor A is a core component of the mitochondrial transcription machinery Y Shi, A Dierckx, PH Wanrooij, S Wanrooij, NG Larsson, LM Wilhelmsson, ... Proceedings of the National Academy of Sciences 109 (41), 16510-16515, 2012 | 225 | 2012 |
The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells M Gaspari, M Falkenberg, NG Larsson, CM Gustafsson The EMBO journal 23 (23), 4606-4614, 2004 | 218 | 2004 |
Mitochondrial DNA replication in mammalian cells: overview of the pathway M Falkenberg Essays in biochemistry 62 (3), 287-296, 2018 | 215 | 2018 |
G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation PH Wanrooij, JP Uhler, T Simonsson, M Falkenberg, CM Gustafsson Proceedings of the National Academy of Sciences 107 (37), 16072-16077, 2010 | 212 | 2010 |
A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop PH Wanrooij, JP Uhler, Y Shi, F Westerlund, M Falkenberg, ... Nucleic acids research 40 (20), 10334-10344, 2012 | 190 | 2012 |
TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication D Milenkovic, S Matic, I Kühl, B Ruzzenente, C Freyer, E Jemt, CB Park, ... Human molecular genetics 22 (10), 1983-1993, 2013 | 182 | 2013 |