| The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells DA Ryskamp, P Witkovsky, P Barabas, W Huang, C Koehler, NP Akimov, ... Journal of Neuroscience 31 (19), 7089-7101, 2011 | 250 | 2011 |
| TRPV4 and AQP4 channels synergistically regulate cell volume and calcium homeostasis in retinal Müller glia AO Jo, DA Ryskamp, TTT Phuong, AS Verkman, O Yarishkin, N MacAulay, ... Journal of Neuroscience 35 (39), 13525-13537, 2015 | 235 | 2015 |
| Neuronal sigma-1 receptors: signaling functions and protective roles in neurodegenerative diseases DA Ryskamp, S Korban, V Zhemkov, N Kraskovskaya, I Bezprozvanny Frontiers in Neuroscience 13, 474181, 2019 | 183 | 2019 |
| From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma D Križaj, DA Ryskamp, N Tian, G Tezel, CH Mitchell, VZ Slepak, ... Current eye research 39 (2), 105-119, 2014 | 172 | 2014 |
| Enhanced store-operated calcium entry leads to striatal synaptic loss in a Huntington's disease mouse model J Wu, DA Ryskamp, X Liang, P Egorova, O Zakharova, G Hung, ... Journal of neuroscience 36 (1), 125-141, 2016 | 160 | 2016 |
| The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease D Ryskamp, J Wu, M Geva, R Kusko, I Grossman, M Hayden, ... Neurobiology of disease 97, 46-59, 2017 | 134 | 2017 |
| TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye DA Ryskamp, AM Frye, TTT Phuong, O Yarishkin, AO Jo, Y Xu, M Lakk, ... Scientific reports 6 (1), 30583, 2016 | 133 | 2016 |
| Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia DA Ryskamp, AO Jo, AM Frye, F Vazquez-Chona, N MacAulay, ... Journal of Neuroscience 34 (47), 15689-15700, 2014 | 113 | 2014 |
| Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice T Zu, S Guo, O Bardhi, DA Ryskamp, J Li, S Khoramian Tusi, ... Proceedings of the National Academy of Sciences 117 (31), 18591-18599, 2020 | 105 | 2020 |
| AF710B, a novel M1/σ1 agonist with therapeutic efficacy in animal models of Alzheimer's disease A Fisher, I Bezprozvanny, L Wu, DA Ryskamp, N Bar-Ner, N Natan, ... Neurodegenerative Diseases 16 (1-2), 95-110, 2016 | 79 | 2016 |
| Pridopidine stabilizes mushroom spines in mouse models of Alzheimer's disease by acting on the sigma-1 receptor D Ryskamp, L Wu, J Wu, D Kim, G Rammes, M Geva, M Hayden, ... Neurobiology of disease 124, 489-504, 2019 | 67 | 2019 |
| TRPV1 and endocannabinoids: emerging molecular signals that modulate mammalian vision DA Ryskamp, S Redmon, AO Jo, D Križaj Cells 3 (3), 914-938, 2014 | 67 | 2014 |
| Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice GS Zu T, O Bardhi, DA Ryskamp, J Li, SK Tusi, A Engelbrecht, K Klippel, ... Proc Natl Acad Sci USA 117 (31), 18591-18599, 2020 | 55 | 2020 |
| Inhibition of TRPC1-dependent store-operated calcium entry improves synaptic stability and motor performance in a mouse model of Huntington’s disease J Wu, D Ryskamp, L Birnbaumer, I Bezprozvanny Journal of Huntington's disease 7 (1), 35-50, 2018 | 55 | 2018 |
| Mouse retinal ganglion cell signalling is dynamically modulated through parallel anterograde activation of cannabinoid and vanilloid pathways AO Jo, JM Noel, M Lakk, O Yarishkin, DA Ryskamp, K Shibasaki, ... The Journal of physiology 595 (20), 6499-6516, 2017 | 35 | 2017 |
| TRPV4 links inflammatory signaling and neuroglial swelling DA Ryskamp, A Iuso, D Križaj Channels 9 (2), 70-72, 2015 | 27 | 2015 |
| Localization and phenotype-specific expression of ryanodine calcium release channels in C57BL6 and DBA/2J mouse strains W Huang, W Xing, DA Ryskamp, C Punzo, D Križaj Experimental eye research 93 (5), 700-709, 2011 | 27 | 2011 |
| Drofenine: a 2‐APB analog with improved selectivity for human TRPV3 CE Deering‐Rice, VK Mitchell, EG Romero, MH Abdel Aziz, DA Ryskamp, ... Pharmacology research & perspectives 2 (5), e00062, 2014 | 25 | 2014 |
| UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice DR Rijsketic, AB Casey, DAN Barbosa, X Zhang, TM Hietamies, ... Neuropsychopharmacology 48 (12), 1798-1807, 2023 | 21 | 2023 |
| Mutational analysis of sigma-1 receptor’s role in synaptic stability DA Ryskamp, V Zhemkov, I Bezprozvanny Frontiers in Neuroscience 13, 1012, 2019 | 18 | 2019 |
David KrizajProfessor of Ophthalmology & Visual Science, University of UtahVerified email at hsc.utah.edu
