The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription S Cogoi, A Ferino, G Miglietta, EB Pedersen, LE Xodo Nucleic acids research 46 (2), 661-676, 2018 | 133 | 2018 |
G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders G Miglietta, M Russo, G Capranico Nucleic acids research 48 (21), 11942-11957, 2020 | 113 | 2020 |
RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation G Miglietta, S Cogoi, J Marinello, G Capranico, AS Tikhomirov, ... Journal of Medicinal Chemistry 60 (23), 9448-9461, 2017 | 77 | 2017 |
GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1 G Miglietta, S Cogoi, EB Pedersen, LE Xodo Scientific Reports 5 (1), 18097, 2015 | 63 | 2015 |
Monohydrazone based G-quadruplex selective ligands induce DNA damage and genome instability in human cancer cells J Amato, G Miglietta, R Morigi, N Iaccarino, A Locatelli, A Leoni, ... Journal of medicinal chemistry 63 (6), 3090-3103, 2020 | 46 | 2020 |
G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells G Miglietta, M Russo, RC Duardo, G Capranico Nucleic acids research 49 (12), 6673-6686, 2021 | 43 | 2021 |
MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells A Ferino, G Miglietta, R Picco, S Vogel, J Wengel, LE Xodo RNA biology 15 (10), 1273-1285, 2018 | 36 | 2018 |
Ligands stimulating antitumour immunity as the next G-quadruplex challenge G Miglietta, J Marinello, M Russo, G Capranico Molecular Cancer 21 (1), 180, 2022 | 27 | 2022 |
Nucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism G Miglietta, AS Gouda, S Cogoi, EB Pedersen, LE Xodo ACS Medicinal Chemistry Letters 6 (12), 1179-1183, 2015 | 22 | 2015 |
Balancing affinity, selectivity, and cytotoxicity of hydrazone-based G-quadruplex ligands for activation of interferon β genes in cancer cells S Marzano, G Miglietta, R Morigi, J Marinello, A Arleo, M Procacci, ... Journal of medicinal chemistry 65 (18), 12055-12067, 2022 | 10 | 2022 |
Immunofluorescence microscopy of G-quadruplexes and R-loops G Miglietta, J Marinello, G Capranico Methods in Enzymology 695, 103-118, 2024 | 3 | 2024 |
Stimulation of cGAS-STING pathway as a challenge in the treatment of small cell lung cancer: a feasible strategy? G Miglietta, M Russo, G Capranico, J Marinello British Journal of Cancer 131 (10), 1567-1575, 2024 | 2 | 2024 |
“Le varianti della rosa”. Per un prototipo di edizione digitale del Nome della rosa: interpretazione didattica annotazione C D’Agata, F Cirací, G Miglietta, C Gatto AIUCD 2022-Culture digitali. Intersezioni: filosofia, arti, media …, 2022 | 1 | 2022 |
G4 binders as potential immunostimulatory compounds for cancer therapy M Russo, G Miglietta, G Capranico Cancer Research 81 (13_Supplement), 1234-1234, 2021 | 1 | 2021 |
G-quadruplex RNA in Kirsten ras transcript as promising target for anticancer therapy A Tikhomirov, G Miglietta, S Cogoi, A Shchekotikhin, L Xodo FEBS OPEN BIO 8, 114-114, 2018 | | 2018 |
Unusual nucleic acid structures in the RAS genes and design of anti-cancer strategies G Miglietta Università degli Studi di Udine, 2018 | | 2018 |
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents R Morigi, J Amato, N Iaccarino, B Pagano, A Locatelli, A Leoni, ... BIONIC 2018: Biology of non-canonical nucleic acids: from humans to …, 2018 | | 2018 |